查询词典 signaling

Objective: to investigate the mechanism about the effect of danshensu on the transforming growth factor beta 1 signaling pathway in Rattus norregicus hepatic stellate cells .

以肝星状细胞株HSC-T6为研究对象，免疫细胞化学法观察丹参素对TGFβRII表达的影响，RT-PCR法检测丹参素对Smad2和Smad4表达水平的影响，检测结果做图像分析处理。

O-GlcNAc signaling represents a unique endogenously recruitable mechanism of cardioprotection that may involve direct modification of mitochondrial proteins critical for survival such as voltage-dependent anion channel.

O-链β-N-乙酰氨基葡萄糖信号代表一种独特的内源性的的心脏保护修复机制，其包括残存的线粒体蛋白直接修复，如电压依靠性阴离子通道

Cells were immediately fixed and processed for immuno?uorescence and tested for translocation ofβ-catenin.β-catenin and target genes of Wnt/β-catenin signaling COX-2, cyclinD1, c-fos, c-Jun mRNA expression were examined by RT-PCR. Saos-2 osteoblastic cells were co-transfected with a wild type or mutant Tcf luciferase reporter gene and Renilla luciferase plasmid. Posttransfection cells were subjected to 1 hour of 12% elongation.

作用1h、2h和4h后，用免疫荧光的方法检测β-catenin的表达和在细胞上定位的变化；用半定量RT-PCR检测β-catenin mRNA表达的变化；用质粒转染的方法检测荧光素酶报告基因Tcf转录的情况；用半定量RT-PCR检测Wnt/β-catenin通路下游基因COX-2，cyclinD1， c-fos， c-Jun mRNA表达的情况；用免疫共沉淀的方法检测β-catenin和E-Cadherin的结合情况。

We show using in vitro and in vivo models that active TGF-beta1 released during bone resorption coordinates bone formation by inducing migration of bone marrow stromal cells, also known as bone mesenchymal stem cells, to the bone resorptive sites and that this process is mediated through a SMAD signaling pathway.

我们利用体外和体内模型，发现在骨吸收过程中释放的有活性的TGF-β1通过诱导骨髓基质细胞的迁移至骨重吸收位置来调节骨形成，这一过程通过SMAD信号途径调节。

"Chemopreventive properties of Hibiscus sabdariffa L. on human gastric carcinoma cells through apoptosis induction and JNK/p38 MAPK signaling activation.

68，&生科所&，&陈璟贤&，，&助理教授&，&研究论文&，洛神花萃取物经由活化JNK/p38MAPK讯息路径诱导人类胃癌细胞凋谢死亡以达到化学预防之功效。

Derstand PG signaling pathway, PG gene was cloned from Sclerotinia sclerotiorum by RT-PCR, the encoding region of PG was

关。为了解PG 的信号转导途径，利用RT-PCR 方法克隆了核盘菌的PG 基因，将PG 的编码区与酵母GAL4 的DNA

ARC1(arm repeat containing 1 ) is a very important downstream protein factor in sporophytic self- incompatible signaling process. It is made up of arm repeat domain, U-box domain, leucine zipper domain/ coiled-coil domain, one nuclear localization signal and two nuclear export signal, arm repeat domain and U-box domain are main functional domain.

臂重复蛋白ARC1(arm repeat containing1，ARC1)是孢子体型自交不亲和信号传导途径下游非常重要的蛋白质因子，由臂重复结构域、U-box结构域、亮氨酸拉链/卷曲螺旋结构域、1个核定位信号和2个核输出信号组成，其中臂重复结构域和U-box结构域起主要功能。

Therefore, the study on mechanism of stomatal movement is theoretically and practically important for the research on signaling and plant adaptation to the environment.

因此，研究气孔运动机理对深入探讨植物对环境的适应机理以及植物细胞信号转导具有重要的理论和现实意义。

Blockage of VEGF signaling with anti–VEGF antibody reduced the growth of cultured neurons by 17% and the regeneration of subbasal neurons by 23%.

通过VEGF抗体阻断VEGF信号途径减少了17%培养的神经元的生长和23%基底下神经元在再生。

Neural stem cells exist in numerous regions of the central nevous system and have capacity to differentiate into neurons. Noggin promotes adult neurogenesis of subventricular zone and subgranular zone by blocking endogenous bone morphological protein signaling under physiologic state.

神经干细胞存在于中枢神经系统的广泛区域，且这些细胞具有分化为神经元的潜能。noggin通过拮抗内源性骨形态蛋白(Bone Morphological Protein， BMPs)的作用促进生理状态下成年动物室下区和海马齿状回成体神经元发生。

She gently rebuff ed him, but agreed that they could be friends

她婉言拒绝了，但同意作为朋友相处。

If in the penal farm, you were sure to be criticized.

要是在劳改农场，你等着挨绳子吧！