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RESULTS: The neural stem cells isolated from neonatal rat brains had the potential of serial passage and proliferation, besides, they express neuroepithelial stem cell protein and differentiate into neurons, astrocytes and oligodendrocytes.

诱导分化后的细胞能表达神经元细胞、星形胶质细胞、少突胶质细胞的特异性蛋白。

Results: The Schwann cells promoted the survival and differentiation of neuroepithelial stem cells, and the number of the neurons decreased with an increase of serum concentration. Both the neuroepithelial stem cells and serum promoted the survival and the proliferation of the Schwann cells.

结果:Schwann细胞促进神经上皮干细胞存活和分化,随着血清浓度增加,神经上皮干细胞分化形成的神经元比例减少;神经上皮干细胞及血清均促进Schwann细胞存活和增殖,随血清浓度增加,存活及增殖率增加。

Human embryonic stem cells can differentiate into neuroepithelial progenitor cells in both feeder containing and feeder free systems,yet feeder free system has a relatively lower inductive efficiency with part of undifferentiated embryonic stem cells.

人胚胎干细胞在有饲养层和无饲养层体系中均可诱导分化形成神经上皮祖细胞,但无饲养层体系的效率相对较低,且有未分化胚胎干细胞残余。

BMSCs can be induced into neural stem cells and further neural stem cells derived from bone marrow can differentiate into neural cells and neuroglial cells.

骨髓基质细胞能在体外诱导分化出神经干细胞,且骨髓源性神经干细胞可进一步定向分化为神经细胞及神经胶质细胞。

Bone marrow stromal cells are cells got rid of hemopoietic stem cells in marrow cell of mature individual, which is approved to be multi-differentiation potential including transforming into neural stem cell, and differentiation into neurs and neuroglial cell.

骨髓基质细胞(Bone marrow stromal cells,BMSCs)是成体骨髓细胞中除造血干细胞之外的另一类骨髓干细胞,近年来的研究证明其具有多向分化的潜能,包括向神经干细胞转化,并可进一步分化为神经元和神经胶质细胞。

This review focuses on the current research progress of the liver cell differentiation source, and it also discusses the advantages and disadvantages of various hepatic stem cells and nonhepatic stem cells, expecting to provide a reference for liver cell source selection during tissue engineering, an adequate and suitable source for bioartificial liver and hepatocyte transplantation and to help to treat liver diseases.

本文着重论述了目前肝脏细胞的分化来源研究进展情况,并对各种肝源性和非肝源性干细胞的优缺点进行了讨论,以期为肝组织工程选择细胞来源提供参考,为生物人工肝、肝细胞移植提供充足、合适的细胞来源,协助治疗肝脏疾病。

The peony duplicate leaf has stretches out straight in front of oneself, slanting extends the different shape, after the general stem is long four handles stems, only then can have the bud appearance, each handle stem leaf has three groups of three leaf blades productions, constitutes three forks nine peonies to have stands erect, half development, develops three kind of shapes, the flower bud has the circle, oblately, the point round, long sharp circle Zhu Xing?

牡丹复叶有平伸、斜伸不同形态,一般枝梗长出四柄梗后,才会有蓓蕾出现,每柄梗叶有三组三顶叶片生成,构成三叉九顶。牡丹有直立、半开展、开展三种株形,花蕾有圆、扁圆、尖圆、长尖圆诸形。

Notch1 is expressed by stem cells resided in the cervical loop epithelium, and Notch signaling pathway play a central role in fate decision of those stem cells. Notch receptors and their ligands are involved in both patterning and cell fate determination during odontogenesis. Moreover, many cell factors, which are closely related with odontogenesis, could regulate expression of Notch receptors or their ligands.

既往研究显示:早在牙齿发育期,Notch1就表达于颈环星网状层的干细胞中,是其保持干细胞性质的重要机制;Notch-Delta信号还与成釉细胞、成牙本质细胞分化有关,被认为是牙齿发育细胞分化多样性的原因之一;另外,目前已明确与牙胚细胞分化有关的生长因子如TGFβ、FGF、BMPs等均可诱导Notch受、配体的表达。

However, hair follicle stem cells prefer hair destiny in vivo, unless the injury of epidimal or sytogland occurs. In 1990, Cosarelis et al. proposed "The Bulge activated hypothesis", they think the signal moleculars emit from the dermal papillar induce the downward migration and differentiation of hair follicle stem cells.

然而,体内正常情况下毛囊干细胞首先向毛发谱系定向分化,只有在表皮或皮脂腺受到损伤时,它们才进行程序重组而向表皮或皮脂腺方向分化。1990年,Cosarelis等提出毛囊的&隆突激活假说&,认为来源于毛乳头的信号因子触发了毛囊干细胞向下迁移并分化,从而维持了毛发周期的正常循环。

During the early growth stage of seedlings, basal stem diameter and paripinnate number were decreased with the increasing of shade, taproot length, root : shoot ratio, total dry weight and leaf area per seedling were maximal under 37.3% NS, specific leaf area was increased with the increasing of shade, but the relative growth rate was declined. Seedlings grew fastest under 0.6% NS, suggesting that nutrients stored in seeds played an important role at the early growth stage. The treatment of 37.3% NS was best for established seedlings in seedling height, basal stem diameter, paripinnate number, rachis length, the maximum sub-leaflet number of individual paripinnate, leaf area per seedling, relative growth rate and net assimilation rate. Light intensity was positively correlated to total dry weight, and negatively to specific leaf area. The maximum of SLA was observed under 15.5% NS.

生长早期的幼苗基径和复叶数随遮荫程度的增加而降低;主根长、根冠比、总干重和单株叶面积均以37.3% NS处理最大;比叶面积随遮荫程度的增加而增大,而相对生长率则降低;幼苗株高在0.6% NS下增长最快,表明种子中贮藏的营养物质对幼苗的早期生长可能具有重要作用。37.3% NS处理对定居后绒毛番龙眼幼苗的生长最有利,幼苗的株高、基径、复叶数、叶轴长、复叶最多小叶数、单株叶面积、相对生长率和净同化率均在37.3% NS处理下获得最大增长;幼苗总干重随光照强度的减弱而降低;比叶面积在15.5% NS处理时最大。

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