查询词典 skeleton construction

The regioselectivity of primary aminyl radical cyclization was first investigated in this dissertation. The total synthesis of 14-Aza camptothecin was then achieved on the basis of our investigation in the construction of pyrimidin-4-one skeleton via [4+2] strategy.

中文摘要本论文首先探讨了伯胺氮自由基环合反应的区域选择性，然后应用[4 + 2]策略对吡咯并嘧啶-4-酮的合成方法进行了研究，并在此基础上完成了14-氮杂喜树碱的合成工作。

With L-DOPA as the starting chiral phenylalanine derivatives, construction of the skeleton of Phthalascidin was studied. Firstly, starting from L-DOPA and 3,4-dimethoxyphenylalanine, an amide 〓 was obtained, and a modeling cyclization reaction was carried out but failed to give the anticipated product.

二、对由苯丙氨酸甲酯衍生物通过Bischler-Napieralski反应合成四氢异喹啉—3—甲酯进行了研究，通过研究首次发现，生成苄基噁唑的反应是正常的B-N反应的竞争性反应，并从机理上给予了解释，所得出的结论具有一定的规律性，在杂环的合成方面具有一定的应用价值。

This thesis is aimming at the synthetic study of Cephalotaxine, construction of Stenine skeleton and consists of the following three parts:In Charpter 1 the isolation, chemical structure identification, biological activities of Cephalotaxine was described and reviewed total synthesis of Cephalotaxine via spiro compound.

本论文以三尖杉碱的合成及百部碱骨架的构筑为研究核心，共分为以下三部分内容。

In this review, basically classified by the chemical construction of dendritic skeleton, mainly focusing on the polyamidoamine, polypropylene imine, polycarbosilane, polyether and polyester systems, the recent advances in the rationally designed syntheses and their self-organized superstructure of side-chain LC dendrimers have been summarized and commented.

本文按树枝状大分子骨架的化学结构分类，对侧链型树枝状大分子液晶的设计合成、液晶相行为及其自组织超结构的最新研究进展进行总结和评述，重点介绍了聚酰胺-胺、聚丙烯亚胺、聚碳硅烷、聚醚以及聚酯树枝状大分子液晶体系。

The present dissertation reviews the total synthesis of biotin, particularly on Hoffmann-La Roche\'s Lactone-Thiolactone approach. The Lactone-Thiolactone approach is presently the most competitive commercial route, which gives an excellent illustration of the gradual construction of the functionalized skeleton with the simultaneous solution of the stereochemical issues in a minimal number of steps.In 1970, Gerecke etc. of Roche Corp.

论文对生物素全合成的文献进行了综述，重点讨论了目前工业上最有竞争力的内酯—硫代内酯路线，展示了生物素是如何以最少的步骤去逐步构建目标产物的官能团骨架并同时解决立体化学问题的。1970年，Roche公司的Gerecke等报道了一条通过手性内酯，以较高收率并保持构型得到手性硫代内酯，从而直接合成d-生物素的方法后，该中间体内酯(3aS，6aR)-1，3-二苄基。

Until the 20th cent. there were three great developments in architectural construction—the post-and-lintel, or trabeated, system; the arch system, either the cohesive type, employing plastic materials hardening into a homogeneous mass, or the thrust type, in which the loads are received and counterbalanced at definite points; and the modern steel-skeleton system.

直到20美分。有三个巨大的发展，建筑施工，后和门楣，或trabeated ，系统；拱系统，无论是一致的类型，采用塑料材料硬化成一个单一的质量，或类型的主旨，其中负载收到并在一定的平衡点；与现代钢骨架系统。

Total synthesis of CET was accomplished by two routes through a conceptually novel strategy featuring a transannular reductive rearrangement as the key transformation for the construction of the core pentacyclic ring skeleton of CET.

我们采用了全新的合成策略，以氮原子参与的跨环还原重排为关键反应，通过两条路线分别成功地合成了三尖杉碱。

China Sea from the market and the construction of two Yee Tsui Villa "soul and skeleton" positioning.

中海是从市场和建筑两个方面对怡翠山庄的&灵魂和骨架&进行定位。

As she looked at Warrington's manly face, and dark, melancholy eyes, she had settled in her mind that he must have been the victim of an unhappy attachment.

每逢看到沃林顿那刚毅的脸，那乌黑、忧郁的眼睛，她便会相信，他一定作过不幸的爱情的受害者。

Maybe they'll disappear into a pothole.

也许他们将在壶穴里消失