查询词典 sperm receptor

Pig oocytes cultured in vitro for some time were inseminated by frozen–thawed ejaculated sperm. At specified times after insemination, sperm penetration, cell cycle progression and mitogen-activated protein kinase phosphorylation were evaluated. It was shown that:(1) oocytes at various maturational stages could be penetrated by sperm;(2) sperm penetration did not affect meiotic cell cycle progression;(3) sperm penetration of germinal vesicle oocytes and maturing oocytes did not alter MAPK phosphorylation; and (4) when premetaphase I and metaphase I oocytes, in which MAPK was activated, were fertilised, no evident MAPK dephosphorylation was detected as in metaphase II oocytes.

不同成熟阶段的猪卵与精子融合后体外培养发现：(1)不同成熟阶段的猪卵母细胞都可被精子穿透；(2)精子穿透不影响减数分裂细胞周期进程；(3)精子穿透GV期卵母细胞和正在成熟的卵母细胞不改变MAPK磷酸化：(4)已受精的前中期I和中期I卵母细胞的MAPK有活性，MAPK不像MII卵母细胞那样受精后发生磷酸化。

Glycine receptor competitive antagonist partially reversed the effects of propofol. When slices were preincubated with GABA〓 receptor and glycine receptor competitive antagonists collaterally or preincubated with GABA〓 receptor incompetitive antagonist and glycine receptor competitive antagonist collaterally, 100μM propofol still decreased the amplitude of EPSCs.

2在膜钳制电压为-70mV条件下，100M丙泊酚明显降低合用GABA〓受体和甘氨酸受体竞争性拮抗剂预孵的大鼠海马脑片CA1区电刺激诱发的EPSC幅值，下降程度小于单纯甘氨酸受体竞争性拮抗剂预孵组，大于单纯GABA〓受体竞争性拮抗剂预孵组；而且，100M丙泊酚更是明显降低合用GABA〓受体非竞争性拮抗剂和甘氨酸受体竞争性拮抗剂预孵的大鼠海马脑片CA1区电刺激诱发的EPSC幅值，下降程度甚至大于单纯甘氨酸受体竞争性拮抗剂预孵组。

By using two color FISH with one euchromosome probe and one sex chromosome probe, the sperm with same color of two hybridization signals in one sperm head could be identified as aneuploidy sperm or diploid sperm.

若用1条常染色体探针和1条性染色体探针进行FISH，可以区别头部有2个相同颜色荧光杂交信号的精子属非整倍体精子或二倍体精子。

The sperm treated with trypsin, plasmin, pepsin and succinic acid sodium respectively, only trypsin can dissociate the eupyrene sperm bundles and improve the motility of apyrene sperm synchronously, and olso only the trypsin-treated sperm have the ability of fertilization.

用胰蛋白酶、血纤维蛋白溶酶、胃蛋白酶及琥珀酸钠处理精液，仅胰蛋白酶能够在很好的溶解有核精子束的同时提高无核精子的运动性，也只有胰蛋白酶处理的精液人工授精能够得到受精卵。

Cervical mucus, semen consistency pilot test of time in the prediction of ovulation election period, a drop of glass on the first and fresh semen, cervical mucus and then take a drop of semen on the next, distance 2,3 mm, not to coverslip pressure to hand light light rock slide, so that two drops of liquid close to each other, under the microscope to observe sperm penetration capacity, such as the sperm can move through the mucus and to continue to run that sperm motility and cervical mucus of the characters are normal, mucus-free anti - sperm antibodies.

宫颈粘液、精液相合试验试验时间选在预测的排卵期，在玻璃片上先放一滴新鲜精液，然后取子宫颈粘液一滴放在精液的旁边，距离2、3mm，不要盖玻片加压，以手轻轻摇动玻片，使两滴液体互相接近，在显微镜下观察精子的穿透能力，如精子能穿过粘液并继续向前运行，表示精子活动力及宫颈粘液的性状都正常，粘液中无抗精子抗体。

Although the intact-receptor based biosensors of the maxillary palp of cockroach Periplaneta Americana are not yet practical analytical devices at present. Yet, sensitive and selective responses to biomolecules involving amino acids and protein, as well as some simple substance such as salts and sugars have been firstly obtained. It is already evident that receptor based biosensors are enormously superior to isolated receptor biosensors in terms of response time and recovery times, thus, the intact receptor biosensor worth of further investigation and development.

