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Intravoneous injection of 0.5mg/kgBW jingsongling cause the 60 minutesrelaxation of goat gastric motor.The effects of jingsongling on the gastric motor ofgoat is major of effects of α2 -adrenoceptor agonist,as well as that of α1 -adrenoceptor agonist,the effects of α1 -adrenoceptor agonist concentrate at thecardic and pylorus;the function of α2 -adrenoceptor exit widely at cardic,pylorus,rumen,reticulum,omasum and abomasum,the function at different part is not the same.The lowestdose of jingsonglinginhibiting the amplitude and frequency of the gastricmyoelectric is 0.01mg/kgBW;the influence of jingsonglingto the gastricmotility of goat is dose-dependent,and the amplitude regain after the frequency ofgastric myoelectriv wave.When the goat revived,the gastric motor function is notreach the level of the normal;the major reason ofjingsongling cause the goat gastricrelaxation is the amplitude renew slowly.The intravoneous injection ofjingsonglingfirst,after 5 minutes,intravoneous injection the antagonist,the effect of prazosin and idazoxan mixed is best,which can fast reversal of theinhibition of jingsongling on the gastric motor of goat,the effects of idazoxan isgood,and the prazosin block the effection of jingsongling is better than that ofxylazine,especially at cardia and pylorus.When intravoneous injection of0.5mg/kgBW idazoxan and/or prazosin only,the amplitude of gastric myoelectric ingoat increases at a certain degree,but the frequency is not changed.

静脉注射0.5mk/kgBW的静松灵引起山羊胃蠕动弛缓长达60分钟；静脉注射0.5mg/kgBW的静松灵对山羊胃蠕动机能的影响是以α2肾上腺素受体作用为主的，兼有α1肾上腺素受体的作用，而且静松灵的α1肾上腺素受体的作用主要集中在幽门和贲门；α2肾上腺素受体的作用广泛存在于贲门、瘤胃、网胃、瓣胃、皱胃和幽门中，不同部位间有功能上的差异；静注0.01mg/kgBW的静松灵是对山羊的贲门、瘤胃、网胃、瓣胃、皱胃和幽门的肌电波频率和振幅均产生影响的最低剂量；静注一定剂量的静松灵对山羊胃蠕动的抑制作用与剂量呈相关性；而且山羊胃肌电波振幅的恢复比肌电波频率的恢复慢；苏醒时山羊的胃蠕动机能尚未恢复到正常状态；静松灵引起山羊胃弛缓的主要原因是由于胃肌电波的振幅恢复慢；静注0.5mg/kgBW的静松灵，5分钟后静注0.5mg/kgBW的拮抗剂时，咪唑克生+哌唑嗪的作用最好，能迅速地逆转静松灵对山羊胃蠕动的抑制作用，咪唑克生也有很强的拮抗作用，而哌唑嗪对静松灵的拮抗效果好于对隆朋的拮抗；单独静注0.5mg/kgBW的咪唑克生和/或哌唑嗪时，山羊的瘤胃、网胃、瓣胃、皱胃、贲门和幽门的肌电波振幅有一定程度的增强，而肌电波频率未见变化。

objective to observe the antitumor activities of different solution extracts of plumbago zeylanica l.in vitro.method mtt method was used to detect the inhibitory effects on four kinds of cancer cells.results chloroform extracts had significant inhibitory effects on the breast cancer cell(bre-04),the nerve cancer cell(n-04) and the lung cancer cell(lu-04),ic50 were 0.2699mg/ml and 0.2634mg/ml,0.4961mg/ml respectively.ic50 of chloroform extract on the hepg2 was 0.9379mg/ml.ic50 of petroleum ether extracts on bre-04,n-04,lu-04 and hepg2 was 0.5902mg/ml,0.5725mg/ml,0.7938mg/ml,0.6374mg/ml;ethyl acetate extracts had fairly inhibitory effects on the lu-04,ic50 was 0.7343mg/ml;n-butanol extracts and water-solubility extracts had notsignificant inhibitory effects on the four kinds of cancer cells.conclusion the antineoplastic effective parts of plumbago zeylanica l.were chloroform and petroleum ether extracts.

