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The team developed a siRNA product that specifically blocks the transcription of the gene that codes for IL-8, thereby blocking production of this protein, and encases it in a liposome delivery system. In mouse studies, this product showed activity against 2 ovarian cancer cell lines, both when used alone and when used in combination with docetaxel. In addition, the mouse studies revealed that the product was decreasing tumor growth through anti-angiogenic mechanisms — the treated tumors showed a lower microvessel density, the researchers report. This product was \"highly effective in our preclinical studies and may merit clinical development,\" they write. However, they also caution that the cell lines used to create the mouse models might not accurately reflect the heterogeneity seen in human tumors.

该团队发展一种siRNA產品，特别阻断IL-8的基因转译密码，因此阻断此一蛋白质之產生，且将它包入一个微脂粒传递系统；在老鼠研究中，不论单独使用或者和docetaxel併用，此產品显示对两种卵巢癌细胞线有活性；此外，老鼠研究发现此產品可透过抗血管新生机转减少肿瘤生长—报告指出，治疗的肿瘤显示较少的微血管密度，此產品在我们的临床前研究中相当有效，值得临床发展；不过，他们也表示，所用的老鼠研究中的细胞线可能无法精準反应人类肿瘤的异质性。

ResultsThe morbidities of the head,body and cauda of epididymides were 9.5%,14.3% and 76.2% respectively,80.2% of the foci showed low echo change.86.5% of the foci appeared the distribution of multivessels. RI of the epididymides showed cross phenomenon with that of normal epididymides.

结果附睾头、体和尾部发生率分别为9.5%、14.3%和76.2%；病灶内80.2%为低回声改变，86.5%呈多血管分布；RI与正常组有重叠现象。

Under the 6 h stress, SOD activity had been to maintain a high level, POD activity showed a greater change. When the stress lasted until 24 h, POD activity decreased and almost flatted compared with the control, this showed that POD activity was sensitive under the low temperature stress. Changes of CAT and SOD activity were in the line, the results indicated that activity of two enzymes coordinated the regulation of low-temperature adaptation.

本实验中，SOD活性一直保持较高的水平；POD活性表现为波动较大，当胁迫持续到24 h时，POD活性明显降低几乎与对照持平，说明POD受低温影响更敏感；CAT活性与SOD活性变化保持一致，表现出这两种酶在低温适应性调节过程中的协同作用。

The application results from fluorination showed microwave heating could accelerate chemical reactions markedly. The reaction time could be shortened 50% at least than that of conventional heating. The relationship between fluorinating agents\' structure and their activity was studied systematically. In addition, an anhydrous KF with higher activity was prepared by using expansion effect of microwave heating. As we known, solvents were very important to reaction. The comprehensive study showed some less polar aromatic solvents could be used as dipolar solvents. In addition, they had better effect than dipolar solvents in some occasions, such as fluorination of chlorobenzaldehydes and chlorinated diphenyl ketones etc. The primary applications of ionic liquids were also studied which indicated reactions with ionic liquids as solvents were more efficient and simple.

研究表明，微波是一种节能高效的加热方式，在微波作用下的卤素交换氟化反应具有反应速度快、转化率高、选择性好的优点，其反应时间可较常规加热缩短50%以上；同时也系统地研究了氟化剂种类及制备方式对其反应活性的影响，并利用微波加热的膨化作用制备出了一种活性较高的KF，其活性与喷雾干燥KF相差不大；溶剂对反应具有重要的作用，在此系统地研究了强极性非质子溶剂和中等极性非质子溶剂的应用情况，发现一些中等极性的非质子溶剂如硝基芳烃和氯代芳烃类溶剂在氯代苯甲醛类化合物的氟化反应中具有比强极性非质子溶剂更好的使用效果。

Additionally, one SsDRV-free strain Ep-1PNA183av that showed hypovirulence was isolated from a mutant of healthy strain Ep-1PNA183, this strain also immunizes the infection of SsDRV, it would be a valuable material to study on the interaction between SsDRV and its host. Surprisingly, we discovered that SsDRV could be transmitted into S. nivalis (in the same genus to S. sclerotiorum) when cultured side by side on PDA plate, this discovery may supply new evidence for the exchange of genetical elements among different species in fungi; the transmission of mycovirus to other species showed that the limitation of vegetative imcompatiblity among different strains might not be key factor to determine the efficiency of biological control with hypovirulence associated mycovirus.

发现了1株不携带SsDRV的核盘菌弱毒力菌株，该菌株对SsDRV具有显著抗性，是研究SsDRV与寄主互作的宝贵材料；还发现SsDRV可以在核盘菌种间传递，深入研究将为生物在种间的遗传物质交换提供了新的证据，也将为广泛利用弱毒相关病毒控制植物病害提供理论依据。

According to Griffing's method 1, diallel crossing was built and CA was analyzed. Variance analysis showed that there were the greatly significant difference among the both of GCA in inbreeds and SCA in crosses, respectively. The high GCA of 18-599 and 18-599 and the low SCA variance of their crosses showed the strong and stable heredity on the both characters. Taking them as parents, the generations with high and stable induction and regeneration will be gotten.

