查询词典 serine

Algin, Atelocollagen, Serine film can form a layer of moisture, increasing skin moisture degrees, to maintain long-lasting skin moisturizing effect, improving the skin is not easy on the makeup Fufen phenomenon.

Algin， Atelocollagen， Serine能形成一层保湿膜，增加肌肤含水度，维持皮肤长效保湿效果，改善肌肤不易上妆、浮粉的现象。

Several coterminous bands could be observed by PAGE of natural Eisenin Ⅰ and several coterminous peaks of Eisenin Ⅰ were also detected with MALDI-TOF-MS when the molecular weight of three main peaks are 24, 645, 25, 052 and 25, 281, separately. The amino acid composition of Eisenin Ⅰ(pI. 8) is specilized with high content of acidic amino acids and low content of alkaline amino acids; At the same time, the content of Ser and Thr are quite high and that of Lys, Met, Phe and Trp are quite low. Eisenin Ⅰ is highly homologous with serine proteases. Then, by fibrin plate assay, Eisenin Ⅰ was identified to be a plasmin and also a plasminogen activator, and the fibrinolytic activity was inhibited by PMSF (an inhibitor of serine proteases).

赤子素Ⅰ氨基酸组成特点为高的酸性氨基酸和低的碱性氨基酸含量，且Ser、Thr含量高而Lys、Met、Phe和Trp含量很低；等电聚焦电泳测得其等电点pI.8.N端序列比较结果显示赤子素Ⅰ与丝氨酸蛋白酶类高度同源，纤维蛋白平板法测得赤子素Ⅰ同时具有纤溶酶和纤溶酶激酶活性；通过PMSF对赤子素Ⅰ纤溶酶活性的抑制实验证明，赤子素Ⅰ属于丝氨酸蛋白酶类。

Rice bran wax to fatty acids and senior wax mainly composed of alcohol, fatty acids are palmitic acid (C16), Gan II acid (C22), wood wax acid (C24), wax acid [26 acid] (C26) and other major components of wax alcohols have wax alcohol (C26), different serine alcohol wax, beeswax alcohol (C30), etc.; also contains alcohol to beeswax (C30), wax alcohol, alcohol wax for different serine The main constituents of unsaponifiable matter and a number of free acid mainly palmitic acid is brown, trace of alcohols, 30, such as carbon six elemene liposome.

米糠蜡以脂肪酸和高级蜡醇为主要成分，脂肪酸中有棕榈酸（C16）、甘二烷酸（C22）、木蜡酸（C24）、蜡酸（C26）等主要蜡醇成分中有蜡醇（C26）、异丝氨酸蜡醇、蜂蜡醇（C30）等；另外还含有以蜂蜡醇（C30）、蜡醇、异丝氨酸蜡醇为主要成分的不皂化物及若干游离酸（主要是棕是棕榈酸、微量醇类、三十碳六烯脂质等。

Gene sequence was highly homologic with a gene encoding aβ- subunit of ATP synthetase and an EST originating from a cDNA in relation to water deficit stress, which both were closely associated with the protein functioning in stress resistance and ion transportation. The results suggested that No. 1 gene sequence was involved in stress resistance of apple rootstock. No. 2 gene sequence had high homology with a gene encoding a serine/ threonine kinase protein, indicating perhaps it was a new gene encoding the serine/ threonine kinase protein in apple rootstock. The gene sequences of A1 and A2 were highly homologic with a gene encoding aβsubunit of ATP synthetase.

对得到的差异片断进行回收、测序，通过BLAST和其它植物比对，发现Ⅰ号序列与一条编码ATP合酶β亚基基因和一条水分亏缺胁迫cDNA克隆基因EST的同源性非常高，该序列编码涉及到了抗性表达、离子转运基因，可能参与了植物抗性表达，说明获得的基因序列应是与苹果砧木抗性相关的基因；Ⅱ序列与一条serine/threonine kinase蛋白激酶的蛋白序列同源性比较高，核酸比对较低，可能是具有丝氨酸/苏氨酸蛋白激酶功能的新基因。A1、A2序列与一条编码ATP合酶β亚基基因的同源性较高。

Cycloserine was produced using L-serine methyl ester hydrochloride as raw material. L-serine methyl ester hydrochloride was chloridized with phosphorus pentachloride to afford 2-amino-3-chloride propanic acid methyl ester hydrochloride, which was cyclized with hydroxylamine in the presence of alkali to give cycloserine.