目的 探讨白花丹体外抗肿瘤作用的活性部位。方法 mtt染色法对白花丹五种溶剂提取物体外抗肿瘤活性进行了初步的研究。结果氯仿提取物对乳腺癌细胞（bre-04）、神经癌细胞（n-04）、肺癌细胞（lu-04）有较好的抑制生长作用，ic50分别为0.269 9 mg/ml、0.263 4 mg/ml、0.496 1 mg/ml，对肝癌细胞hepg2抑制作用差， ic50为0.937 9 mg/ml；白花丹石油醚提取部位对乳腺癌细胞（bre-04）、神经癌细胞（n-04）、肺癌细胞（lu-04）、肝癌细胞hepg2的ic50分别为0.590 2 mg/ml、0.572 5 mg/ml、0.793 8 mg/ml、0.637 4 mg/ml；乙酸乙酯提取物对肺癌细胞（lu-04）有一定的抑制作用，ic50为0.734 3 mg/ml；水溶性提取物以及正丁醇提取物无明显抑制肿瘤作用。结论白花丹氯仿提取部位、石油醚提取部位体外抗肿瘤作用较好，值得对其提取部位进一步分离纯化并研究其抗肿瘤作用机制。

Multiple linear regression equation between LST and brightness temperatures of AVHRR channels 4 and 5 was almost at the significant level (p＜0.05), and the level was not improved by adding brightness temperature of AVHRR channel 3 as a regressor. Path analysis is a statistical technique that partitions correlations into direct and indirect effects, and differentiates between correlation and causation. The results of path analysis showed that the direct effects and indirect effects of brightness temperatures of AVHRR channels 4 and 5 to LST were strong, respectively, the direct effect and indirect effects of brightness temperature of AVHRR channels 3 to LST were weak. These implied the brightness temperatures AVHRR channels 4 and 5 should be involved in retrieving LST.

多元线性回归分析结果表明，土地表面温度与AVHRR第4、5波段亮度温度间的回归方程接近5％的显著水平；通径分析的结果表明，AVHRR第4、5波段的亮度温度对土地表面温度的直接作用和间接作用均较强，而AVHRR第3波段的亮度温度对土地表面温度的直接作用和间接作用均较弱，因此，在反演土地表面温度时必须同时考虑AVHRR第4、5波段的亮度温度。

The gene additive effects,dominant effects,sex-linkage effects and maternal effects of the five characters including the cocoon weight,cocoon shell weight, fibroin content and pupa weight were studied by the method of sex-linkage model in this paper.

采用性连锁模型，分析了全茧量、茧层量、丝素量、茧层率、蛹重5个性状的基因加性效应、基因显性效应、性连锁效应、母体效应以及各基因与环境互作效应的相互关系，丰富了性状间相互关系的信息。

AIM: To isolate bioactive secondary metabolites from the fruits of Schisandra rebriflora Rehd. et. Wils and study their effects on HIV-1 infectivity. METHODS: Inhibition of syncytia formation, HIV-1 reverse transcriptase and protease, protection of HIV-1 infected cells, level of HIV-1 p24 antigen,blockage of fusion were detected. RESULTS: A lignan compound, named rubrifloralignan A, was first isolated as a natural product with modest inhibition effects on syncytium formation and HIV- 1 replication and could protect HIV-1 infected cells with weak inhibition effects on fusion and RT, but it showed no effects on the replication of HIV-1 chronic H9 and PR. CONCLUSION: Rubrifloralignan A is an efficient anti-HIV-1 product with effect on early stage of HIV-1 replication.

目的：从红花五味子果实中寻找活性代谢产物，研究其抗HIV—1活性和作用机制方法：通过合胞体抑制、HIV-1感染细胞保护、HIV—1p24抗原测定、融合阻断、逆转录酶和蛋白酶活性分析等实验，检测分离化合物的抗HIV—1活性并探讨其作用机制一结果：红花五味子甲素能够抑制病毒诱导的合胞体形成，保护病毒感染细胞，抑制病毒在细胞内的复制对HIV-1感染细胞与正常CD4^＋细胞间的融合，逆转录酶活性有一定的抑制作用但是红花五味子甲素不抑制病毒在慢性感染细胞中的复制，也不抑制蛋白酶的活性、结论：首次从天然产物中分离得到红花五味子甲素，它对HIV—1病毒复制早期具有抑制作用

Based on these previous work, in this research, in order to explore the the molecular mechanism of enhanced tumor cell immunogenicity treated by elemene and mytomycin C compositely, we used murine Hca-F ascitic hepatic carcinoma ( high lymphatic metastasis substrain of H22) as an experimental model to compare the immunoprotective effects on Hca-F cells as well as the mechanism of the effects caused by HSP70-peptide complex purified from untreated tumor cells, EC-TCV and BCG; We studied the mechanism of increased tumor cell membrane HSP expression treated with elemene by the techniques of RT-PCR and immunoelectron microscopy; In order to deeply elucidate the antitumor effects and the molecular mechanism of elemene in increasing tumor cell immunogenicity we analyzed and compared the effects of elemene and heat shock on the gene expressions of tumor cell using gene expression profile chip.

