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One hand mechanical obstruct led to the increase of veinous resistance and the obstacle of microcirculation, the other hand the adhesive PMN was activated in excess, the white blood cells released a lot of enzymes, in which PMN-elastase can decompose the components of cell and many albumens, inclusive of immunoglobulin、alexin and fibrication. These components induced the injury of the pancreatic capillary vessels and cell and lysosome enzy made the tissue protein hydrolyze and produced unsaturated fatty acids, which destroyed the structure and function of cellar membrane. The inflammatory cellar factors activate other immunocytes to produce the injury and necrosis of tissue, which aggravated the pathological injury and led to shock、pyaemia and MODS. So ICAM-1 and LFA-1 played an important role in SAP. Frossard found that the expression of ICAM-1 in the rat model, especially in serum、pancreas and lung. All these showed ICAM-1 is an important factor in AP and concomitant lung injury.

胰腺小叶组织局部血管EC首先被激活,ICAM-1表达升高,与被激活的PMN表面表达的LFA-1相结合,"PMN-EC"相互作用加剧,一方面机械性阻塞毛细血管导致静脉阻力增加、微循环障碍;另一方面粘附的PMN过度吞噬或激活,当白细胞吞噬的颗粒不能被封闭隔离,连同细胞内的酶被释放出来,其中的PMN-elastase能够降解细胞基质中各种成分,水解多种蛋白,加重胰腺的毛细血管内皮细胞和腺泡的损伤;释放的溶酶体酶使组织蛋白水解,产生的不饱和脂肪酸引发脂质过氧化方应,破坏细胞膜的结构和功能;释放的炎性细胞因子,激发其他的免疫细胞的功能,导致进一步的组织损伤和坏死,加重SAP的病理损伤,最终导致休克、脓毒血症及多器官功能障碍等严重后果。

Objective To evaluate the possible role of alkaloid sinomenineon chronic rejection in rat heart transplantation model.

目的 探讨青藤碱对大鼠心脏移植慢性排斥反应抑制作用的可能机制。

During the postgenomics era the information about genomic sequence and gene functions provides a new foundation for evolutionary biology and ecology As the first whole-genome sequenced plant Arabidopsis thaliana and its wild relatives have played a critical role in understanding the evolution of genomics and speciation Both A halleri and A lyrata are closely related to the model species A thaliana A halleri ssp gemmifera occurs in northeastern China Japan and Taiwan; while its sister A halleri ssp halleri is mainly distributed in Europe Geographical barriers such as Tienshan Mountain Range isolate these intraspecific sisters Likewise A lyrata ssp kamchatica and ssp lyrata occur in East Asia and North America respectively Such distribution patterns seem to be consistent with allopartic speciation The comparison between ancestral and extant polymorphism by multilocus can be informative about the population genetics of speciation In this study we collected and analyzed DNA sequences of 98 genes from four wild relatives of A thaliana A halleri ssp gemmifera A halleri ssp halleri A lyrata ssp kamchatica and A lyrata ssp lyrata The ancestral states of these four species were compared to each other in terms of level of genetic variation However the ancestral species at the time of speciation were substantially more polymorphic than the extant geographical populations The observations are not fully compatible with speciation by strict allopatry At some species pairs parapatric speciation seems more reasonable in speciation of Arabidopsis The 98 gene sequences are also used for the congruence test between gene genealogy and species phylogeny Only 28 genes support the species phylogeny but there are 23 genes supports another major genealogy { lyrata} thaliana Based on the phylogenetic position change of A lyrata ssp kamchatica and Ks value for each species pair suggested the recent directional gene flow between A halleri ssp gemmifera and A lyrata ssp kamchatica

阿拉伯芥是第一个完成基因体定序的开花植物,其基因体资讯提供植物学研究的重要依据;在解析阿拉伯芥属物种的亲缘关系以及种化机制等重要的演化议题时,阿拉伯芥近缘的野生物种自然成了不可或缺的关键;跟阿拉伯芥近缘的物种包括A halleri及A lyrata,其中A halleri ssp gemmifera主要分布於中国东北、日本以及台湾,与近缘的A halleri ssp halleri其分布於欧洲隔著天山及大陆的障蔽,而A lyrata ssp kamchatica主要分布於东北亚及台湾,与分布於北美五大湖的A lyrata ssp lyrata被北极圈所分隔,这样的分布模式暗示异域种化的可能。藉由多基因分析比较祖先物种与现生物种遗传歧异度的相关可提供讯息探讨种化时期的族群遗传结构,本研究针对A halleri ssp gemmifera、A halleri ssp halleri及A lyrata ssp kamchatica、A lyrata ssp lyrata四个物种,两对互为亚种的姊妹群,以阿拉伯芥为外群进行研究,在四个物种完成98个同源基因的分子序列,利用套装软体MCMCcoal来估算祖先物种的遗传变异,亦估算现生物种的核苷酸歧异度,观察到?多物种配对中祖先物种遗传多型性大於现生物种DNA歧异度,显示异域种化模型并无法完全解释阿拉伯芥属物种的种化模式,在某些物种配对间邻域种化模式应比异域种化更为可能;在基因树与物种树的比较,98个基因片段的亲缘模式只有28个是与已知物种树一致的,有23个基因其树状图支持{ lyrata} thaliana的型式,藉由kamchatica位置的变化以及估算各物种配对间的平均同义置换率,推测在A halleri ssp gemmifera与A lyrata ssp kamchatica间具有近代的单方向基因交流。

