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The transcriptional regulation of APP gene in neuronal cells may be important both as a model system for the analysis of transcriptional regulation of eukaryotic gene in neuron and playing the putatively central role of APP in the pathogenesis of the AD.

研究APP基因的转录调节，不仅可为真核基因在神经元中的表达调控提供一种模式，而且还可以进一步探讨其在AD病理学机制中的作用。

It is practical that using the spermatogonial cells as the vector to produce the transgenic mice of HBx and ras gene, and could play a role in establishing transgenic animal model of tree shrews.

以精原细胞作为载体，建立带HBx及ras基因的小鼠模型是可行的，为建立树的转基因动物模型的研究打下基础。

Based on observations in northern China, the microphysical process of precipitation formation and the role of ice crystal playing in those processes for three kinds of typical stratiform clouds are analyzed using rain category model.

通过建立层状云雨滴的分档模式，对中国北方常见的三类典型层状云降水形成的微物理过程以及冰粒子在降水形成中的作用进行了数值模拟。

Obviously, the medium properties, tectonic framework and deep process of the Western Himalayan Syntaxis strongly restrict and influence the tectonic structure and kinematic-dynamics responses in the north western margin and the western region of the Tibetan Plateau, and so that play an important role in the Tibetan dynamic model.

故在青藏高原的动力学模型构建中占有着重要地位。

However, Fermi resonance is an important role in the intramolecular vibrational energy transfer process, so we use the bend triatomic molecule model described by potential energy calculated from U(4) algebra, and the chaos of high excited molecular vibration can be studied by analyses of the intramolecular vibrational energy transfer process.

Fermi共振相互作用作为分子内能量转移的一种机制，在描述分子激发的完全振动方面有着重要的作用，因此，我们在构建弯曲三原子分子模型时引用了U(4)代数方法获得的势能面，从能量传递角度研究体系的混沌性质，是在多原子分子激发态领域研究非线性问题的合理延伸。

Krugman also deserves credit for outlining the basics of the "third generation model" of currency crises, in which unhedged foreign currency liabilities play a large role in causing and transmitting crises.

同时，克鲁格曼还建立了货币危机的&第三代模型&，在这个模型中，无套期保值的外国货币的债务，在导致和转移危机中，具有极大的作用。

One hand mechanical obstruct led to the increase of veinous resistance and the obstacle of microcirculation, the other hand the adhesive PMN was activated in excess, the white blood cells released a lot of enzymes, in which PMN-elastase can decompose the components of cell and many albumens, inclusive of immunoglobulin、alexin and fibrication. These components induced the injury of the pancreatic capillary vessels and cell and lysosome enzy made the tissue protein hydrolyze and produced unsaturated fatty acids, which destroyed the structure and function of cellar membrane. The inflammatory cellar factors activate other immunocytes to produce the injury and necrosis of tissue, which aggravated the pathological injury and led to shock、pyaemia and MODS. So ICAM-1 and LFA-1 played an important role in SAP. Frossard found that the expression of ICAM-1 in the rat model, especially in serum、pancreas and lung. All these showed ICAM-1 is an important factor in AP and concomitant lung injury.

胰腺小叶组织局部血管EC首先被激活，ICAM-1表达升高，与被激活的PMN表面表达的LFA-1相结合，&PMN-EC&相互作用加剧，一方面机械性阻塞毛细血管导致静脉阻力增加、微循环障碍；另一方面粘附的PMN过度吞噬或激活，当白细胞吞噬的颗粒不能被封闭隔离，连同细胞内的酶被释放出来，其中的PMN-elastase能够降解细胞基质中各种成分，水解多种蛋白，加重胰腺的毛细血管内皮细胞和腺泡的损伤；释放的溶酶体酶使组织蛋白水解，产生的不饱和脂肪酸引发脂质过氧化方应，破坏细胞膜的结构和功能；释放的炎性细胞因子，激发其他的免疫细胞的功能，导致进一步的组织损伤和坏死，加重SAP的病理损伤，最终导致休克、脓毒血症及多器官功能障碍等严重后果。

The more intervention of ethical care in management of community is bring important role into play in the aspect of exploring a new model of social management, especially in the aspect of congealing and integrating social centripetal force.

伦理关怀在社区管理中的更多介入，在探索新的社会管理模式方面，尤其在凝聚整合社会向心力方面发挥着重要作用。

Accounting firms in our country also needs to adjust the auditing objective according to the public 's requirement and the changes of auditing environment and put the new auditing model into use to raise auditing efficiency and CPA 's ability to discover the management fraud in order to lower auditing risk and exert CPA 's foreboded role in ensuring the sustainable healthy operation and development of securities market and furthermore exist and develop under the shock of the foreign accounting firms .

我国的会计师事务所也需要根据社会公众的需求和审计环境的变化，调整审计目标，运用先进的审计模式来提高审计效率，提高注册会计师发现管理层舞弊的能力，降低审计风险，更加有效地发挥注册会计师维护证券市场有序运行的作用，确保证券市场持续健康发展，并在外资会计师事务所的冲击下生存和发展，因此，有必要借鉴和应用国际先进的现代风险导向审计模式。

The dimensions used to measure business performance are: strategic business performance, service process improvement, service capacity, and employee satisfaction. The results indicate that CRM climate has significantly impact both on relationship quality and business performance. Among the CRM climate components, the organization management mechanism/HRM and the application domain of IT/IS play the main role in influencing the relationship quality and business performance. The link between organization management mechanism/HRM and trust is particularly strong. There also exists a prediction model between trust and business performance. It implies that trust is a very likely intermediating factor between CRM climate and business performance.

本研究除探讨CRM气候对关系品质、组织绩效之影响关系外，更以关系品质为组织绩效之预测变数；而研究结果发现：（1）CRM气候会正向影响关系品质、组织绩效，而关系品质亦会正向影响组织绩效，表示落实CRM气候确实能协助企业改善关系品质、提升组织绩效；（2）主要影响关系品质与组织绩效的CRM气候构面为「组织制度与人事」以及「资讯应用」（3）CRM气候会正向影响「信任」，且以「组织制度与人事」的解释能力最大；同时，「信任」亦正向影响整体组织绩效，显示「信任」为重要之关系品质因素。

However, as the name（read－only memory）implies, CD disks cannot be written onorchanged in any way.

然而，正如其名字所指出的那样，CD盘不能写，也不能用任何方式改变其内容。

Galvanizes steel pallet is mainly export which suits standard packing of European Union, the North America. galvanizes steel pallet is suitable to heavy rack. Pallet surface can design plate type, corrugated and the gap form, satisfies the different requirements.

镀锌钢托盘多用于出口，替代木托盘，免薰蒸，符合欧盟、北美各国对出口货物包装材料的法令要求；喷涂钢托盘适用于重载上货架之用，托盘表面根据需要制作成平板状、波纹状及间隔形式，满足不同的使用要求。