查询词典 signalling

Ultimately, vulnerable groups of neurons atrophy and die in a process that may involve excitotoxicity (overstimulation of neurotransmitter receptors on neuronal surface membranes), collapse of calcium homeostasis, inflammation, and depletion of energy and growth factors. A form of apolipoprotein E, apoE4, contributes to the abnormal accumulation of A and tau, but probably also damages mitochondria and the cellular cytoskeleton. A , tau, apoE and -synuclein interact with many other molecules and modulate diverse signalling cascades that regulate neuronal activity and survival.

最后，易感神经元会萎缩直至死亡，原因可能有兴奋性中毒（神经递质对神经元表面受体的过度刺激引起），钙稳态失衡，炎症反应，能量和生长因子的耗尽。apoE4的产生可导致A肽和tau蛋白的异常聚合，可能也损害线粒体和细胞骨架。A肽、tau蛋白、apoE和突触核蛋白可与很多分子反应，也可调节不同信号级联反应，这些级联反应对于维持神经元活动性和生存性意义重大。

To examine the influence of systemic factors on aged progenitor cells from these tissues, we established parabiotic pairings (that is, a shared circulatory system) between young and old mice, exposing old mice to factors present in young serum. Notably, heterochronic parabiosis restored the activation of Notch signalling as well as the proliferation and regenerative capacity of aged satellite cells.

为了查明系统因子对来自这些组织的衰老祖细胞的影响，我们在幼鼠和老鼠之间建立了共生态配对试验（即：一种共享的循环系统），给老鼠输入含有年轻因子的血浆，奇怪的是，异时性共生态细胞Notch信号重新激活，同时恢复了衰老干细胞增生和再生能力。

China's market for rail equipment, including trains, components and equipment such as signalling systems, is expected to quintuple from an average of $10bn a year between 2004 and 2008 to more than $50bn between 2009 and 2013, according to McKinsey.

据麦肯锡预测，中国铁路设备市场的规模，将在2004至2008年年均100亿美元的基础上增加4倍--在2009至2013年间达到年均逾500亿美元。

Opium production has expanded hugely, especially in the Taliban's southern heartland, signalling a risible failure for the British-led attempt to end it.

鸦片产量急剧增加，尤其是在塔利班南部的心脏地区，这也标志着英国领导的试图根除鸦片的行动令人可笑的失败了。

Here we report the use of a library of Drosophila strains expressing inducible hairpin RNAi constructs to study the Notch signalling pathway during external sensory organ development.

在本研究中，研究小组构建了一个RNAi文库，研究果蝇外部感官器官发育的Notch信号通路。

First, it has a signalling function.

首先，它有一个信号的功能。

No, no, he said that much I could understand before signalling that I should stand up.

不，不，他说——我能理解的就这么多——然后示意我应该站起来。

The main advantage of this cable is, that there are two signalling lines in each direction.

这种电缆主要的好处是，在每个方向上有二个信号线路。

So, when you think you are feeling hungry, your body may in fact be signalling to you that you are thirsty!

因此，当你认为你觉得很饿的时候，实际上你的身体可能发出的信号是你渴了！

It was necessary to have a special security design for safety computer in signalling equipments.

必须对信号设备的安全计算机进行专门的选型与设计。

I didn't watch TV last night, because it .

昨晚我没有看电视，因为电视机坏了。

Since this year, in a lot of villages of Beijing, TV of elevator liquid crystal was removed.

今年以来，在北京的很多小区里，电梯液晶电视被撤了下来。