查询词典 secretagogue

Aims/hypothesis Ideally, a therapeutic insulin secretagogue should coordinately increase insulin production and insulin secretion to maintain islet beta cell secretory capacity.

目的/假设：理想情况下，治疗用的胰岛素促泌剂应该同时增加胰岛素的合成与分泌来保持胰岛β细胞分泌的能力。

Wuhan, 430030, ChinaAbstract: Objective To investigate the relationship between the expression of growth hormone secretagogue receptorⅠa mRNA and GHS-RⅠb mRNA and the invasiveness of human GH-secreting pituitary adenomas and their clinical implication.

目的 检测生长激素释放剂受体 GHS-RⅠa mRNA 和GHS-RⅠb mRNA在GH腺瘤中的表达，探讨其与GH腺瘤侵袭性的关系，分析其临床意义。

Ghrelin,the recently discovered endogenous ligand for growth hormone secretagogue receptor,is widely expressed and involved in regulating diverse physiological functions in addition to stimulation of growth hormone secretion.

生长激素促分泌素是近几年才发现的生长激素促分泌素受体的内源性配体，ghrelin分布广泛，而且具有除促进生长激素分泌外的多种生理功能。

Objective: Patients with liver cirrhosis often have all kinds of incretionary and metabolic problems. Ghrelin is a novel endogenous ligand for the growth hormone secretagogue receptor involved in energy metabolism, glucose homeostasis and food intake.

目的：肝硬化患者常伴有多种内分泌和代谢紊乱，新发现的肽类激素ghrelin是一种生长激素促分泌剂受体的内源性配体，在调节能量代谢，血糖动态平衡和食物摄取中起重要作用；瘦素与肝硬化也有密切关系。

IntroductionGhrelin is a recently discovered peptide hormone and has been shown to be a natural ligand of the orphan growth hormone secretagogue receptor type 1 a(GHSR-1 a).

前言Ghrelin是近年来发现的生长激素促分泌物质受体(growth hormonesecretagogue receptor，GHSR)的内源性配体，其在心血管系统中的保护作用已成为人们关注的焦点之一。

In the October 18, 2005, issue of the Annals of Internal Medicine , Julio Rosenstock, MD, from the Dallas Diabetes and Endocrine Center in Texas, and colleagues reported on a 12-week trial of 309 patients with type 2 diabetes, no clinically significant respiratory disease, and hemoglobin A1c level of 8% to 11% who were receiving dual oral therapy with an insulin secretagogue and sensitizer.

Exubera的安全性与疗效已经在一项收纳超过2，500位第一型与第二型糖尿病成人病患的临床试验中评估；然而，Skyler表示，大部分的试验是比较饭前Exubera加上常规胰岛素，但在这种情况下，大部分专家会偏好使用快速作用的胰岛素相似物。

Structural analysis reveals that NAG73 has an intronless genomic sequence, which is homologous with the fourth exon and 3′UTR of Homo sapiens Growth Hormone Secretagogue Precursor Gene.

结构分析显示NAG73的基因序列无内含子，无典型的启动子序列， poly A尾。

The aim of the present study was to study the effect of nicotine on ghrelin and the growth hormone secretagogue receptor expression, the effect of ghrelin on vascular cell adhesion molecule-1(VCAM-1) and interleukin-8 (IL-8) expression in nicotine incubated human umbilical vein endothelial cell,and the possible signaling transduction mechanisms associated with PKC, p38 MAPK and NF-κB.

本实验通过观察ghrelin对尼古丁所致HUVEC VCAM-1及IL-8表达变化过程中PKC、p38 MAPK及NF-κ3的活性变化，并应用PKC、p38 MAPK及NF-κB的特异性抑制剂chelerytherine chloride、SB203580、PDTC，探讨ghrelin阻断尼古丁引起内皮细胞功能紊乱致AS作用的信号转导机制。

OBJECTIE—Pioglitazone, a peroxisome proliferator–actiated receptor agonist and glipizide, an insulin secretagogue, are commonly used to treat type 2 diabetes.

目的——吡格列酮是一种可活化过氧化物酶增值子受体激动剂，格列吡嗪为促胰岛素分泌剂，两者通常被用来治疗2型糖尿病。

This invention is directed to the-tartaric acid salt of 2-amino-N-{1-(2,4-difluoro-benzyloxymethyl)-2-oxo-2-3-oxo-3a-pyridin-2-ylmethyl-2-(2,2,2-trifluoroethyl-2,3,3a, 4,6,7-hexahydro-pyrazolo(4,3-c) pyridin-5-yl-ethyl}-2-methyl-propionamide which is a growth hormone secretagogue and as such is useful for increasing the level of endogenous growth hormone.

本发明涉及2－氨基－N－{1－－(2，4－二氟－卞氧甲基)－2－氧代－2－3－氧代－3a－(R－吡啶－2－基甲基－2－(2，2，2－三氟－乙基)－2，3，3a，4，6，7－六氢化－吡唑子基(4，3－c)吡啶－5－基－乙基}－2－甲基－丙酰胺的－－酒石酸盐，它是一种生长激素促分泌素，并且可用于提高内源性生长激素水平。

I am accused of being overreligious," she said in her quiet, frank manner,"but that does not prevent me thinking the children very cruel who obstinately commit such suicide.""

客人们在卡罗利娜·埃凯家里，举止就文雅一些，因为卡罗利娜的母亲治家很严厉。

Designed by French fashion house Herm è s, this elegant uniform was manufactured in our home, Hong Kong, and was the first without a hat.

由著名品牌 Herm è s 设计，这件高贵的制服是香港本土制造，是我们第一套不配帽子的制服。