以L-丝氨酸甲酯盐酸盐为原料制备了环丝氨酸。L-丝氨酸甲酯盐酸盐和五氯化磷在氯仿溶剂中进行氯代反应生成2-氨基-3-氯丙氨酸甲酯盐酸盐，后者和羟胺在碱性溶液中发生环合反应得到环丝氨酸。

The patients with lower serum glycine or D-serine levels, more severe negative symptoms and cognitive deficits, abnormal expression in mRNA or protein levels of certain genes (e.g., lower expressions of SHMT2, PSAT1 and serine racemase; higher expressions of AMT and ASCT1) may be more likely to respond to sarcosine.

此外，用药前具有较低的血清glycine或D-serine浓度、较明显的负性症状或认知功能缺损、以及特定基因於mRNA或蛋白质层次表现异常(如：SHMT2、PSAT1及serine racemase表现较低，而AMT及ASCT1表现较高)的患者，可能对sarcosine有较佳的治疗反应。

To date, there have been a few clinical trials exploring the efficacy of NMDA enhancers as adjuvant therapy. For instance, D-serine (an endogenous agonist of the NMDA-glycine site) and sarcosine (N-methylglycine, an endogenous glycine transporter I inhibitor) are not only well-tolerated but also synergistic in improving positive, negative symptoms and cognitive function in chronic patients receiving typical or atypical antipsychotics. We just completed the first trial applying NMDA enhancers in acutely exacerbated schizophrenia patients with collaboration with Harvard University, and the results showed that sarcosine was superior to D-serine in efficacy.

目前已有将NMDA促进剂作为辅助用药的临床研究，例如，D-serine (一种内生性NMDA-glycine site致效剂)、sarcosine (即N-methylglycine，一种内生性glycine transporter I 抑制剂)等，结果显示它们不但安全，且能加强传统及新一代抗精神病剂对慢性患者活性、负性症状及认知功能的疗效；我们日前与哈佛大学合作完成目前唯一将NMDA促进剂用於急性患者的研究，结果发现，sarcosine的疗效又优於D-serine。

Ve schizophrenic inpatients will be enrolled into the 6-week, randomized, double-blind trial of sarcosine monotherapy (1000~3000 mg/day, N=75) vs. risperidone (2~6 mg/d, N=75). We will measure clinical efficacy and side effects biweekly during the treatment. At the beginning and the end of the trial, we will also measure cognitive function (e.g. intellect, attention, memory, executive function), serum amino acids, expressions of mRNA (by realtime quantitative RT-PCR) and protein of NMDA-related genes (such as SHMT2, AMT, PSAT1, ASCT1, and serine racemase) in peripheral blood lymphocytes.

第一部份将收案150位未曾治疗之精神分裂症住院患者，以双盲方式随机给予六周sarcosine (1000-3000 mg/day，N=75)或risperidone (2-6 mg/day，N=75)治疗，我们将每两周评估临床疗效与安全性，并在研究开始及结束时，评量认知功能(智能、注意力、记忆力、执行功能)并测定血清中glycine或D-serine浓度以及SHMT2、AMT、PSAT1、ASCT1、serine racemase等基因於周边淋巴球之mRNA (以realtime RT-PCR测定)与蛋白质表现量。

All C.neoformans contain serine protease; Serine proteinase perturbs the integrity of BMEC of the blood-brain barrier, improves open the level of BBB; Secreted serine protease from pathogenic fungi were virulence.

发现新生隐球菌分泌具有活性的胞外蛋白水解酶并含有丝氨酸蛋白酶成分；新生隐球菌自身分泌的丝氨酸蛋白酶可以干扰构成血脑屏障主要成分内皮细胞的完整性使得血脑屏障开放程度提高；致病性真菌分泌的丝氨酸蛋白酶可能是一种毒性因子。

Serine – The main sources of serine are radishes, garlic, onion, carrots, beetroots, celery, cucumber, mint, spinach, cabbage, alfalfa, papaya, apples and pineapples.

丝氨酸-的主要来源丝氨酸的萝卜，大蒜，洋葱，胡萝卜， beetroots ，芹菜，黄瓜，薄荷，菠菜，白菜，苜蓿，木瓜，苹果和菠萝。

But we don't care about Battlegrounds.

但我们并不在乎沙场中的显露。

Ah! don't mention it, the butcher's shop is a horror.

啊！不用提了。提到肉，真是糟透了。