查询词典 signaling

Fibroblast growth factor signaling guides mesodermal cell migration; however, we found some directed dorsal migration in an FGF receptor mutant, which suggests that additional signals are involved.

显微元细胞增长因子信号知道着中胚层的细胞迁移；但是，研究人员发现在突变FGF受体中存在着定向的背离迁移作用，这说明有更多的信号参与到了细胞的运动当中。

ER is well characterized as a mobilizable calcium store that sequesters excess cytosolic calcium and a reservoir for calcium signaling to maintain intracellular Ca2+ homeostasis.

2钙离子的检测 1、细胞内质网是[Ca~(2+)]_i的主要储存场所，以及[Ca~(2+)]_i在细胞凋亡的信号转导通路中所具有的重要作用，本实验研究了SfaMNPV诱导SL-1细胞凋亡过程中细胞内[Ca~(2+)]_i的变化以及[Ca~(2+)]_i可能在凋亡信号转导通路中的意义。

We show that the Wnt signaling actiator 6-bromoindirubin-3'-monoxime releases MSCs from the osteoinhibitory effects of Dickkopf-1, whereas LiCl treatment does not.

我们也发现Wnt信号激活剂BIO会解除DDK1对MSC的成骨抑制作用，而LiCl处理则无这种作用。

Our results suggest that several signaling pathways are involved in regulating Tbx6 expression, and pave the route to reveal the molecular mechanism of how myogenesis is initiated.

Xnot对Tbx6早期起始以及晚期维持表达都没有影响，提示其它基因参与限制Tbx6的空间特异性表达。我们的结果揭示了可能参与调控Tbx6表达的上游基因，为进一步揭示肌肉发生起始的机制提供了研究基础。

These above results suggest that the inhibition of myogenic differentiation by hypoxia might be independent of HIF-1 signaling.

同时检测了HIF-1α在诱导分化的C2C12细胞中的定位，发现低氧没有影响HIF-1α蛋白在细胞中的分布。

We thus hypothesized that increased TGF-beta signaling may contribute to the multisystem pathogenesis of MFS, including the development of myxomatous changes of the atrioventricular valves.

研究者使用抗游离和激活型TGF-β的单克隆抗体观察到，突变型小鼠二尖瓣叶内的免疫激活性增加，&表明TGF-β的激活而不是细胞因子的生成增多&。

No data block sequence number is used in the ACK/NAK signaling.

在ACK/NAK信令中不使用数据块序号。

Polycomb group genes Psc and Su2 restrict follicle stem cell self-renewal and extrusion by controlling canonical and noncanonical Wnt signaling.

另外，突变的干细胞从基地膜一侧逐渐突出并脱离出上皮层，在异位不断增长，形成团状肿瘤组织。

Conclusions-: In adult density-gradient separated BMMNCs, canonical Wnt3a promotes stemness, proliferation, and hematopoietic commitment, whereas noncanonical signaling via Wnt11 induces robust cardiomyogenic differentiation in a protein kinase C- and c-Jun-N-terminal kinase-dependent manner.

结论- ：在成人密度梯度分离BMMNCs，典型wnt3a促进stemness 增加及造血，而非典型信号通过wnt11强有力的诱导C-蛋白激酶和c-Jun-N -氨基末端激酶依靠性的心肌细胞分化。

We also demonstrate that BH3-only protein Noxa is upregulated during Camptothecin-induced apoptosis, which is independent of p53. In addition, we show that PI3k/Akt signaling pathway is responsible for Noxa\'s induction.

更重要的是，用RNAi的方法将Noxa的蛋白水平抑制之后可以显著地抑制CPT诱导的细胞凋亡，暗示Noxa在CPT诱导细胞凋亡的过程中起着非常重要的作用。

She gently rebuff ed him, but agreed that they could be friends

她婉言拒绝了，但同意作为朋友相处。

If in the penal farm, you were sure to be criticized.

要是在劳改农场，你等着挨绳子吧！