查询词典 sialic

Also,these results also show thatthe aberrant sialic acid on cancer evolutionary development is related to decrease ofthe gap-junction functions.

上述结果也说明了肿瘤由于唾液酸的增加促进肿瘤发生发展与细胞间隙连接功能降低有关。

Objectives and methods: The present study is undertaken to examine our hypothesis that with the accumulation of ion channels, increased sialic acids at the injury site or DRG somata result in a reduction of net transmembrane potential that evoke ESD in injured neurons.

膜蛋白的一个共同特性是其膜外域接受密集的糖基化，糖基含有大量带负电的唾液酸，如大部分离子通道，特别是电压依赖性的钠通道含有大量的唾液酸，而且这些负电荷靠近钠通道的电压感受器而易化通道开放。

Once inside the cell, ManNAc is processed into another sugar known as sialic acid that plays key roles in cancer biology, while butyrate orchestrates the expression of genes responsible for halting the uncontrolled growth of cancer cells.

一旦进入细胞，ManNAc被另外一种以知的在肿瘤的生物学行为中起重要作用的唾液酸处理，而在同时丁酸盐负责在停止肿瘤不受控制细胞生长的基因表达。

Objective To investigate the expression of sialic acid-binding immunoglobulin-like lectin-1 (Siglec-1) on peripheral blood lymphocytes, monocytes and neutrophils in patients with coronary heart disease and explore the role of Siglec-1 in coronary atherogenesis.

目的 观察唾液酸黏附素(Siglec-1)在冠心病患者外周血淋巴细胞、单核细胞和中性粒细胞上的表达水平，并探讨其在冠状动脉粥样硬化发病过程中的作用。

PART Ⅱ IMMUNOPATHOLOGICAL EVIDANCE OF SIALIC ACID STRUCTURE IN CAMPYLOBACTER JEJUNI AS THE CRITICAL ANTIGEN TO INDUCE PERIPHERAL NEUROPATHY To demonstrate the critical role of NANA structure in the pathogenesis of allergic peripheral neuropathy induced by Campylobacter jejuni and provide immunopathological evidence to confirm the supposition of molecular mimicry and cross-immunity between CJ LPS and gangliosides in nerve.

LPS免疫后第2周实验豚鼠的免疫血清中，抗LPS IgG抗体滴度均明显增高，第3周达高峰，第5周仍维持在峰水平，野生株和突变株LPS免疫血清中的抗-野生株LPS IgG抗体滴度较各自免疫前分别增高8倍和4倍，抗-突变株LPS IgG抗体滴度则较各自免疫前分别增高6.5倍和15倍；(2)全身免疫后第3周和第5周，野生株LPS免疫血清中检测到较免疫前增高6倍的抗-GM1 IgG抗体，而NANA缺失的突变株LPS免疫血清中一直未检测到抗-GM1 IgG抗体；(3)野生株LPS免疫组中有17.3％的坐骨神经原纤维发生以轴索变性为主（占65％）的免疫性损伤，与突变株LPS免疫组和对照组比较均有显著性差异。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。