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The present dissertation reviews the total synthesis of biotin, particularly on Hoffmann-La Roche\'s Lactone-Thiolactone approach. The Lactone-Thiolactone approach is presently the most competitive commercial route, which gives an excellent illustration of the gradual construction of the functionalized skeleton with the simultaneous solution of the stereochemical issues in a minimal number of steps.In 1970, Gerecke etc. of Roche Corp.

论文对生物素全合成的文献进行了综述，重点讨论了目前工业上最有竞争力的内酯—硫代内酯路线，展示了生物素是如何以最少的步骤去逐步构建目标产物的官能团骨架并同时解决立体化学问题的。1970年，Roche公司的Gerecke等报道了一条通过手性内酯，以较高收率并保持构型得到手性硫代内酯，从而直接合成d-生物素的方法后，该中间体内酯(3aS，6aR)-1，3-二苄基。

This paper reviews a report about the first lot of rectifiers and thyristors, which were manufactured by NTD-Si (that is the stripeless silicon ), with high voltage and high current 30-years ago.

评述了30年前第一批用中子嬗变掺杂硅单晶制造高电压、大电流整流管和晶闸管的报道。

The paper sees Horton code as a primary characteristic value and generalizing condition of the river network, and selects, simplifies and generalizes river based on scale of before and after generalization,, The main contents of paper include:(1)Reviews generalization concept, arithmetic operators, methods, influence factor and frame of map generalization and design, analyze core theory of feature —oriented map generalization, discuss the main context and applicable method of river feature generalization(2) Summarizes natural form and spatial configuration characteristic of the river network, and describe the river network using digraph Paper mostly researches tree —like river, identifies the direction of river based on the angle of the main and secondary reach, and identifies the main river based on most length and predominant continuation of the flow direction along the major channel , then receives the grade of river by recursion and structuralize river network, builds hiberarchy rank system of river based on Horton coding(3)Designs the model of river network based on Horton code, and organizes the data of node, branch and river.

本论文把Horton编码作为水系网的一个主要特征值并以此作为综合条件，并根据综合前后的比例尺对水系网进行选取、化简和概括。论文的主要工作包括：(1)总结地图综合的概念、算子分解、实现方法、主要影响因素和总体设计框架，分析面向地理特征的制图综合的核心理论支撑，在此基础上讨论水系专题要素综合的主要内容和综合适用的方法。(2)总结水系网的自然形态和空间结构特征，用图论对水系网进行描述。以树状水系作为主要研究对象，依据树状水系的主支流交汇关系确定水系流向，依据水系中主流的长度最长和主流保持原有的流向趋势确定主流，按此递归得到河流的不同级别，对基于河段组织的水系网结构化，自动建立水系的Horton编码。(3)设计基于Horton码的水系网模型，对结点、河段、河流和河系的数据进行有效的组织。

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添加任何其他Stumbler给您的朋友清单，让您能够看到他的网页评论，这是交付给你下'的新'标签在您的StumbleUpon公司的个人资料。

You can show the gratitude towards any other Stumbler, if you really find something very useful, or if something that has appealed you big time, by writing Reviews on their profile.

您可以显示的谢意，感谢对任何其他Stumbler ，如果你真的找到一些非常有用的，或者一些已呼吁你大的时间，通过书面审查的资料。

This paper reviews the research and development of electrochemical synthesis of succinic acid at home and abroad.

综述了国内外电解合成丁二酸的方法，详细介绍了电解反应过程中阴极材料、阳极材料、电解槽结构和隔膜材料的发展趋势。

Zuckerberg's life so far is like a movie script. A supersmart kid invents a tech phenomenon while attending an Ivy League school--let's say, Harvard--and launches it to rave reviews.

扎克伯格迄今为止的经历就像拍电影一样：一个绝顶聪明的孩子读了一所好大学，而他却创造了一项技术潮流并且执着地去做。

I have written a series of short reviews of the major trends and surmised their application in health and medical information services.

我已经写了一系列短期审查的主要趋势和推测，其应用在健康和医疗信息服务。

The journal provides original research articles, reviews, reports, calendar of meetings and key symposia etc.

该杂志提供了原创论文、评论、报导、会议日程以及关键的座谈会等。

This paper reviews the GluR2-lacking AMPARs and their roles in the synaptic function and plasticity.

本文对GluR2缺失的AMPARs及其对突触功能和可塑性的作用作一综述。

She gently rebuff ed him, but agreed that they could be friends

她婉言拒绝了，但同意作为朋友相处。

If in the penal farm, you were sure to be criticized.

要是在劳改农场，你等着挨绳子吧！