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Day puppies were inoculated by abdominal cavity and nasal cavity with CDV,canine distemper patho-sample of duplicating meet with success and through differentdrug of treatment, specific antibody, dexamethasone, causing death by letting. Theresults of pathohistology observation on 14 PID: Control group, the hearts showedcardiac muscle hemorrhage and necrosis, the livers showed a large area of hepatictissue hyperemia, hemorrhage and necrosis, the spleens showed the quantity oflymphocyte grow downwards, the blood vessels of lung congested, congestion andhaemorrhage were serous fluid exudation, the kidneys showed heavy haemorrhageand hyperemia, the cerebrum showed the number of microglial cells of cerebrumincreased.

通过特异性抗体和地塞米松、特异性抗体、地塞米松三种不同的方法治疗后，放血致死，取材作病理切片，观察各组病理组织学变化，结果为：感染后14d阳性对照组的心脏表现为心肌出血、坏死；肝脏表现为肝组织大面积充血、出血坏死；脾脏表现淋巴细胞数量大量减少；肺脏表现为肺泡结构破坏，有坏死灶；肾脏表现为弥漫性的充血出血；大脑表现为胶质细胞增多。

Most (14 out of 17, 82%) duodenal biopsies showed apoptotic counts of ≥2/100 crypts, 28%(5 out of 18) of gastric biopsies showed apoptotic counts of ≥3/100 glands, and 57%(4 out of 7) of esophageal biopsies showed apoptotic counts of ≥2/10 high-power field. Four gastric biopsies showed a previously undescribed injury pattern of parietal cells resembling the ballooning degeneration.

大多数十二指肠活检（17例中有14例，82%）的细胞凋亡计数为≥2个/100个隐窝，28%胃活检（18例中有5例）的凋亡计数为≥3个/100个腺体，57%食管活检（7例中有4例）的凋亡计数为≥2个/10个高倍视野。4例胃活检的壁细胞出现了一种以往不曾认识的损失模式——酷似气球样变性。

The rules of photo bioactivities are: Without illumination, the tested xanthene derivatives showed almost the same level of inherent toxicity to the same organism, which showed the inherent toxicity of xanthene derivatives were primarily dependent on the structure of parent molecule. Upon illumination, the photosensitizers showed obvious phototoxicity to all organisms. The xanthene derivatives showed stronger phototoxicity to Gram-positive bacteria. With the increasing number of halogen substituents, the singlet oxygen yields increased and the phototoxic activity increased too.

呫吨类化合物的生物活性的变化规律为：未经光照的条件下，呫吨类化合物的对同种待测微生物的固有生物活性基本相同，说明固有毒性可能主要决定于化合物分子的母核结构，其卤素取代基团对其影响较小；经实验光源照射下，所测MLC值明显低于未经光照条件下的值，表明呫吨类化合物对三种微生物的光敏活性明显强于对其相应的固有活性；呫吨类化合物对革兰氏阳性菌能发挥较大的光敏活性。

Toxicity and repellent activity of several plant-based compounds on Blattella germanica were studied, results showed that rotenone, toosendanin and azadirachtin had stomach toxic effect on Blattella germanica, rotenone showed high stomach toxicity and all insects died after 8 hours, matrine also has deformative effect on Blattella germanica , matrine and toosendanin can affect oviposition of Blattella germanica; repellent activity of these botanicals was further studied, results showed that bering hydrochloridum, azadirachtin and sparteinehave had repellent activity against Blattella germanica, observation also showed that rotenone and bering hydrochloridum had high contact toxicity against Blattella germanica, the time of all insects knocked down were 8 and 48 hours.