2选用在配合力、抗病性、农艺性状等玉米杂交育种性状与幼胚培养胚性愈伤组织诱导率和胚性愈伤组织绿苗发生数等转基因工程育种性状都表现相对十分优异的18-599、18-599和综31等3个自交系，以及杂交育种性状表现优良、但转基因工程育种性状表现极差的A318，P138和R15等3个自交系为亲本，按照Griffing方法1组配双列杂交，进行Griffing的配合力分析。

Author was menstruated content of boron and researched the status of lack of Boron and researched relativity of its Influencing facto, the results showed that the average content of available boron in the yellow soil was 0.39±0.27 mg/kg, 80 percent of its was under 0.5mg/kg which was lack for boron and 17.44 percent of its was under 0.2mg/kg which was especially lack for boron; The distribute frequencies of available boron contents of yellow soils in Chongqing was dispersedly, its range of 0.07mg/kg to 1.99mg/kg. The diversity of different zoology area was distinct. The result of pertinence analyses showed that available boron contents had correlativity with the pH(r=0.181** n=281) and CEC（r=0.124** n=281 and It had correlativity with Organic matte When the content of organic matte is high; in addition, soil granule、clime was the Influencing factor of availability of boron in Yellow Soils in Chongqing.

笔者通过调查取样对重庆市黄壤硼的含量进行测定并分析了缺硼的程度，对其影响因素进行了相关性分析，研究结果表明：重庆市黄壤有效硼的平均含量为0.39±0.27mg/kg，其中近80%的土壤样品有效硼含量低于0.5mg/kg，属于低硼或缺硼土壤，还有17.44%的土壤样品有效硼含量低于0.2mg/kg，属于极度缺硼的土壤；而有效硼含量的分布频率比较分散，变幅较大，从0.07mg/kg~1.99mg/kg，变异系数达到69.41%，不同生态类型区土壤有效硼含量的差异十分明显；而相关性分析结果表明：土壤有效硼与土壤pH值(r=0.181** n=281)和CEC（r=0.124** n=281呈正相关，在有机质含量较高的条件下与其相关性也较为显著（r=0.347** n=90，而土壤质地以及气候也对重庆市黄壤硼的有效性有很大的影响

The seeds of Adzuki bean were irradiated by 60 Co γ ray of 0～700Gy.The results showed that:(1)The sub\|lethal dose(LD 50 )was 389Gy and the early seedling leaf at M\-1 showed incised,chlorotic,yellow,mosaicand curly edge.The absorbed dose was related with the rate of misshaped leaf.Chromosomal aberration, chromosome bridge and fragment of M\-1 in the tip were observed.If the seed was irradiated with 400Gy,the rate of abnormal cell at the root was more than 10%.The relationship between pollen fertility and irradiation dose was negative correlated.

本试验研究结果表明：60 Coγ射线辐照小豆种子的半致死剂量平均为 3 89Gy ，且M1生长初期叶片性状有明显的叶面缺刻、叶色缺绿、叶形不对称、叶缘卷曲、花叶、黄叶等致变现象，各种畸型叶出现频率与辐照剂量大小有关；M1根尖细胞中有多种染色体畸变类型，以染色体桥和断片频率较高，辐照剂量在 40 0Gy以上时根尖细胞异常率达 1 0 %以上；植株花粉育性与辐照剂量呈极显著负相关，京农 2号植株花粉育性达 5 0 %时的辐照剂量为 3 78Gy。

In transvaginal,CDFI showed 81 5% and CDE showed 90 7% of blood signals inside or around the myomas.

7%的 CDE有血流信号。结论：经阴道途径较经腹壁途径灵敏度更高。

The results showed that immunopositive substance existed in the ovary and testis of different stages. At the early developmental stage of ovary, the cytoplasm and nucleolar membrane of oogonia and early primary oocyte showed immunopositive reaction with strong or medium intensity to 17 b -estradiol, testosterone and progesterone antibodies.

在卵巢发育早期，卵原细胞和卵母细胞的胞质和核仁膜对雌二醇、睾酮和孕酮抗体显示强或中等强度免疫阳性反应；在大生长期和成熟期，卵母细胞胞质和核仁膜对睾酮和孕酮抗体的免疫阳性反应明显减弱，而对雌二醇则显著增强。

Singer Leona Lewis and former Led Zeppelin guitarist Jimmy Page emerged as the bus transformed into a grass-covered carnival float, and the pair combined for a rendition of "Whole Lotta Love".

歌手leona刘易斯和前率领的飞艇的吉他手吉米页出现巴士转化为基层所涵盖的嘉年华花车，和一双合并为一移交&整个lotta爱&。

This is Kate, and that's Erin.

这是凯特，那个是爱朗。