查询词典 splenic

Objective To evaluate the feasibility and clinical results of retroperitoneal splenic autotransplantation in treatment of severe splenic injury.

目的 探讨自体腹膜后带蒂脾移植在严重脾外伤保脾手术中应用的可行性及价值。

Methods A total of 216 healthy Kunming mice were randomized into splenic tissue autotransplantation+VEGF group, splenic tissue autotransplantation group and sham operation group.

采用216只昆明种小白鼠随机分为脾切除自体脾组织移植组和假手术组，再将脾移植组分为实验组和对照组。

Objective To investigate the effects, the feasibility and the mechanism of exogenous VEGF on vascular regeneration and reconstruction of the splenic tissues during the process of splenic autotransplantation into the greater omentum.

目的 探讨应用外源性VEGF促进自体脾组织移植后血管再生与结构重建的影响，为VEGF用于自体移植脾组织的实验研究和临床应用提供理论参考依据。

Results In the medium and high dose F0 groups, it was observed that the atrophy and incrassation of seminiferous tubule, decrease of spermatogenesis, hyperplasia of interstitial tissue, especially in high dose groups spermatozoon abnormality and nucleolus concentration in the rats testis after DU ingestion for 14 months. The changes became more severe with the prolongation of DU ingestion. Such changes occurred in filial rats (F1) after DC ingestion for 5 months. In the medium and high dose F0 groups, it was observed that a little atrophy of kidney glomerulus, hyperplasia of interstitial tissue after DC ingestion for 14 months, and kidney glomerulus fibrosis happened after DC ingestion for 20 months, such changes occurred in filial rats (F1) after DC ingestion for 5 months In the medium and high dose F0 groups, splenic germinal center and periarterial lymphatic sheaths were hyperplasia , companies with lymphopoiesis after DC ingestion for 7 months, splenic white pulp became more small and sparse after DC ingestion for 20 months.

结果 F0代的中、高剂量组大鼠摄入贫铀14个月后可见雄性的精曲小管萎缩，管壁增厚呈空虚网状，生精细胞层次减少，间质细胞增生，但仍见有精子生成；高剂量组可见到精子呈异型性改变，细胞核浓缩深染，且随着摄入时间延长改变愈趋明显；F1代大鼠摄入贫铀5个月后就有上述改变且更为严重。F0代中、高剂量组大鼠摄入贫铀14个月后肾小球轻度萎缩，间质增生明显，20个月时肾小球萎缩纤维化；F1代大鼠摄入贫铀5个月后就有上述改变。F0代中、高剂量组摄入贫铀7个月时脾脏生发中心和淋巴鞘增生，淋巴母细胞增生活跃，20个月时脾小体减少，生发中心稀疏；F1代大鼠摄入贫铀早期和晚期有类似改变。F0和F1代高剂量组摄入贫铀早期肝脏有炎症细胞浸润，晚期骨髓有核细胞减少，脂肪细胞增加。

Results On day 7, 15, 30 after injection with exogenous VEGF, the mice in VEGF group were found more renascent blood vessels, splenic corpuscles, central arteries and peripheral lymphatic sheathes in the autotransplanted splenic tissues than the control group, and eventually formed more integral structure of white pulp, marginal zone and red pulp with much less fibrous tissue, while on day 60 there was no significant difference between VEGF group and the control group.

结果术后7、15、30 d注射VEGF组注射VEGF后较对照组的血管数量明显增多；术后60 d注射VEGF组注射VEGF后与对照组各时相点的组织学特征没有明显差别；术后7、15、30 d注射VEGF组KDR面积密度值高于对照组，术后60 d注射VEGF组 KDR面密度值与对照组比较无显著差别；术后7、15、30 d注射 KDR mRNA表达阳性细胞密度高于对照组，术后60 d注射VEGF组 KDR mRNA表达阳性细胞密度与对照组比较没有明显差异。

And There was no serious complication;②In the course ofinterventional therapy, Direct portal vein angiography demonstrated vena coronaria ventriculi(100%)andgastricveins(65.26%)andvenagastricaposterior38.43%, Angiography demonstrated venacoronariaventriculi communicate esophagus varicose veins, gastric veins and vena gastrica posterior communicategastric varicose veins. vena coronaria ventriculi had only a small percentage of double vein, about30.57%. The sites of vena coronaria ventriculi arising from the portal vein, splenic vein, portosplenic junction, were found in 52.06%、27.39%、20.55% respectively.③12 extrahepaticprotosystemic shunts were found in these patients. Include gastro-nephrosshuntof 3 cases, 7 caseswere splenetic- nephros shunt and 2 cases shown recanalization of umbilical vein .④The averageportal pressure before and after the procedure were 3.87±1.82kPa and 3.64±1.14kPa in 73patients, but to the time of rebleeding, it was 3.96±0.23kPa in the 11 cases.⑤There werethree kinds of variceal outcome: disappearance (54,low degree (19).⑥Spearman logisticanalyse and ANOVAtest shown liver function class, variceal degree of the splenic necrosis area,the blood direction in portal vein before operation and remain small collateral routes were thesignificant factors concerning outcome of varices.⑦The bleeding volume and portalhypertensive gastropathy are main risk factors of rebleeding.⑧The course of livercirrhosis is the risk factor of survival and extrahepatic portosystemic shunt , fine varices are thebeneficial factors to survival.⑨During all cases'followed-up data, the 1, 2, 3, 4, 5 yearcumulative survival rates and rebleeding rates were 17.81%, 28.77%, 38.36%, 43.84%, 47.95%and93.15%,91.78%,86.30%,83.56%,80.82%respectively. Conclusion The interventional disconnection treatment for liver cirrhosis and portalhypertension was designed suitability. It rapidlycontrol bleeding,butpressure of portal vein was notobvious high, perfusion was not low .it was compared with surgery therapeutic that interventionaldisconnection treatment was safe and had a significant clinical effect to hemorrhage and preventfrom rebleeding.

