查询词典 street virus

Objective To compare the G genes of novel rabies street virus strain isolated in Zhejiang Province, China and other vaccine virus strain used in China and abroad.

目的 对浙江新近分离的2株狂犬病病毒街毒株的G基因进行遗传学分析，并比较其与国内外使用的狂犬病疫苗株间的差异。

In order to rich rabies virus gene bank, sequencing and analyzing parts of the two rabies virus street strains isolated from different animals in China.

本研究为了丰富我国狂犬病基因库，对我国不同动物中分离到的两个野毒株进行基因组部分序列的测定和分析。

The guinea pigs were infected with the street rabies virus strain and adaptive Bei-jing fixed rabies virus strain.

狂犬病是人和家畜的一种急性中枢神经系统的疾病，严重地威胁人类和家畜的生命。

Objective To analyze the sequence of glycoprotein gene of three passages of rabies vaccine strain CTN-1-V in China and compare with that of street virus strain.

目的 分析三个代次CTN-1-V病毒株糖蛋白基因部分序列，并与代表性街毒株进行比较。

The two novel rabies street virus strains isolated in Zhejiang Province, China were of genotype I and located in the same branch with CTN strain on phylogenetic tree.

浙江新分离的2株狂犬病病毒街毒株属于基因1型，与当前使用的多种疫苗株相比，与CTN疫苗株属于同一分支，二者的亲缘关系最近。

Results Rabies virus was detected in both dog brain tissue samples ZJCA1 and LH, of which the homologies of nucleotide and amino acid sequences of Ggene were 98.7%-99.2% to those of other street virus strains isolated in Zhejiang Province, and 79.5%-86.1% and 86.8%-94.1% to those of CTN strain respectively.

与当前国内外使用的多种疫苗株相比，与CTN疫苗株同源性最高，G基因核苷酸和氨基酸序列同源性分别为79.5%~86.1%和

It is indicated that MRV and street viruses have close phylogenic relation by analyzing the phylogenic tree of eachgene of MRV, and it is short evolutionary time between MRV and DRV by analyzingthe phylogenic tree of L gene. It is illuminated that MRV and street virus in China andAfrica have close phylogenic relation by analyzing phylogenic trees of other genes.Therefore, we can speculate that MRV is a Chinese street rabies virus isolated, whichis a new virus isolated because of variance and evolution of the rabies virus after itinfected mouse.

MRV的各个基因进化树表明，其与野毒株具有较近的亲缘关系，通过L基因的进化树分析，两个毒株的进化时间较短，其他基因进化树分析表明，MRV与亚洲和中国流行的野毒株具有较近的亲缘关系，所以推测MRV应该是中国固有的野毒株，由于某种原因感染野鼠后病毒进化变异而产生的毒株。

In this study, the cDNA fragments of G-L intergenic region and polymerase activity module in L gene of two street rabies virus were cloned and sequenced. The nucleotides sequence of these cDNA fragments mentioned above and their deduced amino acid sequence were compared with that of rabies virus strains, rabies-related virus strains and other Rliabdoviridae published previously. The result show that the homology of nucleotide sequence of G-L IGR among MRV, DRV is 83.3%, compared with other rabies-related virus strains, the homology of G-L IGR is between 58.3%-91.7%. the length of G-L IGR of rabies virus is different in Rhabdoviridae.

本实验对狂犬病病毒野毒株MRV、DRV的G-L间隔区以及L基因聚合酶活性部位进行了克隆和测序，将所测定的结果和推定的氨基酸序列与国内外公开发表的狂犬病病毒其它固定毒株、野毒株和同科不同属的病毒的相应部分进行了分析比较，结果表明MRV、DRV G-L IGR核苷酸序列的同源性为83.3％，与其它毒株的同源性在58.3％～91.7％之间；狂犬病毒G-L间隔区序列的长度在弹状病毒科不同病毒属之间有所不同。

The homologies of nucleotides and amino acids of G genes of the three isolates were 82.8%-83.1% and 88.0%-90.1% to those of aG, PV and ERA strains, and 86.7%-87.1% and 92.0% to those of CTN strain respectively. Conclusion Few variation was observed in the five rabies street virus strains isolated recently in China.

将3株街毒与人用疫苗株aG、PV和兽用疫苗株ERA的G基因进行比较，核苷酸同源性在82.8%~83.1%之间，氨基酸同源性在88.0%~90.1%之间；而与人用疫苗株CTN比较，核苷酸同源性在86.7%~87.1%之间，氨基酸同源性均为92.0%。

Neutralizing potency of the patent recombinant anti-rabies virus McAbs, SO57 and SOJB,have been investigated broadly to different rabies virus strains in various animal models.100% Chinese Hamsters could be protected by 100IU/kg SO57 against China prevalent street rabies virus named SBD.We firstly established the mouse model to simulate human postexposure prophylaxis by rabies virus and found SO57 had the same function with HRIG against CVS or three China typical street rabies viruses.However,HRIG could not 100% protect the mice challenged with SBD street virus,rabies virus vaccine alone could not save life from rabies virus infection.The cocktail containing SOJB and SO57(1:1) did not do better than SO57 alone.

用不同的动物模型研究了具有专利的重组人抗狂犬病病毒单克隆抗体SO57、SOJB对不同狂犬病病毒株的中和作用，100IU/kg的SO57能100%保护被中国街毒株SBD攻击的中国仓鼠；首次用小鼠模型模拟人体被狂犬病病毒攻击后的治疗情况，在小鼠被CVS及中国街毒代表株攻击后，SO57与HRIG具有相近的对小鼠的暴露后保护作用；同时结果显示HRIG对SBD株攻击的保护率不能到达100%，仅使用疫苗是不能对感染病毒的小鼠百分之百的保护；SOJB与SO57 1：1联合使用未显示比SO57单独使用更好的保护效果。

Singer Leona Lewis and former Led Zeppelin guitarist Jimmy Page emerged as the bus transformed into a grass-covered carnival float, and the pair combined for a rendition of "Whole Lotta Love".

歌手leona刘易斯和前率领的飞艇的吉他手吉米页出现巴士转化为基层所涵盖的嘉年华花车，和一双合并为一移交&整个lotta爱&。

This is Kate, and that's Erin.

这是凯特，那个是爱朗。