查询词典 sialic

Methods:Fibrinogen was purified by precipitation from citrated plasma by saturated ammonium sulplvate.Fibrinogen-bound sialic acid levels with 22 controls and 113 liver patients were assayed by the thiobarbituric acid method.

应用饱和硫酸铵制备纯化纤维蛋白原，硫代巴比妥酸法测定22例正常人，133例肝病患者血浆FSA水平，并对血浆和纯化纤维蛋白原脱唾液酸化前后的凝血酶时间和纤维蛋白单体聚合浊度进行测定。

In this study, different nano-hydroxyapatite particles,HAP_1(25-60nm), HAP_4(the additives is heparin, 15-50nm), HAP_5(the additives is bovine serum albumin BSA, 20-80nm) were prepared by homogeneous precipitation and used heavy-gauge hydroxyapatite as comparison,we determined amount of heparin, sialic acid ,BSA adsorbed on HAP_1,HAP_2,HAP_3 by Crystal Violet assay, Bialsche method,Bradford method respectively and analyzed the binding mechanism by infrared spectrum;After taking HAP_1,HAP_2,HAP_4,HAP_5 and RBC to co-culture in vitro,we studied RBC hemolysis test and detected RBC hematolysis rate by erythrocyte osmotic fragility test;observing the changes of morphous and locomotion of cell after coacting HAP_1,HAP_2,HAP_4,HAP_5 and RBC by light microscope and inverted phase contrast microscope;observing HAP_1,HAP_2,HAP_4,HAP_5 effecting on Ultrastructure of RBC.

本文用均匀沉淀法制备了HAP_1(25-60nm)，HAP_4(添加剂肝素，15-50nm)，HAP_5(添加剂牛血清白蛋白BSA，20-80nm)等纳米粒子，并用大尺寸的羟基磷灰石HAP_2(470-520nm)，HAP_3(1906nm)作对照，分别利用结晶紫法、Bialsche法、Bradford法研究了肝素、唾液酸、血清白蛋白在HAP_1，HAP_2，HAP_3上的吸附量，用红外光谱分析其中的结合机理；在体外将HAP_1，HAP_2，HAP4_，HAP_5与红细胞共培养，进行了红细胞溶血试验的研究，并借助红细胞渗透脆性试验检测红细胞溶血率；运用普通光学显微镜和倒置相差显微镜观察了HAP_1，HAP_2，HAP_4，HAP_5与红细胞作用后细胞形态及运动的变化：透射电镜观察了HAP_1，HAP_2，HAP_4，HAP_5对红细胞超微结构的影响。

Based on our intensive studies on the lactonization of oligo/polysialic acids, we proposed for the first time that the lactone-ring formation of oligo/polysialic acids has three stages. We also provided a novel model to explain the conformational changes of oligo/polysialic acids caused by the repulsing forces among the carboxyl groups of sialic acid residues. Our results should provide novel approaches for further investigation of the structural-functional relationships of oligo/polysialic acids.

在对多/寡聚唾液酸内酯化过程进行深入研究的基础上，于国际上率先提出多/寡聚唾液酸内酯的形成具有三个阶段的观点，并首创性地提出了羧基排斥所致多/寡聚唾液酸分子空间构象改变的模型，为深入研究多/寡聚唾液酸结构与功能的关系提供了新生长点。

Objective:To explore the clinical significance of fibrinogen-bound sialic acid levels in patients with liver disease.

目的：探讨纤维蛋白原结合唾液酸在肝病患者中的意义及其对凝血酶时间的影响。

However, the nutritional and biological mechanisms of sialic acid in human body are still under investigation.

然而，营养和生物机制唾液酸对人体效果则仍在调查中。

In chapter 3, two on-line concentration CE methods for determination of sialic acid in saliva were developed.

在第三章，我们建立了两种在线富集毛细管电泳法测定人体唾液中的唾液酸。

To discuss the dynamic variation rule of sialic acid content in milk .

探讨牛奶中唾液酸含量的动态变化规律。

Objective To approach into the effect of serum sialic acidon the diagnosis and metastasis of malignant tumor.

目的探讨血清唾液酸对恶性肿瘤诊断价值及在肿瘤转移中的作用。

Objective To study the relationship between serum sialic acid and coronary atherosclerotic lesion.

近年来 ，冠心病的诊断和治疗已经有了长足的进步，但病因学研究进展缓慢。

Objective:To study relationship between serum sialic acid concertration and urinary albumin excretion ratein type 2 diabetic patients.

目的 研究 2型糖尿病尿白蛋白排泄率与血清唾液酸的关系。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。