查询词典 replicon

Further studies also show that Dicer can inhibit the replication of the HCV subgenomic replicon.

进一步的研究显示Dicer能抑制HCV的亚基因复制子的复制。

EPO gene was inserted to an EBV replicon expression vector to form the plasmid pEPO, Renal anemia rat had been induced by feeding with adenine,and 450μg of the pEPO was delivered by perfusion into the rat peripheral circulation in the form of soluble DNA/galactosylate histone complex.13 days after injection,the number of peripheral red cells was counted and the concentration of hemoglobin was measured.

临床上常见的肾性贫血，其病因是肾脏因病理性损伤导致不能产生足够的EPO所致，目前治疗肾性贫血的方法是通过注射外源性重组EPO以促进红细胞的生成，但采用重组EPO进行治疗费用昂贵。

Several fragments containing the replication origin were cloned into replicon probe vector pUC-MEV constructed in this study. After screening a 4. 8kb PvuⅡ-SnaBⅠ fragment were determined to be the minimum replication region of the plasmid.

将包含复制起始原点在内的数个片段分别插入构建的嗜盐古生菌的复制子探针载体pUC-MEV中，通过筛选得到了pHH205最小复制功能片段。

Then the HCV subgenomic replicon cell model was incubated with Napp at concentration of 1mg/ml, 10~(-1)mg/ml, 10~(-2)mg/ml, 10~(-3)mg/ml, 10~(-4)mg/ml in cell culture solution and the negative and positive controls were set up correspondingly. After 3 days, the intracellular RNA of HCV subgenomic replicons were detected by FQ-RT PCR.

然后分别取终浓度为1mg/ml、10~(-1)mg/ml、10~(-2)mg/ml、10~(-3)mg/ml、10~(-4)mg/ml的Napp与含HCV亚基因复制子细胞培养液中共同孵育，同时设空白对照组和IFN-α2b阳性对照组，3天后用荧光定量PCR法检测HCV复制子中RNA的含量。

In order to confirm the influence of HCV persistent infection on IRF and type I interferon, HCV replicon cell (Huh7 cell line harboring subgenomic HCV replicons) was used.

结果发现，在NDV攻击下，Replicon细胞的IRF-7 promoter活性、内源性IRF-7和IFN-α表达水平均较Huh7细胞低(IRF-7 promoter活性上调倍数：2.54 vs 4.20，P＜0.001；内源性IRF-7mRNA表达水平：0.137 vs 1.671，P＜0.001；内源性IFN-αmRNA表达水平：0.246 vs 2.207，P＜0.001)。

It has been shown that the replicon has no significant impairment on the growth and metabolism of host cells.

复制子在人肝癌细胞株huh 7细胞株中能高水平的自主复制。

Our results demonstrate that alcohol stimulates HCV replicon expression at both HCV-RNA and protein levels.

我们的研究结果表明，酒精刺激丙型肝炎病毒复制子在丙型肝炎病毒核酸和蛋白质水平的双重表达。

It was reported that the EB replicon could harbor a DNA fragment of up to 330 kilobase pairs.

据报道EB病毒的复制子可以容纳长达330kb的dna片段。

Abstract］ Objective:To study the antiviral effect of ISG20 on HCV replicon.

目的：研究IFNα抗HCV的作用机理及了解ISG20是否参与介导IFNα对HCV的抑制作用。

Our data showed that two liver-abundant miRNAs can down-regulate HCV gene expression in HCV replicon cells.

结果显示有两个肝脏大量表现的miRNA过量表现时抑制HCV的表现。

In the United States, chronic alcoholism and hepatitis C are the most common ones.

在美国，慢性酒精中毒，肝炎是最常见的。

If you have any questions, you can contact me anytime.

如果有任何问题，你可以随时联系我。