本论文在上述研究成果的基础上，选择小鼠肝癌H22的高淋巴道转移亚系Hca-F为模型，进一步比较了未处理肿瘤细胞来源、榄香烯复合瘤苗来源的和卡介苗来源的HSP70-肽复合物对Hca-F的免疫保护效应、效应机制，探讨榄香烯-丝裂霉素复合处理增强肿瘤细胞免疫原性的分子机制；以Hca-F和人肝癌细胞株HepG〓等为模型研究了榄香烯处理增强肿瘤细胞膜热休克蛋白表达的机制；以HepG〓为模型用表达谱基因芯片研究比较了榄香烯与热休克处理对肿瘤细胞基因表达的影响，从而进一步阐明榄香烯抗肿瘤作用及增强肿瘤细胞免疫原性的分子机制。

The methods proposed by Wang et al (1999) could analyze additive effects, additive by additive epistatic effects and their interaction with environments, but could not estimate dominance effects and epistatic effects related to dominance.

Wang等(1999)的方法能够分析加性效应、加加上位性效应及其与环境的互作效应，但无法估计显性以及与显性有关的上位性效应。

The electric conductivity of solid polyiodides increases largely as the aggrandizement of polyiodide anions"polymerization degree. The solid polyiodides have excellent sterilizing effects and the effect of tetra-n-butyl ammonium undecaiodide is the best of them, and the sterilizing effects increase as the aggrandizement of polyiodide anions" polymerization degree. The sterilizing effects of resinic polyiodides increase as the aggrandizement of polyiodide anions polymerization degree, the heptaiodide resinic polyiodide has better sterilizing effects than the triiodide and pentaiodide.

固体高聚碘系列化合物的电导率随着高聚碘阴离子聚合度的增加而增加，并且增幅较大；固体高聚碘对常见细菌均具有很好的杀灭作用，并且随着高聚碘阴离子聚合度的增加，杀菌能力也随着增强，其中正四丁基十一碘化铵杀菌剂的效果最佳；树脂高聚碘随着高聚碘阴离子聚合度的增加，杀菌能力增强，碘七树脂高聚碘的杀菌效果要明显好于碘三树脂和碘五树脂高聚碘。

Monte Carlo simulations were conducted to study the new approaches of QTL mapping, the results indicated that general least squares method, which was widely applied in mixed linear model, could unbiasedly estimate all genetic main effects, including additive effects, dominance effects and epistatic effects of additive by additive, additive by dominance, dominance by additive, dominance by dominance.

对新提出的QTL分析力法进行了Monte Carlo模拟研究，结果表明，广泛应用于混合线性模型的广义最小二乘法能够无偏估计加性效应，显性效应以及加加、加显、显加、显显上位性效应等各项遗传主效应；运用线性无偏预测法能够无偏预测上述各项遗传主效应与环境的互作效应；基于QTL效应的杂种优势预测也是无偏的。

There were no significant facilitating effects to the retention of signaled information in the overuse of text signals condition, but there were in the selective use of text signals condition. Experiment 3, in which 2 small experiments contained, studied the effects of reader-based factors. Experiment 3a examined the effects of the familarity to the text topics and the readers' reading levels. Experiment 3b explored the effects of cognitive style and the intention to use the text signals. The results were as the follows: There were no significant difference between the signaled and unsignaled conditions in the circumstance of high familarity to the text topics, but there were significant differences between them in the circumstances of lower familarity to the text topics. There were no significant differences between the signaled and unsignaled conditions for the field-independent participants, but there were for the field-dependent participants. All the participants with different reading levels were helped by the text signals.

实验3 对不同主体因素条件下文章标记效应进行了研究，分2个分实验，实验3a以高中二年级学生为被试，研究了文章主题熟悉程度与阅读水平对文章标记效应的影响，实验3b以初中二年级学生为被试，探索了读者不同的认知方式与标记利用的意向对文章标记效应的影响，实验3结果发现，读者的阅读水平、对文章主题的熟悉程度、认知方式和利用标记意向等因素影响着文章标记效应，在文章主题熟悉的条件下，有无文章标记无显著差异，但在主题不熟悉条件下，有文章标记的效果显著优于无标记的效果；对场独立被试而言，有无标记无显著差异，但对场依存被试来说，有标记条件显著优于无标记条件；文章标记对不同阅读水平被试都有显著促进效应；文章标记利用意向对场独立与场依存被试都有显著促进效应。

Methods Clinical data of 3 cases of bile duct injury during laparoscopic cholecystectomy were analyzed retrospectively.

回顾总结3例LC术中胆管损伤的临床资料，分析3例胆管损伤的原因及对策。

These techniques are applied to the gobang.

本文将这些技术用于五子棋中。