The economic system played a active role in the early period of socialist construction and the anti-fascism war. While, the model of the Soviet Union was dogmatic and rigid.

新经济政策是社会主义经济理论创新历程上的第一个里程碑,但可惜由于列宁逝世过早,被他的继承者斯大林中断了。

The best models suggest that the topographic stress and the convergence forces of the adjacent plate are controlling factors on the active faults in Tibetan Plateau, and the drag force under the lithosphere caused by the convection of the asthenosphere material also plays an important role as the boundary condition of the model.

在考虑青藏高原地形附加重力作用和周边板块汇聚作用对现今大型断裂带运动特征控制作用的同时,岩石圈之下的橄榄岩软流圈至转换带物质对流对岩石圈的拖曳力也是必须考虑的底部边界条件。

Central Executive plays a key role in response inhibition,episodic buffer proposed in Baddeley new working memory model is where the feature binding happens.

4研究揭示了中央执行系统在刺激特征联合的反应抑制中的功能,支持由Baddeley(2000)新工作记忆模型中提出的情景缓冲器的假设。

The working memory model established by Baddeley and Hitch (1974) consist of central executive、 Visuo-spatial sketch pad and Phonological loop. Central executive play a crucial role that making our attention on the related information processing, inhibiting irrelevant information, responsible for the information to transform among various processes in the complex tasks.

Baddeley和Hitch提出的工作记忆模型由中央执行系统、视空间模版、语音环等成分构成,中枢执行系统具有核心控制作用,它保证大脑将注意集中在相关信息及加工过程上,而对无关信息进行抑制,负责在复杂任务中的各个不同过程间进行转换,对工作记忆中的内容进行监控等。

Our results suggest that adopting a bidimensional model of dependence more fully captures the theoretical domain of dependence, thereby permitting researchers to better examine its role in supply chain, channel, and marketing relationships.

我们的成果显示,采取二维模式的信赖可以更全面地刻画信赖的理论领域,从而允许研究者更好地研究信赖对供应链、渠道及市场关系的作用。

We can find from the research that the IR and XRD spectrogram shows the exists of H_3BO_3 on the surface of cellulose;there is H~+ released form the solution and the complexation proportion of the boric acid-glucose in the solution is 1:1, the boric acid-mannitol is 1:2 and the boric acid-N-methylglucamine is 1:2;and the half experienced mathematics model experiment on analyzing PH shows that the cellulose's adsorption of the boracic acid is mainly chemical adsorption with a proportion of 1:1 while physical adsorption with the H~+ released during the reaction plays a role as assistance.

研究结果表明,通过IR和XRD谱图分析,表明纤维素上吸附了H_3BO_3;硼酸和葡萄糖、甘露醇、N-甲基葡萄糖胺在水溶中络合比分别为1:1,1:2,1:2,同时溶液中有H~+释放出来;应用半经验数学模型分析pH值-浓度吸附实验,表明纤维素对硼酸主要以化学吸附为主吸附比为1:1,以物理吸附为辅,反应过程中释放出H~+。

However, in the long run evolution of capital structure, target leverage plays a more important role, which suggests that in the long term financing behavior of firms is more consistent with the dynamic trade-off model.

我们发现,在财务杠杆的短期波动中,融资缺口和股票市场状况是不可忽视的影响因素,而在资本结构的长期演变过程中,目标杠杆扮演着更加重要的角色。

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推荐网络例句

In the negative and interrogative forms, of course, this is identical to the non-emphatic forms.

。但是,在否定句或疑问句里,这种带有"do"的方法表达的效果却没有什么强调的意思。

Go down on one's knees;kneel down

屈膝跪下。。。下跪祈祷

Nusa lembongan : Bali's sister island, coral and sand beaches, crystal clear water, surfing.

Nusa Dua :豪华度假村,冲浪和潜水,沙滩,水晶般晶莹剔透的水,网络冲浪。