查询词典 silencing

In order to construct a normalized cDNA silencing library, a novel procedure was adopted to reduce the abundant copy number and increase the rare copy number. Then the normalized cDNA was put into pTRV vector to construct a cDNA library and this cDNA library was screened with the technology of virus induced gene silencing.

然后把均一化之后mRNA反转录得到cDNA，再与基因沉默载体pTRV重组，最后把构建好的载体通过电转化的方法转入到GV3101农杆菌中，从而建立起破色期番茄果实均一化cDNA沉默文库。

The results indicated that RNA silencing of Waxy gene resulted in low level of amylose in the seeds of transgenic wheat.

研究结果表明Waxy基因的RNA沉默使转基因小麦种子直链淀粉的含量下降。

The results indicated that RNA silencing of Waxy gene resulted in low levels of amylose in the seeds of transgenic wheat.

研究结果表明Waxy基因的RNA沉默使转基因小麦种子直链淀粉的含量下降。

Methylation of CpG islands in the promoters induces gene silencing. The multiple tumor suppressor gene P16, located at chromosome 9p21, regulating normal proliferation of cells with a functional unit constituting of p16, cyclin D1 and pRb together. Methylation of P16 gene has been detected in several lymphocytic and plasmacytic malignancies such as lymphoma, acute lymphocytic leukemia and multiple myeloma and shows relationships with the pathogenesis of these diseases. Application of demethylation agents or arsenical to refresh the gene functions will be expected to be a new treatment for hemopoietic malignancies.

基因启动子区CpG岛甲基化常导致基因沉默。P16基因是一定位于9p21的多种肿瘤抑制基因，通过pl6INK4Acyclin D1-PRb通路维持机体细胞的有序增殖。P16基因甲基化在淋巴瘤、急性淋巴细胞性白血病、多发性骨髓瘤等多种淋巴细胞浆细胞肿瘤中被检测到，并与疾病的发生、发展存在一定关系，应用甲基化抑制因子或砷剂去甲基化治疗，恢复基因功能可望成为血液恶性肿瘤治疗的一种新手段。

RNA interference represents a common biological phenomenon of double-stranded RNA mediated post-transcriptional gene silencing, which lies in altitude plants and animals. The mechanism of this process is described as that: the dsRNA in cells are cut into double-stranded small interfering RNA. By joining with an effector complex termed RISC (RNA-induced silencing complex), siRNA binds to the cellular RNA with homologous sequences, and contributes to the degradation of the corresponding mRNA, the inhibition of specific gene expression.

RNAi技术是双链RNA(double strand RNA，dsRNA)介导的序列特异性的转录后基因沉默，广泛存在于高等植物和动物中，其机制是细胞内的dsRNA被Dicer剪切成双链的小分子干涉RNA (small interfering RNA，siRNA)与RNA诱导的基因沉默复合物结合，降解与之互补的靶mRNA，特异性抑制靶基因表达。

It is important to study mechanism of transgene silencing and adopt effective strategies to overcome transgene silencing.

因此，探讨转基因失活的机制，进而采取有效的策略防止失活现象是一项十分有意义的工作。

Silence, Strangulate, Silencing Shot, and Arcane Torrent: These abilities will also apply a 3 second interrupt effect against non-player controlled targets, making them more versatile against creatures immune to silencing effects.

沉默射击等：这些技能现在同时使非玩家目标处于3秒"打断"状态，以使这些技能对无法沉默的目标也能起作用。

Marks, it's just Aimed shot, arcane shot, silencing shot, multishot, arcane shot, autoshot gg (switching the order if the lock sees me first to arcane shot, silencing shot so he cant stop my aimed shot, and so on).

作为射击猎人，只需要瞄准，奥射，沉默射击，散射，奥射，自动射击如果术士先发现你就变换顺序奥射，沉默射击以免他阻止你瞄准射击等等）。

To those who cling to power through silencing corruption and deceit and the silencing of dissent, know that you are on the wrong side of history; but that we will extend a hand if you are willing to unclench your fist.

导者：你的人民评判你的依据是你建立了什么，而不是破坏了什么。导者：你的人民评判你的依据是你建立了什么，而不是破坏了什么。

Theresults show that the tempreture changes can affect the growth of the transgenic cotton and theexpression of the Bt insecticidal gene and therefore affect the timing and the onsetting of thetransgene silencing. The time of the occurrence of silencing is more earlier after hightemperature treatment.

结果表明，温度变化影响抗虫棉早期的生长发育和Bt杀虫基因的表达，从而影响Bt杀虫基因沉默的发生时间，前期高温处理可使Bt杀虫基因在生长发育期中的沉默时间提前。

In the United States, chronic alcoholism and hepatitis C are the most common ones.

在美国，慢性酒精中毒，肝炎是最常见的。

If you have any questions, you can contact me anytime.

如果有任何问题，你可以随时联系我。