总而言之，本论文首次从电生理信号上对美洲蜚蠊下颚须的化学响应进行研究，初步探讨了基于美洲蜚蠊下颚须的整合受体生物传感器的特性；发现了美洲蜚蠊下颚须能够整合其密集的感觉毛阵列对化学刺激的响应；得到了蜚蠊对氨基酸和蛋白质等生物分子以及简单物质如盐和糖等的敏感而具有选择性的响应信号，并发现了糖和蛋白质的特殊响应信号；表明了美洲蜚蠊下颚须是一种新型整合受体生物传感器的敏感材料，进一步深入地研究信号波形及其整合原理、探寻糖和蛋白质的特殊受体细胞等，对这一类型整合受体传感器的研究发展是很有意义的。

TGF-βbinds to a heteromeric complex of type I and type II receptors. The constitutively active type II receptor phosphorylates and activates the type I receptor which phosphorylates Smad2 and Smad3 (receptor-associated Smads). Receptor-associated Smads bind the common mediator Smad4 and are translocated to the nucleus, where they associate with DNA-binding cofactors to modulategene transcription.

TGF-β与其效应细胞表面的Ⅱ型受体TβRⅡ和Ⅰ型受体TβRⅠ形成的异源二聚体结合，相继激活TβRⅡ和TβRⅠ，活化的TβRⅠ再进一步活化Smad2和Smad3，磷酸化的Smad2/3必须与Smad4结合形成复合物，才能进入细胞核，调节靶基因的转录[6]。

Erve growth factor can combine with its" receptor (one of tyrosine protein kinase receptor coded by proto - oncogene tyrosine kinase, TrkA), Causing the molecule of receptors to gather on the cell surface, and the tyrosine protein in cytoplasmic domain may be activated, three tyrosine base in the kinase domain of its" receptor and two tyrosine base at other domain be phosphated, thus, phosphated tyrosine receptor kinase became the bracket which absorb all kinds of connective proteins and kinases.

GF与其酪氨酸受体激酶受体(由原癌基因trk编码的一种酪氨酸蛋白激酶受体，TrkA)相结合，引起受体分子在细胞表面发生二聚体化，然后受体细胞内结构上酪氨酸活性被激活，使受体自身结构中位于激酶结构域的三个酪氨酸残基及在此结构域外的两个酪氨酸残基发生自身磷酸化，这样，磷酸化的酪氨酸受体激酶A便成为吸收各种连接蛋白质和酶的支架。

The pupae were exposed to 9 krad 60Co-γ rays for two days before emergence.The adults were dissected and many mature sperms could be seen in the male flies.There were no significant difference in the form,number and vigor of sperm between irradiatid and unirradiated male flies,but there were some abnormal ultrastructurail changes in the sperm of irradiated male flies such as the appearence of vacuoles in nutrient cells,disarrangement of sperms,variation of the number of chondriosome derivates,axonemes ction of formation and abnormal cell division of sperm cells.

用9krad辐照羽化前2天的蛹，成虫羽化后解剖观察，雄虫已有大量成熟精子，精子形态、数量和活力与未经辐照处理的雄虫无显著差异，但其超微结构则发生了某些异常变化，如营养细胞出现空泡、精子排列零乱、线粒体衍生体和轴丝增多或减少、构型被破坏、精子细胞分裂异常等。

Some sperm with damaged DNA may escape from the sperm surveillance mechanism and transmit the damage to the offspring.So research on the damage to sperm DNA has become one of the hot spots in reproductive medicine.

替代组蛋白成为精核蛋白的鱼精蛋白和大量的二硫键使精子染色体高度压缩，这种特化的结构可以保护精子DNA免受伤害，因此成熟精子对各种致病因素有较强的抵抗力。

Listen,point and check your answers.

听，指出并且检查你的答案。

Warming needle is one of effective treatment methods for knee arthralgia aggravated by cold,and it is simple,safety,so it should be developed in clinical acupuncture and moxibustion extensively.

但以本院科针灸门诊在2005年1月—2006年6月期间共收治膝痛患者100余例，经过临床的诊断后，其中施以温针治疗的48例，疗效显著，报道如下。1临床资料本组病例48