结果：①术后一过性发热62例(84.9%)，腹痛腹胀48例(65.8%)是介入断流术常见的并发症，未发生严重并发症；②门静脉造影显示胃冠状静脉、胃短静脉和胃后静脉的曲张分流的出现率是100%、65.26%和38.34%；显示食管静脉曲张主要由胃冠状静脉供血，胃静脉曲张主要由胃短静脉和胃后静脉供血；胃冠状静脉大多数为单支，少数为双支，其双支的出现率分别为30.57%；胃冠状静脉开口于门静脉主干的为52.06%，开口于脾静脉主干的为27.39%和开口于门脾静脉交汇处的为20.55%；③发现胃肾分流3例，脾肾分流7例、腹膜后门腔静脉分流2例，以及CTA检查发现脐静脉开放者2例；④73例患者介入断流术前和术后平均自由门静脉压力分别为3.87±1.82kpa和3.64±1.14kpa，前后比较存在显著性差异；11例再次介入手术患者的术前、术后和复发后的自由门静脉压力分别为4.02±0.24kpa、3.82±0.25kpa和3.93±0.23kpa ，前后比较发现首次术前与术后存在显著性差异，首次术前和复发出血术前门静脉压力比较无显著性差异；⑤介入术后复查曲张静脉转归基本消失54例，轻度19例；⑥Spearman相关分析和Logistic多因素回归分析，肝功能分级、静脉曲张程度、门脉血流方向和残存小侧支四个因素对曲张静脉转归有影响；Spearman相关分析和Logistic多因素回归分析门脉高压性胃病和出血量等因素对复发出血时间有影响；⑦COX回归分析，门体分流和曲张静脉转归两个因素对术后生存有影响；⑧术后随访6-70月，1、2、3、4、5年的累计复发出血率和累计生存率分别为17.81%、28.77%、38.36%、43.84%、47.95%和93.15%、91.78%、86.30%、83.56%、80.82%；结论：介入断流术治疗门脉高压食管胃底静脉曲张有独特的优点，可以快速直接控制曲张静脉出血而门静脉压力无显著增高，保证了肝脏灌注；与外科分流术相比适应证广、损伤轻、术后恢复快，不易遗漏曲张静脉；肝功能分级、曲张静脉程度、门脉血流方向和残存侧支血管对食管胃曲张静脉转归有影响；门脉高压性胃病对复发出血时间有影响；门体分流和曲张静脉转归对生存时间有影响。

These cases included 55 cases of ITP,33 cases of HS,5 cases of MA,5 cases of PHT with splenic function accentuation,3 cases of splenic cyst,1 case of splenic abscess,3 cases of splenic angioma,2 cases of splenic angiolymphoma,2 cases of accessory spleen,and 1 case of splenic rupture.

病例构成为原发性血小板减少性紫癜(idiopathic thrombocytopenic purpura，ITP)55例，遗传性球形红细胞增多症（hereditary spherocytosis，HS）33例，地中海贫血(mediterranean anemia，MA)5例，肝硬化门脉高压脾亢5例，脾囊肿3例，脾脓肿1例，脾血管瘤3例，脾淋巴管瘤2例，副脾2例，脾破裂1例。

At present,most of studies of apositia began at first to adopt animal model of splenic asthenia,there are many patterns of syndrome of apositia in the clinical practices,the model of splenic asthenia cannot represent all the models of apositia.

目前研究厌食的动物模型大都直接采用脾虚动物模型，临床上厌食症的中医证型不一，例如有脾失健运、脾胃虚弱、胃阴不足、虚实夹杂等证型，脾虚只是其中证型之一。

Objective:To approach splenic asthenia proportion in asthma acute stage and the characteristic of symptom-complex of splenic asthenia in order to provide reference evidence for clinic practice.

目的：探讨脾虚在哮病急性期各证型中的构成比及脾虚的中医证候学特点，为临床治疗提供一定参考依据。

The mainsyndromes are asthenic splenic qi and asthenia renal qi, and bloodstasis, phlegmatic retention, tuebid substance are the main pathology products,and the methods of curing are to strengthen the splenic qi, renal qi andremoving dampness and promoting diuresis, etc.

另外不同的地区由于自然地理、地域气候特点，使糖尿病肾病的临床表现产生了差异，因此在治疗上也应该兼顾这些(来源：AB0fC论文网www.abclunwen.com)特点，体现在用药上就是因地制宜、因人而异。

As she looked at Warrington's manly face, and dark, melancholy eyes, she had settled in her mind that he must have been the victim of an unhappy attachment.

每逢看到沃林顿那刚毅的脸，那乌黑、忧郁的眼睛，她便会相信，他一定作过不幸的爱情的受害者。

Maybe they'll disappear into a pothole.

也许他们将在壶穴里消失