查询词典 signaling

The serum- and glucocorticoid- inducible protein kinase is an early transcriptionally stimulated gene. The signaling pathway through SGK1 may play an important role in initiation of diabetic nephropathy.

血清-糖皮质激素诱导型蛋白激酶是一种快速诱导型蛋白激酶，可能参与了糖尿病肾病的发生和发展。

The results in this study provided a clue to explore the role of GNMT in tumorigenesis and the mechanism of the cytoplasm to nucleus translocalization of ARRB1 in GPCR signaling.

本文的结果为揭示GNMT的抑癌机制以及ARRB1在GPCR信号通路中的入核机制提供了新的线索。

Plant disease resistant reaction is a complex physiological process. To date, it has been found that many compounds are involved in the recognition of pathogens and following signaling transudation pathways.

中文题名水稻抗稻瘟病数量性状相关基因的鉴定与分析副题名外文题名 Identification and characteristics of quantitative trait loci associated genes resistant to rice blast disease in rice 论文作者郑先武导师朱立煌研究员学科专业遗传学研究领域\研究方向学位级别博士学位授予单位中国科学院遗传与发育生物学研究所学位授予日期2002 论文页码总数77页关键词水稻抗病基因稻瘟病馆藏号BSLW /2003 /S511 /97 植物对外界病原的抗性过程是一个复杂的生理现象。

Results Of the 560 genes, 177 were homologous to the Aspergillus fumigatus, Aspergillus nidulans, Neurospora crassa and Trichophyton rubrum in NR database. Some important genes and signaling pathways, which might be related to the induction of condial germination, sere found.

结果 在孢子中的560个基因中，有177个与烟曲霉、构巢曲霉、粗糙链孢菌和红色毛癣菌4类线性真菌基因有同源性，并发现一些可能参与孢子萌发的重要基因及相关的调控途径。

In the trunked system,(23,12) Golay code transfering signaling has a minimum distance of seven,so it has very strong error-correcting capability .

集群通信系统中用来传送信令的(23，12)Golay码最小距离为7，具有较强的纠错能力，译码采用伴随式译码。

Furthermore, the network was searched for interactions linking uncharacterized gene products and human disease proteins to regulatory cellular pathways. Two novel Axin-1 interactions were validated experimentally, characterizing ANP32A and CRMP1 as modulators of Wnt signaling.

作者们进一步分析了这个网络里面未知功能的蛋白和跟疾病相关蛋白与细胞调控通路的关系，发现了两个新的Axin-1相互作用并被实验证实，及ANP32A and CRMP1在Wnt信号通路里的调控作用。

In this thesis, we find that dlg is indispensible in the establishment of anterior-posterior and dorsal-ventral polarity of drosophila oocyte. Removal of Dlg function from the posterior follicle cells using the FLP/FRT system leads to disruption of oocyte skeleton reconstruction that is elicited by the failure of those posterior cells to differentiate normally in mid-oogenesis. We demonstrate that abnormity of Notch, JAK-STAT and EGFR signal pathway in dlg mutants contributes to this aberrant differentiation. dlg null mutant also blocks the normal differentiation of two groups of anterior follicle cell-stretched cell and centripetal cell, but not border cell, with a lower penetrance. However unlike the result in posterior follicle cells, Notch and JAK-STAT signaling are both undisrupted in all mutant anterior follicle cells, implying other fate determinants may be involved.

我们的研究发现，后端滤泡细胞中的Dlg在果蝇卵子发生中期卵母细胞前后轴和背腹轴建立过程中也是必须的，PFC中dlg完全缺失型突变引起PFC的分化异常，导致卵子发生中期卵母细胞骨架重组异常，Stau、Grk等极性决定蛋白定位错误。dlg突变阻碍了Notch、JAK-STAT、EGFR等调节PFC分化的信号通路的激活。dlg突变的PFC也没有获得前端滤泡细胞命运。dlg突变不影响前端滤泡细胞群中边界细胞的分化，但是在一定程度上影响伸展细胞和向心细胞的分化，并且这种影响不依赖于前端滤泡细胞Notch或JAK-STAT信号激活的异常。

Recent study indicates abnormal expression and signaling pathway of the TGF-β in uveal melanoma and suggests that abrogation of control of melanocyte growth by the TGF-β may be important in the formation of uveal melanoma.

近年研究TGF-β的异常过表达以及信号传导通路的异常与葡萄膜黑色素瘤生长和侵袭转移能力密切相关。

To better understand the mechanisms of cyclic di-GMP signaling in Xanthomonas oryzae pv.

本文的目的为阐明水稻白叶枯病菌Xanthomonas oryzae pv。

Taken together, our data showed that both the CSF-box and the octamer are important for the LPS-induced G-CSF promoter activity, moreover, the activation of MEK/ERK signaling pathway is indispensible for LPS-induced G-CSF expression in RAW264.7 macrophage.. It seems that LPS-induced activation of MEK/ERK pathway does not directly regulates NF-κB transactivity, but is essential for LPS-induced Oct-2 binding to the octmaer within G-CSF promoter and transcription activation of the G-CSF expression.

透过这些结果，我们认为MEK/ERK pathway的确参与LPS活化G-CSF表现的过程，虽然MEK/ERK pathway都影响了CSF-box以及octamer对G-CSF启动子所贡献的活性，但似乎MEK/ERK pathway的下游并非直接影响NF-κB调控基因转录的活性，而主要是影响了Oct-2对G-CSF启动子的调控。

She gently rebuff ed him, but agreed that they could be friends

她婉言拒绝了，但同意作为朋友相处。

If in the penal farm, you were sure to be criticized.

要是在劳改农场，你等着挨绳子吧！