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In summary, our results indicate that hypohidrosis is a frequent adverse effect in children with topiramate therapy. Younger age and hot weather rather than drug dosage are independent risk factors for topiramate-associated hypohidrosis. The resultes also rule out the possibility that topiramate act on its known mechanisms of action, such as potentiating GABA activity at GABAA receptors and antagonizing the AMPA/KA subtype of glutamate receptor in the secretory cells of sweat glands to inhibit sweat secretion. Our data also suggest that topiramate impairs sudomotor function in mice and leads to a significant reduction in AQP5 expression in sweat glands of anhidrotic mice, thus raising the possibility that dysregulation of AQP5 may contribute to topiramate related hypohidrosis.

综合全部实验结果，本研究提示：夏季和低龄是托吡酯引起泌汗障碍的主要危险因素，而托吡酯剂量对泌汗(来源：A44B8787C论文网www.abclunwen.com)功能的影响较小；托吡酯可以抑制小鼠汗液的分泌，小鼠的年龄并不影响这种抑制作用，但托吡酯对小鼠体温无明显影响；托吡酯并不是通过对GABAA受体及AMPA和KA两种谷氨酸受体亚型的作用而在汗腺分泌细胞抑制泌汗；托吡酯不影响汗腺形态及Na，K-ATP酶活性；汗腺分泌细胞的AQP5功能失调可能与托吡酯引起的泌汗障碍密切相关，而碳酸酐酶抑制作用并不是泌汗功能损害的主要原因。

Darwinism:达尔文主义:an evident influence on naturalism, stress the animality of man, to suggest that be was dominated by the irresistible forces of evolution.

对自然主义影响极大，强调人的动物性，意味着人的命运受进化的不可抗力来决定的。

"I suggest that before you do anything, you ask a most important question," Qui-Gon said."Rumors don't arise out of the air. If the Annihilator is a fabrication, who made it up?"

"我提议，在你们有所动作之前，应该先考虑一个重要的问题，"魁刚说，"谣言并非空穴来风，如果说Annihilator是个骗局，是谁精心编制了它？"

To give a hopelessly commonsense answer to a question is a very common device to suggest the answerer's reluctance to reply and to propose a change in topic in a polite, implicit, and somewhat humorous way.

四、按照一般的逻辑，一个美人嫁给一个离异、年老的男人，通常不是为了爱，而是为了钱，因此Mary影射这位继母是一个"傍大款"的贪婪女人。

To gie a hopelessly commonsense answer to a question is a ery common deice to suggest the answerer's reluctance to reply and to propose a change in topic in a polite, implicit, and somewhat humorous way.

总之，语用学确实是一门很有趣的学科，遗憾的是，在我们中国的英语教学中，并不教授这门课程，因而造成许多学生不能准确理解外国人讲话的真正含义。

You made an inconspicuous movement of the head,to suggest my coming into the anteroom for a moment.

你微微摆动了一下脑袋，向我示意，要我到前厅去一会儿。

The results suggest: the three culturalss pollen germination percentage were more than 60% 4 h after cultured in liquid culture medium composed 10% sucrose, 24℃; Florescence most concentrated April third-tenth (2003); For Zaomeisu and Qiyuesu ,their anthotaxy and flower self setting fruit percentage were more than 90%,except for China pear 1, anthotaxy self setting fruit percentage was 48.3%, flower self setting fruit percentage was 33.1%; Their cross-compatibility was higher, anthotaxy and flower self setting fruit percentage almost reached 100%, the lowest also reached 94.9%, but last self-compatible gathering fruit percentage was lower comparatively and fruit average seed numbers were lower, while cross-compatible gathering fruit percentage and fruit average seed numbers were closed to that of nature pollination.

对梨品种亲缘关系很近的早美酥、中梨1号、七月酥等进行的花粉发芽率、花期调查、自交亲和性、异交亲和性调查的结果表明：三者的花粉在10%的蔗糖液培养基上，24℃左右培养4h后花粉发芽率均能达到60%以上；三者的花期大都集中在4月3日-10日(2003年)；早美酥、中梨1号、七月酥的自花授粉坐果率，除中梨1号的花序自花授粉座果率为48.3%，花朵自交座果率为33.1%外，早美酥、七月酥的花序自交座果率和花朵自自花授粉座果率均达到90%以上；它们的异花授粉坐果率更高，在本试验中花序坐果率和花朵坐果率都可达到94%以上，但最终采果率自花授粉的相对低一些，果实平均种子数也低，异花授粉的最终采果率和果实平均种子数与自然授粉条件下的近似。

During the period of the Popular Front, from 1935 to 1938, when the Communist Party sought alliances with progressive groups in the name of anti-Fascism, it was therefore unseemly to suggest any similarity between Communism and Fascism as forms of government.

在1935年至1938年的人民阵线时期，共产党在反法西斯的名义下寻求与进步群体联合，因此，任何试图在作为政府形式的共产主义和法西斯主义之间提出相似性都是不适宜的。

Books like this are not anti-intellectual as such; they merely suggest that, in the evolutionary race, it is an error to bet too heavily on the brain.

那些只是假设在进化竞赛中，在大脑上不应赌得过大的书，不属于反智力的范围。

My question is, is this really uncommon and if so, would you suggest taking the antibody test again.

我的问题是，如果这真的不正常，你建议我再测抗体麼。

On the other hand, the more important thing is because the urban housing is a kind of heterogeneity products.

另一方面，更重要的是由于城市住房是一种异质性产品。

Climate histogram is the fall that collects place measure calm value, cent serves as cross axle for a few equal interval, the area that the frequency that the value appears according to place is accumulated and becomes will be determined inside each interval, discharge the graph that rise with post, also be called histogram.

气候直方图是将所收集的降水量测定值，分为几个相等的区间作为横轴，并将各区间内所测定值依所出现的次数累积而成的面积，用柱子排起来的图形，也叫做柱状图。