选取了7种植物源化合物，测定了它们对德国小蠊的毒性和驱避性，结果表明，鱼藤酮、川楝素和印楝素对德国小蠊具有不同程度的胃毒作用，其中鱼藤酮乙酸乙酯溶液作用较强，8小时死亡率已达100％，川楝素和印楝素对德国小蠊也表现出一定的毒杀作用，观察还发现印楝素和苦参碱对德国小蠊的发育有致畸作用，苦参碱和川楝素影响其卵鞘形成；进一步对这几种化合物的驱避性进行研究，结果表明盐酸黄连素、鱼藤酮乳油和印楝素乳油对德国小蠊有不同程度的驱避作用，其驱避率分别为96.7％、51.3％和50.1％，另外观察到鱼藤酮乙酸乙酯溶液和盐酸黄连素对德国小蠊具有较强的触杀活性，供试虫全部被击倒的时间分别为8小时和48小时。

Results The whole genome of CVB4 jlu06 strain consisted of 7 395 nucleotides encoding 2183 amino acids, which showed high homologies to other CVB4 strains, with the mutations of 10 amino acids. Phylogenetic analysis proved that CVB4 jlu06 strain showed close relationship to HumanCB4 and POLG_CXB4 strains while showed remote relationship to CXB2 strain. Unlike other non-diabetogenic strains, CVB4 jlu06 strain showed common amino acids with diabetogenic strains at 4 sites in 3A region of non-structural protein.

结果 CVB4 jlu06株基因组全长7395个核苷酸，编码2183个氨基酸，与其他CVB4株的同源性较高，且发生了10个氨基酸的变异，与HumanCB4和POLG_CXB4亲缘关系较近，与CXB2亲缘关系较远；CVB4 jlu06株与具有潜在致糖尿病性病毒株，在非结构蛋白3A区4个位点有共同的氨基酸，与非致病毒株不同。

The synthesized PCU was then characterized by infrared spectroscopy, differential scanning calorimetry, thermogravimetric analysis, small-angle X-ray scattering, and tensile strength measurement. The IR showed that the polymer synthesized by the above two methods both have the polycarbonate-urethane structure and the tensile measurement showed good mechanical performance of the polymer. The DSC and TGA data showed that there is an obvious soft-hard glass transition area, which indicated the existence of the micro-phase separation structure. The extent of the phase separation was affected by the ratio of starting materials, the molecular weight of PCD, and the polymerization method. The decomposition upon heating was observed in two steps. SAXS result showed that the radius (r_2), the distance between domains (d_2), and gyral radius (R_2) of hard segment micro-domain were fairly affected by the starting materials ratio and soft segment content.

IR结果表明两种方法合成的聚合产物均具有聚碳酸酯聚氨酯的结构；拉伸实验表明聚合产物具有良好的力学性能；DSC、TG结果表明，聚合物呈现出较为明显的软硬段玻璃化转变区，表明存在微相分离的结构，相分离的程度受原料配比、软段分子量、聚合方法的影响，其热分解分为明显的两个阶段； SAXS结果表明，聚合物原料配比、软段含量的变化对硬段微区回旋半径R_2，微区间距d_2，微区半径r_2影响不大其值分别为9.5(A|°、29、7.4，但对软段的微区半径及间距影响较大，随着软段含量的增大，软段微区的半径r1和间距d1都增大。

Results showed that rapid cycling patients were more likely to be female, a fact more evident in bipolar I than bipolar II patients. Rapid cycling patients also showed a younger age of onset and a higher occurrence of depression at study entry. In the year prior to the study, the rapid cycling group showed poorer global functioning and a significantly greater rate of depressive and hypomanic/manic episodes. History of psychosis showed no correlation with rapid cycling but bipolar I patients were more likely to have symptoms of psychosis than bipolar II patients.

研究结果显示，快速循环病患以女性较多，而在两极I及两极II病患中更明显，快速循环病患发病年龄较轻，在研究期间较常出现忧郁症状，研究之前一年，快速循环组显示较低的整体功能，且有明显较高比例的忧郁及轻躁症/狂躁症，但是精神病史显示这与快速循环没有关系，但两极I比两极II病患更容易出现精神病症状。

By non-enhancement scan, 12 cases showed low density mass, 4 cases equal density mass, 1 case slightly high density mass, and 2 cases stippled calcification mass. By enhancement scan, 13 cases showed inhomogenous enhancement in cortical phase, 2 cases showed slight to moderate enhancement. Another 2 cases of small cystic RCC presented enhancement of wall with nodules and the partition. The enhancement of all tumor cases faded away in the following parenchymal phase and pyelographic phase, demonstrating some degrees of "fast washing out" phenomenon; 4 cases presented with pseudocapsule. The reconstruction of 17 "MPR/MIP" and 9 "VR" showed clearly the relations of kidney vessels, tumors and neighbor tissues and accessory renal arteries were founded in 2 cases.

