查询词典 repeated trials

1 When planning trials, the sponsor should ensure that sufficient safety and efficacy data from nonclinical studies and/or clinical trials are available to support human exposure by the route, at the dosages, for the duration, and in the trial population to be studied.

5.12.1 当计划试验的时候，主办方应该保证能够得到足够的非临床研究和/或临床研究安全性和有效性数据，用来支持人体使用，包括路线，剂量，周期，试用人数。

Clinical trials in humans would be very difficult, however, because trials require many participants and there is no easy way to score effectiveness of a presymptomatic drug, Dr.

临床试验中，在人类将是非常困难的，但是，由于审判需要许多与会者并没有简单的方法来评分效力的presymptomatic药物，博士bezprozvanny说。

The basic procedures of the experiments were:(1)rule training:thisis pretraining in order to make subjects attend gradually to the numberdimension of stimuli,and master the rule of number matching.(2)formaltraining:a variety of cards loading number"3"or"5"served as samplesand comparisons.(3)transfer test,test trials were interposed among usualtraining trials of each session,the number is from 1 to 9,and three typestransfer test were proceeded.

两个实验的基本程序为：（1）规则训练阶段：用几个步骤使被试逐渐注意刺激的数维度，并掌握数目匹配原则；（2）正式训练阶段：数目3、5的多种变式作为样本和比较刺激，通过被试在各种样本和比较刺激对上的反应分析它们所利用的线索；（3）迁移测试阶段：将迁移测验随机插入每天的正式训练中，数目扩展为1至9，以验证被试数能力的抽象程度。

In each of the trials, sugarless gum was chewed 3 times a day after surgery, and the duration of chewing ranged from 5 to 45 minutes. One of the 5 trials involved patients with colorectal cancer.

在这些研究中，术后每天嚼三次无糖口香糖，且每次嚼的时间自5到45分钟不等，五项研究的其中一项收纳大肠直肠癌患者。

METHODS: Collaborative meta-analyses were undertaken of 194 unconfounded randomised trials of adjuvant chemotherapy or hormonal therapy that began by 1995. Many trials involved CMF (cyclophosphamide, methotrexate, fluorouracil), anthracycline-based combinations such as FAC (fluorouracil, doxorubicin, cyclophosphamide) or FEC (fluorouracil, epirubicin, cyclophosphamide), tamoxifen, or ovarian suppression: none involved taxanes, trastuzumab, raloxifene, or modern aromatase inhibitors.

对194个开始于1995年的关于辅助化疗或激素治疗的随机试验进行meta分析，许多试验包含了CMF(环磷酰胺、氨甲喋呤、氟尿嘧啶)，蒽环药物为基础的联合化疗比如FAC(氟尿嘧啶、阿霉素、环磷酰胺)或FEC（氟尿嘧啶、表阿霉素、环磷酰胺）及他莫昔芬或卵巢去势；无一包含紫杉烷类、赫赛汀、雷洛昔芬及芳香化酶抑制剂。

The above relation shows that a selection algorithm that selects individuals in proportion to their fitness actually allocates exponentially increasing trials to above- average schemata. In GAs, this process of allocating exponentially increasing trials to above-average schemata is carried out for a large number of schemata at the same time and is referred to as implicit parallelism Dozier et al.

上述关系表明，选择算法，选择个人中所占的比例分配给他们的健身成倍增加实际审判高于平均水平的图式在燃气这个过程中拨出成倍增加审判高于平均水平的模式进行了大量的图式在同一时间和被称为隐式并行

To ealuate the effects of psychological interentions on pain-related outcomes, Kerns and his team gathered data from 22 randomized trials published between 1982 and 2003. Trials were limited to adults with nonmalignant非恶性 low back pain that had persisted for at least three months.

为了评价心理介入对疼痛相关情况的作用，Kerns及其研究组收集了1982年至2003年间公开发表的22个随机临床试验数据，这些实验均限定在针对患有非恶性疾病，伴有轻度背痛的成年患者，且持续时间至少为3个月的研究。

For the sake of the safety of the human who take the new drug to cure the diseases, and the sake of advantages of the subjects who participate the clinical trials, since 1990s when the ICH-GCP was established, amended and meliorated, clinical trials in many countries in the world have developed into a regulatory era.

为了提高国内的临床数据规范化管理水平，尽快与国际的GCP规范和先进的临床数据管理规范接轨，真正能够获取高质量的数据而进行了本次研究。研究的目的：探索国内临床试验数据规范化管理软件系统的模式，及其该类软件系统在国内临床试验数据规范化管理中的应用价值。

Production department will carry out production trials with involvement from PE/Process Engineers and Quality control. All issues encountered during these Production trials are minuted.

生产部门连同项目工程师、工艺工程师和质量控制部门将进行试生产，在试生产过程中所遇到的所有问题将被记录保存。

However, there was significant heterogeneity in these trials, and the mean time to complete resolution was inconsistent across trials, precluding pooled analysis.

不过，这些试验有显著的异质性，各试验中，达到完整缓解的时间也不一致，而无法汇整分析。

Liapunov—Schmidt method is one of the most important method in the bifurcation theory.

Liapunov—Schmidt方法是分叉理论的最重要方法之一。

Be courteous -- even when people are most discourteous to you .

要有礼貌──即使当別人对你最不礼貌的时候。