查询词典 severe

objective trimetazidine has shown anti-ischemic properties to improve exercise tolerance without haemodynamic effects and direct cyto protective effect on the myocardium.however,it is not clear whether trimetazidine has beneficially effect on severe ischemic cardiomyopathy.methods 19patients（68±9）years with postnecrotic left ventricular dysfunction（ejection fraction31.7%±5.4%）were studied to examine the benefit of adding60mg a day of trimetazidine for3months to the classical therapy.the assessment included clinical evaluation,electrocardiography and echocardiography.results after adding60mg a day of trimetazidine for3months,attack of angina was relieved and dyspnea was improved（p.05）.but heart rate,systolic blood pressure,rate pressure product,ejection fraction,left ventricular volume and global wall motion index were not changed.conclusion trimetazidine seems to improve clinical status while can not change oxygen supply-to-demand ratio without adverse effects in patients on severe ischemic carˉdiomyopathy.

目的 曲美他嗪是一种新型的抗心肌缺血的药物，能够改善患者的运动耐量和心肌的直接保护作用同时并没有血流动力学效应。但目前对于严重缺血性心肌病患者的临床治疗价值还需要进一步观察。方法 19例（68±9）岁确诊为缺血性心肌病（左心室射血分数0%）的患者在常规治疗的基础上加用每日60mg曲美他嗪治疗3个月，随诊观察患者临床情况以及超声心动图指标的变化。结果 19例患者均可耐受在常规治疗基础上加用每日60mg曲美他嗪的治疗，随诊发现患者心绞痛发作明显减少，运动耐量明显改善。同时患者心率、收缩压、心率血压乘积、左心室射血分数、左心室容量以及整体室壁运动指数无明显改变。结论缺血性心肌病的患者在常规治疗基础上加用曲美他嗪是安全的，同时其能明显改善患者的临床状态，而这种作用并不改变心肌氧的供求比值。

Severe secondary bleeding may occur after nasal endoscopic surgery due to sphenopalatine artery injury, bleeding often occurs about one week postoperatively. Endoscopic electric coagulation hemostasis as well as intranasal packing with is an effective method for treatment of severe secondary bleeding after nasal endoscopic surgery.

鼻内镜手术后可因蝶腭动脉损伤出现术后继发严重性出血，出血时间常发生在术后1周，鼻内镜下电凝止血加碘仿纱条填塞压迫是一种有效的治疗方法。

From moderate to severe high blood pressure will be large fluctuations in blood pressure, causing palpitation, palpitations or thoracodorsal pain, the situation can be induced by severe angina, myocardial infarction and other cardiovascular and cerebrovascular accidents.

中重度高血压者的血压则会大幅波动，引起心慌、心悸或胸背痛，情况严重时还可诱发心绞痛、心肌梗塞等心脑血管意外。

Meta-analysis based on included studies showed that response rate of TP regimen has no statistic significance compared with EP regimen[OR0.83,95%CI(0.63-1.090)],but myelo-suppression such as leucopenia and thrombopenia is more severe; response rate of single topotecan has no statistic significance compared with CE regimen[OR0.59,95%CI(0.22-1.60)]; response rate of TEP regimen has no statistic significance compared with EP regimen [OR1.37, 95%CI(0.82-2.28)], but myelo-suppression such as leucopenia, thrombopenia and anemia is more severe; response rate of IV topotecan has no statistic significance compared with Oral topotecan[OR0.97, 95%CI(0.60-1.57)],so as median time to progression[WMD-2.32, 95%CI(-5.72,1.09)] and median survival time[WMD-1.65, 95%CI(-7.13,3.83)],while neutropenia is more sever in IV topotecan than Oral topotecan.

