查询词典 remodeling

Part 1: Correlation of aortic distensibility with concentric remodeling of left ventricle in patients with primary hypertensionObjectives: To explore the changes of aortic distensibility and its influencing factors and its relation with the concentric remodeling of left ventricle in patients with primary hypertension.

第一部分：高血压病患者主动脉扩张性改变与左室向心性重构关系探讨目的：通过观察高血压病患者主动脉扩张性的改变及其相关因素，探讨其主动脉扩张性改变与左室肥厚和向心性重构之间的关系。

Serum levels of TIMP-1 were gradually increasing with the progression of diabetic nephropathy,The results strongly suggested that TIMP-1 may contribute to vascular remodeling during the development and progression of high blood pressure and atherosclerosis. Meanwhile, TIMP-1 may mediate remodeling of glomerular basemment membrane and glomerulos-clerosi and plays an important role in the development and progression of diabetic nephropathy.

随着糖尿病肾病的病情进展，血清中TIMP-1水平逐渐增高，提示TIMP-1可能参与了糖尿病患者动脉硬化、动脉粥样斑块的形成及高血压的血管重塑过程；TIMP-1可能介导了肾小球ECM积聚，肾小球基底膜重塑、肾小球硬化，在糖尿病肾病发生、发展过程中起着重要作用。

Ventricular remodeling is one kind of self-perpetuating processes and the heart function will exacerbate to dysfunction finally if the ventricular remodeling is triggered.

由于心室重塑是一种不断自身进展的过程，当致病因素触发心室重塑后，心脏最终将走向泵功能衰竭。

The main determinants of systolic alular tenting were local left entricular remodeling, papillary-fibrosa distance and global remodeling indices.

收缩期瓣膜展开的预测变量包括局部左心室重构，乳头肌纤维膜距离增大和整体重构指数。

Areas of focus include the nervous system and hippocampal neurogenesis, along with the functional significance of pro-inflammatory cytokines, and the freeduan.com production of free radicals after brain ischemia; the digestive and integumentary systems, dealing with hepatocyte transplantation, pancreatic regeneration, and skin and hair regeneration; and the cardiovascular system, with repair and remodeling of the lung and heart, and arterial remodeling with bone marrow-derived progenitor cells.

焦点的地区包括神经系统和hippocampal neurogenesis，跟支持煽动性的cytokines的功能的意义，以及在大脑局部缺血之后自由基的freeduan.com生产一起；消化药和integumentary系统，处理hepatocyte移植，胰的再生和皮和头发再生；并且心血管系统，有修理和肺和心脏，和动脉与骨髓得到祖先细胞一起改塑的改塑。

Cardiac hypertrophy and extracellular matrix remodeling happened as a result of chronic overrange of pressure in heart and hypervolaemia which lead to damage of relaxation and compliance of heart.Drugs including renin-angiotensin converting enzyme inhibitor,angiotensin receptor blocker,aderergic receptor blocker,aldrosteron antagonism,tatins endothelin receptor blocker pancreatic kiniogenase and calcalium channel blocker,can delay or reverse the remodeling by several mechanisms.

主要表现为心脏在慢性超负荷的压力、容量作用下发生的病理改变致使左室肥厚组织胶原结构发生改变，导致心肌顺应性降低，舒张功能受到损害；作用于肾素-血管紧张素系统的药物及肾上腺素受体阻滞剂、醛固酮拮抗剂、他汀类药物、内皮素受体拮抗剂、胰激肽原酶、钙通道阻滞剂等药物通过不同途径和机制延缓和逆转左心室重构。

Therefore, collagen metabolism is the center of the extracellular matrix remodeling in intracranial saccular aneurysms, while the essence of the remodeling process is a kind of autoimmunological and inflammatory reaction.

因此，胶原代谢是囊性动脉瘤细胞外基质重塑的核心内容，而重塑过程的实质是一种以细胞免疫为主的免疫炎性反应。

The pathogenesis of asthma can be divided into three stages in immunology. The initial stage is sensibilization, which is closely associated with the activation of T cells. B7/CD28 and CD69 also play a significant role in this process. The second stage is chronic allergic inflammation. The immune dysfunction resulting from the disturbance of TH1/TH2 is a major cause of chronic allergic inflammation, and dominates asthma attack. And the third stage is airway remodeling due to chronic inflammation. Airway remodeling is one of the major causes of refractory asthma, which also contributes to the death from asthma.

哮喘的发病从免疫学角度可以分为三期：初期为致敏阶段，与T细胞激活关系密切，B7/CD28和CD69在这一过程也扮演重要角色；第二期为慢性过敏性炎症阶段，TH1/TH2失衡导致免疫功能紊乱是此阶段的主要原因，在哮喘发作过程中起主要作用；第三期为慢性炎症引起的气道结构重构阶段，是难治性支气管哮喘的重要发病和死亡原因。

The results suggested that vascular remodeling was the most prominent in LCA subjected to low shear stress accompanied by hypertension, which is regulated through the changing expression of p-Akt, p-p38, Rho GDIα. Tributyrin could affect the flow mediated carotid remodeling by both increasing apoptosis and decreasing proliferation of VSMCs through PI-3K/Akt, bcl-2, p53, p27. Tributyrin could have potential roles in treatment of vascular diseases, such as artherosclerosis and vascular restenosis, etc.

结果提示，高血压与切应力协同作用对血管重建的影响最为显著，Akt、p38和Rho GDIα信号通路参与了高血压与低切应力诱导的血管重建过程；Tributyrin对血管重建的干预作用是通过影响PI-3K信号通路，调节凋亡相关蛋白bcl-2以及细胞周期调控蛋白p53和p27的表达水平而实现的；Tributyrin有可能成为一种在动脉粥样硬化、血管再狭窄等疾病防治中有潜在临床应用价值的药物。

ConclusionG-Rb has protective effects on ventricular remodeling through improving systolic and diastolic function of cor sinistrum in ventricular remodeling rats,increasing anti-oxidase activity, reducing the damage of free radicals and vasoactive substance in myocardium and correcting disequilibrium of PGI2/TXA2 in ventricular remodeling etc.

结论G-Rb对大鼠心室重构具有保护作用，可能与其改善心室重构大鼠的左心收缩和舒张功能，增强抗氧化酶活性，减少自由基及缩血管活性物质对心肌的损伤，纠正PGI2/TXA2失衡等机制有关。

The absorption and distribution of chromium were studied in ryeusing nutrient culture technique and pot experiment.

采用不同浓度K2CrO4(0，0.4，0.8和1.2 mmol/L)的Hoagland营养液处理黑麦幼苗，测定铬在黑麦体内的亚细胞分布、铬化学形态及不同部位的积累。

By analyzing theory foundation of mathematical morphology in the digital image processing, researching morphology arithmetic of the binary Image, discussing two basic forms for the least structure element: dilation and erosion.

通过分析数学形态学在图像中的理论基础，研究二值图像的形态分析算法，探讨最小结构元素的两种基本形态：膨胀和腐蚀；分析了数学形态学复杂算法的基本原理，把数学形态学的部分并行处理理念引入到家实际应用中。