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One may reach to the wrong side when estimate Mascot search results using decoy database search results.Therefore, protein database search algorithms and analysis of the results obtained by these algorithms should be studied more scrutinously.

因此,如何更好地提高蛋白质库搜索结果的准确率并提供更加可靠的分析方法需要得到更多的研究,第四章对蛋白质库搜索方法进行了展望。

Comparing with SEQUEST search results using the data generated by five types of mass spectrometers and the results obtained by different Mascot search parameters, it is found that SEQUEST and Mascot get different results when dataset and search parameters changed.

同时对由五种不同质谱仪产生的质谱数据的SEQUEST搜索结果,及不同参数条件下的Mascot搜索结果进行对比,发现在不同条件下得到的结果相差较大,并且在所有的结果中存在大量的错误匹配。

In the case of granite, observation results indicate that the extending routes of active cracks are mainly intercrystalline, transcrystalline, inter-transcrystalline, and intracrystalline. When the strain rate is low, the long intercrystalline cracks are prevailing, and with increasing of the strain rate, the short transcrystalline and intracrystalline cracks gradually increase. The statistic results show that the active crack density increases with increasing of the strain rate, and the mean length of active cracks diminishes with increasing of the strain rate, that is, the induced damage in comminuted product increases with increasing of the strain rate. For the first time this dissertation integrates macroscopic results of comminution with active crack growth under impact loading. It elucidates why the dynamic comminution strength of mineral beds increases with increasing of the strain rate through the active crack extending, and analyzes the influence of structure and constitution of minerals on their damage under impact stress. It is authenticated that both the size distribution and the damage population of comminuted product can be characterized by the fractal.

为分析料层颗粒在冲击下的细观损伤效果,采用德国生产的ASM68K半自动图象分析仪对粉碎生成物中的损伤情形进行了观测,以花岗岩为例,观测结果表明花岗岩颗粒在冲击应力下的活化裂纹扩展路径主要表现为沿晶、穿晶、沿穿晶和晶内等形式,在低应变速率下,活化裂纹以沿晶裂纹较多,随着应变速率的提高,其它裂纹形式大量繁衍,统计结果表明活化裂纹密度随着应变速率的增大而增大,活化裂纹的平均长度随着应变速率的增大而减小,综合表现为颗粒的细观损伤程度随着应变速率的增大而增大;首次将应力作用下的活化裂纹演化特征与粉碎的宏观效果相联系,并就料层动态粉碎强度随应变速率增大而提高的现象从裂纹演化特征的角度进行了解释;分析了矿岩构造结构特性对损伤产生和分布的影响。

Transudate samples from genital duct of the syphilis patient and 100 positive serum samples were detected by PCR. There was a 100% coincidence rate between the detecting results of the transudate samples and the clinical results. The detecting results of serum were all negative.

PCR检测29例梅毒患者生殖道皮损渗出液和100例初筛阳性血清标本,生殖道皮损渗出液与临床诊断符合率为100%,血清检测结果均为阴性。

The results showed that the conidia of the RNAi transformant accumulated more trehalose, lost viability more slowly during prolonged storage and showed reduced heat shock sensitivity than the wild type, and the overexpression transformant has reverse results. These results indicate that neutral trehalase in M.anisopliae control trehalose concentration via degradation of trehalose, and indirectly influnce the viability of conidia during prolonged storage and the resistance to heat stress.

以上研究结果表明,金龟子绿僵菌CQMa102孢子体内海藻糖是由中性海藻糖酶降解的,海藻糖含量与耐储性和耐热性具有正相关性,中性海藻糖酶在虫生真菌金龟子绿僵菌孢子中的生理功能是通过降解分子内海藻糖调控海藻糖含量,从而影响其对不良环境的抗性,如储藏性、耐热性。

Results The results showed that more accurate uniaxial modulus can be extracted using 4 parameters inhomogeneous triphasic model, and the predicted results appeared to match the experimental strain data better than other models.

结果 运用非匀质4参数三相模型可以提取更精确的软骨轴向模量,与其它模型相比,该模型对软骨膨胀的预测结果更接近实验结果。

The relationships of VEGF with the indices of renal damage, including renal/body weight, urinary protein excretion, glomerular volume and glomerular area, were analyzed. Results The expression of VEGF mRNA in diabetic kidney was significantly up-regulated after operation from 2 weeks to 24 weeks with the peak level at 20weeks, when compared with control at the same time- points. The positive results of VEGF staining in diabetic glomeruli was increasingly observed after operation from 2 weeks to 24 weeks, with the peak at 20 weeks. The positive results of VEGF staining in diabetic tubuli was increasingly seen from 2 weeks to 24 weeks, with the peak at 8 weeks.

结果 VEGF mRNA在糖尿病模型组大鼠肾脏中持续高表达,各时点与对照组相比差异均有统计学意义(P.05);糖尿病组2~24周肾小球VEGF蛋白表达强于对照组(P.05),24周时有所减弱,但仍强于对照组;糖尿病组各时点肾小管VEGF蛋白表达均强于对照组(p.05), 8周后表达明显增强;VEGF表达变化与肾质量/体质量(r=0.518, P=0.001)、尿蛋白(r=0.409, p=0.001)、肾小球面积(r=0.499, P-0.000)和体积(r=0.499, P-0.000)呈正相关。

Thirty-one papers did not describe the selection criteria clearly, 18 did not describe whether all the included patients were verified by using a reference standard of diagnosis, 36 did not describe whether the index test results were interpreted without knowledge of the results of the reference standard, 37 did not report the uninterpretable/intermediate test results, and 34 did not report the withdrawals from the study.

多数文献采用回顾性病例对照研究设计,其中31篇未清楚描述研究对象的选择标准,18篇不能确定是否所有研究对象均经金标准核实,36篇不清楚诊断试验结果的解释是否采用盲法,37篇未描述是否有难以解释的结果,34篇未描述是否有退出病例。

Methods:Retrospectively investigate(200809-200906) the cervix TCT results and vaginoscopy biopsy results in 6 934 patients.Patients with atypical squamous cellswere considered positive cases.The results were analyzed by statistics.

回顾性分析200809—200906月间6 934人次TCT检查结果与阴道镜活检病理学结果,不典型鳞状上皮细胞以上列为阳性病例,描述TCT检查结果与病理检查结果之的关系,并行统计学相关性分析。

The results of calculation were contrasted withmeasuring results in secondary breakup,and some valuable results were obtained.

根据这样的计算结果,本文得到了一些有意义的结论。

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