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The possible inuence of mainly immunological risk factors early after transplantation leads to manifestation of CAN in a shorter period. 4. The study showed no impact of C4d expression on mean serum creatinine levels at the time of biopsy and during 1-year observation. More patients with peritubular C4d deposition lost their grafts during the study period. 5. Deficiency syndrome-type with CAN usually are spleen-kidney Qi deficiency and hepatic and renal Yin deficiency; Sthenia syndrome with CAN usually are syndrome of blood stasis and damp-heat syndrome

并且发生CAN时间早于阴性组;体液免疫因素在慢性移植物肾病早期可能是一个重要危险因素;4、两组的肌酐水平在穿刺时及穿刺后1、3、6、12月没有统计学意义,但C4d阳性组穿刺后1年内失功率高且预后差;5、慢性移植物肾病患者的中医证型特点是本虚标实;本虚主要是脾肾气虚、肝肾阴虚,标实主要是血瘀、湿热。

Deficiency could lead to sthenia syndrome,whereas sthenia syndrome also causes deficiency,generating a vicious circulation.Muddy stasis as the pathologic products,obstruct in renal collateral throughout the whole disease course.

其中瘀浊内停为本病的病理产物,瘀阻肾络可见于本病的全过程,从丹参用药占51.8%显而易见,且用药最多的前22种药物中,活血化瘀通络之药竞占11种。

Nevertheless, According to Kaplan-Meier analysis, the 1-year graft survival rate was signicantly worse in the C4dgroup(62.9%) than in the C4dgroup (83.3%; log-rank P=0.038).(5) The distribution of deficiency syndrome as follows: spleen-kidney Qi deficiency (53.2%), hepatic and renal Yin deficiency (28.6%), spleen-kidney Yang Deficiency (18.2%). The distribution of sthenia syndrome as follows: syndrome of blood stasis(58.4%), damp-heat syndrome(20.8%), pathogenic damp(11.7%).

应用Kaplan-Meier法观察移植肾穿刺后的生存曲线,log-rank比较两组的移植肾生存率,P=0.040,两组穿刺后生存率差异具有统计学意义。6、观察77例慢性移植物肾病中虚证分布情况:脾肾气虚占53.2%,其次是肝肾阴虚占28.6%,脾肾阳虚占18.2%,而没有观察到阴阳两虚患者;实证分布情况:血瘀证占58.4%,其次是湿热证占20.8%,湿浊证占11.7%和水气证占7.8%,没有观察到风动证。

Results: After distinguishing the syndromes of the EMS patients according to traditional Chinese medicine theory, it is discovered that in the sthenia syndrome group, the ratio of CD4+/CD8+ is higher than that of control group, these variations in the kindeny deficiency blood stasis group, the variation of the ratio of CD+4/CD+8 is ,more significant than that of the sthenia syndrome group, Besides, the percentage of B cells and IL-2R+ cell and concentration of TNF-α are highr than that of the control group.

结果 以气滞血瘀、寒凝血瘀、湿热瘀阻三组组成的实证组CD+4/CD+8值升高,而肾虚血瘀组除此变化外,B、IL-2R+细胞百分率增高,外周血及腹腔液TNF-α浓度也显著增高。

It proved that "Removing-blood-stasis sticker" stimulated the points with absorption and metabolism of the medicine to develop point-meridian affection and pharmacological action.

这表明本研究"化瘀贴"是通过药物的吸收、代谢对穴位产生刺激而发挥穴位—经络效应及药物的药理作用。

Results The percentage of special diathesis type increased in the group with positive family history of keloid. The percentage of wet-heat or blood-stasis and special diathesis type increased respectively in the group with keloid on the chest and submaxilla area or on the limbs; The percentage of wet-heat type increased in the group with conspicuous inflamed keloid; The percentage of wet-heat or phlegm-wetness type increased respectively in the group with acne correlated keloid or acne uncorrelated keloid.

结果:瘢痕疙瘩有家族史者偏颇为特禀质的百分比增加;胸部、下颌部受累者偏颇为湿热质的百分比增加,四肢部受累者偏颇为瘀血质、特禀质的百分比增加;炎症明显者偏颇为湿热质的百分比增加;与痤疮相关者偏颇为湿热质的百分比增加,与痤疮不相关者偏颇为痰湿质的百分比增加。

KEY WORDS chronic fatigue syndrome; symptom complex; blood stasis due to qi deficiency

关键词]慢性疲劳综合征;证候;气虚血瘀

Yi Shen Granule can enrich qi , nourish yin, remove blood stasis and clear away turbidness.

中医理论认为,CRF的发生与虚、浊、瘀毒交结关系密切。

The results attested that Yi Shen Granule has the functions of enriching qi , nourishing yin, removeing blood stasis and clearing away turbidness.

增强机体耐力、抗应激能力、非特异性免疫功能和体液免疫功能,减轻机体因受外界因素刺激而加重病情的程度。

A better individual non-produced in a reproducing process was named as stasis of population upgrowth.

提出用种群发育停滞代数对变异概率和变异位数进行动态控制的改进遗传算法。

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As she looked at Warrington's manly face, and dark, melancholy eyes, she had settled in her mind that he must have been the victim of an unhappy attachment.

每逢看到沃林顿那刚毅的脸,那乌黑、忧郁的眼睛,她便会相信,他一定作过不幸的爱情的受害者。

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