分析表明，TP方案与EP方案的反应率相似[OR0.83，95％CI(0.63-1.090)]，但具有相对高的致白细胞和血小板下降的骨髓毒性；单药拓扑替康与CE方案的反应率相似[OR0.59，95％CI(0.22-1.60)]；TEP方案与EP方案的反应率相似[OR1.37，95％CI(0.82-2.28)]，TEP方案致化疗后重度白细胞下降、重度血小板下降、重度血红蛋白下降均高于EP方案；口服拓扑替康与静脉滴注拓扑替康的化疗后反应率[OR0.97，95％CI(0.60-1.57)]、中位疾病进展期[WMD-2.32，95％CI(-5.72，1.09)]、中位生存期[WMD-1.65，95％CI(-7.13，3.83)]相似，口服拓扑替康化疗后重度中性粒细胞下降明显低于静脉滴注拓扑替康。

Plasma exchange therapy can recover the liver function and improve the thromboplastic mechanism, and decrease the abnormal immunological reaction of patients with severe viral hepatitis, and maintain stabilization of inner environment. The PE therapy is safe and effective for severe viral hepatitis.

血浆置换治疗可以改善重型肝炎患者的肝功能和凝血功能状态，减轻异常免疫反应，维持内环境稳定。

To study the etiology and treatment of relapsing polychondritis, especially tracheostenosis, 3 patients with severe relapsing polychondritis complicated with severe tracheostenosis were presented.

为提高对复发性多软骨炎尤其是合并气管严重狭窄的重症病例的认识，探讨复发性多软骨炎气管狭窄的病因和治疗方法，总结分析了 2 0例复发性多软骨炎中合并气管严重狭窄的重症复发性多软骨炎 3例。

Results Serum EDLS increased within 24 h after brain trauma of different degree in all patients with brain injuries of various intensities.The group of slight injury was the most typal,EDLS demonstrated no change or decrease in a few patients with the injury intensity growing;In most cases EDLS decreased after brain operation or accompaning the wounded recovery; Contents of EDLS at 24 h among different pathological types of brain injuries showed no difference, but in the successful recovery patients with severe or ultra-severe brain injuries, EDLS contents at 72 h posttrauma were lower than in the patients of death or disability. The above change characteristics of EDLS related to injury locations and the degree of brain injury.

结果 不同程度脑外伤后24小时内血清EDLS均升高，以轻伤组最为典型；随着损伤程度的加剧，少数病例EDLS不变甚至下降；术后或随伤情的恢复，EDLS多同步下降；不同病理类型的脑损伤24小时内EDLS无明显差异，在成功康复的重型、特重型脑损伤病人，伤后72小时EDLS含量低于死亡或伤残组；EDLS 的上述变化特点与损伤部位和程度不同有关。

Results Of them, 35 cases were diagnosed mild acute unobstructive biliary pancreatitis, 22 cases mild acute obstructive biliary pancreatitis, 20 cases severe acute unobstructive biliary pancreatitis and 27 cases severe acute obstructive biliary pancreatitis.

2004年6月至2006年12月间收治胆源性急性胰腺炎104例，根据有无胆道梗阻及轻重程度分为4类：轻症非梗阻型、轻症梗阻型、重症非梗阻型、重症梗阻型，对其临床治疗结果进行回顾性分析和总结。

"The country is probably going through the most severe credit crunch since 1991-92," Wyss said, referring to a time when banks and savings and loans came under severe pressure while the economy was in a recession.

Wyss根据经济在衰退时期银行、贷款、存款受到巨大的压力时说，整个国家将遭受自1991-92年来最严重的信贷危机，他认为银行的信贷在一段时间内会保持从紧的政策。

NOD/SCID (non-obese diabetic/severe combined immunodeficient) mice are immunodeficient mice which are generated by backcrossing severe combined immunodeficient mice with non-obese diabetic mice strains.

NOD/SCID（非肥胖糖尿病／重症联合免疫缺陷）小鼠是在SCID小鼠的基础上与非肥胖性糖尿病小鼠品系回交的免疫缺陷鼠。

Breath, muscle contraction of the buttocks; arch body, as far as possible to hold his head, right leg straight towards the ceiling (peg-leg knee in order to avoid muscle tension).

呼气，收缩臀部肌肉；拱起身体，尽量抬起头来，右腿伸直朝向天花板（膝微屈，以避免肌肉紧张）。

The cost of moving grain food products was unchanged from May, but year over year are up 8%.

粮食产品的运输费用与5月份相比没有变化，但却比去年同期高8％。