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Objective: The first aim of this study was to investigate bcr-abl associated T cell receptorVαand Vβgene repertoire by analyzing the restricted usage and clonal expansion of TCRVαand Vβsubfamily T cells from the normal individual peripheral blood induced bybcr-abl peptideso The second aim was to construct the idiotype TCR Vα-PIRES-TCR Vβeukaryotic vector and investigate its expression in vitro. The data will be expected toprovided the methods in development of the leukemia antigen specific cytotoxic Tlymphocyte modified by the specific TCR.

目的:通过分析bcr-abl多肽诱导正常人T细胞克隆性增殖和TCR Vα和TCR Vβ基因选用情况,获得识别bcr-abl多肽的特异性TCR基因,并构建TCR Vα和TCR Vβ双基因表达载体及分析其体外转染细胞和表达特点,从而为研制TCR转基因获得白血病抗原特异T细胞的研究提供实验依据。

The reason why specific conflicts are indissolubly tied to specific brain areas is that during our historical evolution, each part of the brain was programmed to respond instantly to conflicts that could threaten our survival.

之所以特定的冲突与特定的脑部区域有着不可分割的联系源于人类历史演变,每一部分的大脑经验式地立即做出反应程序是对危机的防卫和我们的生存的警觉。

Ginsengosides can also improve the function of both macrophagocyte and T cells, as well as promote specific Humoral Immune function and non-specific Humoral Immune function so as to kill tumor cells.

Ginsengosides还可以提高巨噬细胞功能都与T细胞,以及促进具体的体液免疫功能和非特异性体液免疫功能,从而杀死肿瘤细胞。

On the basis of the above analysis,I putforward some pieces of rational suggestion:one is changing thetraditional cognitivism to the idea of the inactive country.The other ischanging the methodics,including the application of the typical ways ofthe legistition,and adoption of the specific and certain gradation of thediscretion punishment.Chapter Seven"THE SPECIFIC ANALYSIS OF THE ALLOCATING OF THEPRESCRIBED PUNISHMENT:INTENTIONAL CRIME"

基于上述分析,我提出了完善中国刑法中法定刑幅度配置方式的合理化建议:一是认识论上的改变,即确立刑事立法上的消极国家观;二是方法论上的更新,包括典型立法方法的运用和量刑档次即罪种法定刑幅度的具体化和确定化两方面。

Many churches are becoming 'Missional' in the sense that it wants to serve very specific focus groups with specific needs.

许多教会渐渐&更宣教化&,他们试图专注于某一特殊人群,服事他们的特别需要。

There is usually little or no progression, the EMG shows non-specific myopathic features and serum CK is normal or only slightly raised.1 The muscle biopsy may show characteristic ultrastructural abnormalities but these can be difficult to detect without specific histochemistry and/or electron microscopy that were not available in 1981 when our patient was biopsied.

经常表现为缓慢或者无明显进展,EMG提示非特异性肌源性改变特征,血清CK是正常的或者仅仅轻微的升高。肌肉活检可能表现为特征性的超微结构异常,但是这些改变必须通过特异性的组织化学和/或电镜才能观察。而在患者进行活检时的1981年这些手段是达不到的。

There is usually little or no progression, the EMG shows non-specific myopathic features and serum CK is normal or only slightly raised.1 The muscle biopsy may show characteristic ultrastructural abnormalities but these can be difficult to detect without specific histochemistry and/or electron microscopy that were not available in 1981 when our patient was biopsied.

查体提示:双侧眼睑下垂,易疲劳;轻度面部及颈部肌肉无力;舌肌无力并出现中央沟。无眼肌麻痹。肩部上肢带肌消瘦、明显无力,可见肩胛翼。腰部无力,行走时脊柱前凸,呈&鸭步&步态。坐位是如不用双手辅助,可能掉出椅子外。但可以依靠其脚趾和足跟站立。患者肺活量为正常的80%,心电图及超声心动图正常。CK水平为正常的2-3倍。

OBJECTIVE ①To compare the sequences of the ribosomal rDNA-ITS2, 28S-D3 and mitochondrial mtDNA-COII in the different origins of Anopheles minimus for detecting the intra-and inter-specific variation of the sibling species of the Minimus Complex;②To reconstruct phylogenetic trees of the Minimus Complex and Myzomyia Series for determining the position of An. minimus A and C;③To establish specific methods for differentiation of two sibling species, An. minimus A and An. minimus C, of the Minimus Complex.

中文题名微小按蚊种群变异与分子鉴别研究副题名外文题名论文作者周水森导师汤林华研究员学科专业分子流行病学研究领域\研究方向学位级别博士学位授予单位中国预防医学科学院学位授予日期2002 论文页码总数98页关键词蚊微小按蚊馆藏号BSLW /2003 /R384 /3 目的①比较微小按蚊核糖体rDNA-ITS2、28S-D3基因和线粒体mtDNA-COII基因的序列差异,阐明微小按蚊复合体亲缘种种间和种内变异;②根据基因变异重建微小按蚊复合体及迈蚊系成员的种系发生关系,以确立微小按蚊亲缘种变异的种系地位;③建立微小按蚊复合体亲缘种A和C的分子鉴别方法。

At present, the study on NSCs has been gotten delightfully. But how to induce the NSCs to the specific neuron or specific neuroglial cell efficiently need to be studied further.

目前神经于细胞研究已经取得了可喜的进展,但如何高效地诱导神经干细胞分化为待定递质类型的神经元或特定类型的神经胶质细胞有待进一步研究。

Acupuncture "Zusanli"(ST36) right at the time of the introduction - hub - news-axis can be summed up as follows:to stimulate the adoption of a specific pathway,upload it to the brain limbic system specific functions excited nuclei,and then through the neurohumoral mechanism of the serum gastrin level in order to regulate the physiological functions of target organs.

针刺右侧足三里穴时的传入-中枢-传出轴可以概括为:刺激通过特定传导通路,上传到大脑兴奋边缘系特定功能核团,进而通过神经体液机制影响血清胃泌素水平,以此来调节靶器官的生理功能。

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It has been put forward that there exists single Ball point and double Ball points on the symmetrical connecting-rod curves of equilateral mechanisms.

从鲍尔点的形成原理出发,分析对称连杆曲线上鲍尔点的产生条件,提出等边机构的对称连杆曲线上有单鲍尔点和双鲍尔点。

The factory affiliated to the Group primarily manufactures multiple-purpose pincers, baking kits, knives, scissors, kitchenware, gardening tools and beauty care kits as well as other hardware tools, the annual production value of which reaches US$ 30 million dollars.

集团所属工厂主要生产多用钳、烤具、刀具、剪刀、厨具、花园工具、美容套等五金产品,年生产总值3000万美元,产品价廉物美、选料上乘、质量保证,深受国内外客户的青睐

The eˉtiology of hemospermia is complicate,but almost of hemospermia are benign.

血精的原因很,以良性病变为主。