结果：17例中小实性肾癌15例，小囊性肾癌2例；CT平扫呈低密度12例，等密度4例，稍高密度1例，伴有斑点状钙化2例；增强扫描皮质期13例呈不均匀明显强化，2例呈轻中度强化，另2例小囊性肾癌的囊壁、壁结节及囊内分隔明显强化；实质期、肾盂期扫描所有肿瘤强化均迅速减退，呈&快进快退&改变；4例可见假包膜。17例MPR/MIP、9例VR重建均能清楚显示肾血管、肿瘤与邻近组织的关系，并发现副肾动脉2例。

Results In 11 cases,5 cases were intracranial,and 6 cases intravertebral canal.MRI could effectively show similarly shuttle or long-round shape's abnormal signal imaging.The T1W imaging showed uniformity or asymmetric and low or equal signal.The borders were slighty low or equal signal intensity,some had spetum.The T2W imaging showed obviously high signal,and a few cases showed slightly high or equal signal,while the borders showed slightly low or equal signal imaging.The thin peripheral could be obviously enhanced,but without inner enhancement.

结果 11例中发生于颅内5例，椎管内6例，其 MRI 表现：断面上显示为在颅板下或椎管内的梭形或长圆形异常信号影， T1WI 上表现为均匀或不均匀的低、略低或等信号影，周边为略低或等信号的较厚边缘，少部分（2例）有分隔； T2WI 上多表现为较明显的高信号，少数呈等、略高信号，并可见略低或等信号的边缘；增强扫描病灶边缘明显强化，其内无明显强化或不强化，1例病灶呈较均匀的强化，1例病灶部分呈片状强化。

The results of bioassay indicated: 1 The new compound (compound 6) and other three compounds (compound 1, 2 and 5) showed strong anti-HIV activity (EC50.064μg/ml), compound 3 and 4 showed less activity (EC50=6.18μg/ml and 12.85μg/ml respectively); Compound 5 and 6 showed weak cytotoxicity, and compound 1-4 showed moderate cytotoxicity; 2 Compound 5 and 6 were activated to all the four tested microbial; Compound 1, 2 and 13 were activated to all the three tested bacterial, but were unactivated to the tested fungi, Penicillium avellaneumUC-4376; One of the test bacterial, Staphylococcus aurues, seemed to be sensitive to all the eleven triterpenoids.

新化合物（化合物6）和化合物1、2、5具有强烈的体外抗HIV活性，其EC50值均小于0.064μg/ml，化合物3和4也具有抗HIV活性，但活性相对较弱，EC50值分别为6.18μg/ml和12.85μg/ml；化合物1-6都具有一定的细胞毒性，且化合物5和6的细胞毒性明显弱于化合物1-4的。 2）新化合物（化合物6）和化合物5对所有四种试验菌都有一定的活性；化合物1 、2和13对三种细菌均有一定的活性，但对真菌橙色青霉UC-4367（Penicillium avellaneum UC-4376）无活性；金黄色葡萄球菌对所有11个三萜都较为敏感。

According to the clear water experiment, aeration performance of the new equipment is good with high total oxygen transfer coefficient and oxygen utilization ratio.

曝气设备的动力效率在叶轮转速为120rpm～150rpm时取得最大值，此时氧利用率和充氧能力也具有较高值。

The environmental stability of that world - including its crushing pressures and icy darkness - means that some of its most famous inhabitants have survived for eons as evolutionary throwbacks, their bodies undergoing little change.

稳定的海底环境─包括能把人压扁的压力和冰冷的黑暗─意谓海底某些最知名的栖居生物已以演化返祖的样态活了万世，形体几无变化。