查询词典 sever

Conclutions Topotecan is an effective remedy for treatment of small cell lung cancer, both single topotecan and combined regimen has the same effect as the traditional first-line regimen, though myelo-suppression such as leucopenia and thrombopenia is more sever, the adverse effect is tolerated. Though it has been recommended as second-line agent for chemo-therapy sensitive small cell lung cancer, there needs more clinical studies to verify its role in first-line.

结论拓扑替康是在小细胞肺癌的治疗中有确切临床疗效的药物，无论是单药还是与其他药物的联合用药均具有与当前一线经典方案相当的疗效，虽具有相对高的致白细胞和血小板下降的骨髓毒性，但毒副作用可耐受，已经被认为是治疗对化疗敏感的小细胞肺癌患者的二线推荐药物，但是作为一线用药仍然需要更多的临床证据来证实。

Meta-analysis based on included studies showed that response rate of TP regimen has no statistic significance compared with EP regimen[OR0.83,95%CI(0.63-1.090)],but myelo-suppression such as leucopenia and thrombopenia is more severe; response rate of single topotecan has no statistic significance compared with CE regimen[OR0.59,95%CI(0.22-1.60)]; response rate of TEP regimen has no statistic significance compared with EP regimen [OR1.37, 95%CI(0.82-2.28)], but myelo-suppression such as leucopenia, thrombopenia and anemia is more severe; response rate of IV topotecan has no statistic significance compared with Oral topotecan[OR0.97, 95%CI(0.60-1.57)],so as median time to progression[WMD-2.32, 95%CI(-5.72,1.09)] and median survival time[WMD-1.65, 95%CI(-7.13,3.83)],while neutropenia is more sever in IV topotecan than Oral topotecan.

分析表明，TP方案与EP方案的反应率相似[OR0.83，95％CI(0.63-1.090)]，但具有相对高的致白细胞和血小板下降的骨髓毒性；单药拓扑替康与CE方案的反应率相似[OR0.59，95％CI(0.22-1.60)]；TEP方案与EP方案的反应率相似[OR1.37，95％CI(0.82-2.28)]，TEP方案致化疗后重度白细胞下降、重度血小板下降、重度血红蛋白下降均高于EP方案；口服拓扑替康与静脉滴注拓扑替康的化疗后反应率[OR0.97，95％CI(0.60-1.57)]、中位疾病进展期[WMD-2.32，95％CI(-5.72，1.09)]、中位生存期[WMD-1.65，95％CI(-7.13，3.83)]相似，口服拓扑替康化疗后重度中性粒细胞下降明显低于静脉滴注拓扑替康。

As the turbomachine is designed to operate at higher speeds, the stability of the rotor system becomes more sever.

透平机械转子动力系统的运动稳定性问题是目前转子动力学中的一个热点课题。

Vorpal: This potent and feared ability allows the weapon to sever the heads of those it strikes.

斩首：这种强大而可怕的能力使得武器能砍下敌人的头颅。

After a vicious campaign which lasted sever long years, the Scorpion King and his army were defeated, and driven deep into the sacred desert of Ahm Shere.

经过长达7年的战役，魔蝎大帝的军队大败，一路溃退至神圣的沙漠，阿姆谢。

Sever the Reed decoration: As Zhan Nifu best friend, her ruthless not under heart warning; But she weak, appeases, will only cause more and more innocent men to die in Zhan Nifu in the hand.

手足无措：作为詹妮弗最好的朋友，狠不下心报警；可是软弱、姑息，只会导致越来越多的无辜男子死在詹妮弗手上。

No man can sever the bonds that unite him to his society simply by averting his eyes .

没有人可以因为他自己视线的转移而轻易切断他与社会的关联。

No man can sever the bonds that unite him to his society simply by averting his eyes.

没有人能够仅凭闭目不看社会的现实，就割断自己同社会的联系。

No man can sever the bonds that unite him to his society simply by averting his eyes .

没有人可以试图闭上眼睛去割断与外界的联系。

No man can sever the bonds that unite him to his society simply by averting his eyes .

没有人能够切断他跟这个社会的联系，仅仅通过简单地改变他的眼见。

Lugalbanda was a god and shepherd king of Uruk where he was worshipped for over a thousand years.

Lugalbanda 是神和被崇拜了一千年多 Uruk古埃及喜克索王朝国王。

I am coming just now,' and went on perfuming himself with Hunut, then he came and sat.

我来只是现在，'歼灭战perfuming自己与胡努特，那麼，他来到和SAT 。