查询词典 receptors

When AT1 receptors are eliminated from the kidney, the residual repertoire of systemic, extrarenal AT1 receptors is not sufficient to induce hypertension or cardiac hypertrophy.

当从肾脏中去除血管紧张素Ⅰ受体，肾外的周身其余部分的血管紧张素Ⅰ受体不足以导致高血压及心脏肥厚。

Many studies reported suggest both neuronal precursor cells before innervation of target fields and the neurons of adult animal coexpress neurotrophic factors and their receptors, implying that autocrine and paracrine modes of NTFs exit. It has been observed that a number of neurotrophic factors and their receptors were expressed in cultured hippocampal cells and dorsal root ganglionic cells.

研究表明，无论是靶组织联系建立以前的神经元前体细胞，还是成年后的神经元，均有神经营养因子与其受体的共同表达，提示有神经营养因子自分泌和旁分泌存在的可能性。

NMDA(N-methyl-D-aspartate) receptors are a subtype of excitatory transmitters-glutamate receptor which belong to a heteromeric ligand-gated ionotropic receptors and play an important role in many complex physiological and pathological processes, such as nerve development, neuronal excitatory synaptic transmission, synaptic plasticity, central sensitization and neuronal death.

NMDA(N-methyl-D-aspartate)受体是兴奋性神经递质谷氨酸受体的一种亚型，是一种异聚体配体门控型离子通道，参与体内神经发育、神经元的兴奋性突触传递、突触可塑性、中枢敏化、神经元死亡等多种不同的生理和病理过程。

Glutamate is the major excitatory neurotransmitter in the mammalian brain and key mediator of intracellular communication, plasticity, growth and differentiation. NMDA receptors is one kind of Glutamate receptors. The N-methyl-D-aspartate receptor is a heteromeric ligand-gated ion channel that interacts with multiple intracellular proteins by way of different subunits.

N-甲基-D-天门冬氨酸受体是一种门控离子通道复合物，作为兴奋性氨基酸受体之一，主要分布于大脑皮层、海马、纹状体等部位，是兴奋性氨基酸递质传递的重要基础，同时是维持中枢神经系统功能正常的关键因素。

The transforming growth factor-β superfamily, a large group of highly conserved growth factors including TGF-βs, activins and BMPs, regulate a wide variety of cellular functions such as proliferation, differentiation, apoptosis and migration. Signals from these growth factors are transduced by a group of Smad proteins. To date, there are nine vertebrate Smads, including the receptor-activated Smads , Smadsl-3, 5 and 8, the common mediator Smad4 and Smad4β, and the inhibitory Smads, Smad6 and 7. Signaling is initiated when the ligand induces assembly of a heteromeric complex of type Ⅱ and type Ⅰ TGFβ receptors. Then R-Smads are directly phosphorylated by activated type I TGF-β receptors.

在多种SMADS中，SMAD5令我们产生兴趣，基于三个原因：1、Smad5基因敲除胚胎中发现卵黄囊的异位造血以及CFU-GM祖细胞数目增加，表明SMAD5可能是早期造血发育的负向调控基因。；2、应用反义核酸封闭Smad5可以逆转TGF-β对祖细胞增殖的抑制效应，表明它可能介导TGF-β信号转导，后者的异常，包括某些SMADS的功能异常，和白血病紧密相关；3、Smad5基因定位在人染色体5q21，此区域的缺失和急性髓系白血病和骨髓增生异常综合症相关，因此，Smad5被怀疑为白血病抑制基因。

NMDA receptor subunits express weakly at postnatal 7 days (P7),goes up at P14,reaches maximum level at P21,then remains this level until adult. Conclusion Neuronal functional NMDA receptors are composed of NMDA R1 and NMDAR2A in heteromeric configuration in the ventral horn of spinal cord;N MDA receptors may be involved in motor neuron maturation and plasticity during p ostnatal development.

NMDAR1和NMDAR2A是构成脊髓前角神经元功能性NMDA受体的重要亚基，NMDA受体可能参与生后早期运动神经元成熟或可塑性调控过程。

As for CD8~+ T cells,the 3-D reconstruction map and grayscale map, which imply the distribution mode/pattern of membrane receptors,also illustrate that CD8 and CD69 receptors inhomogeneously distributing on cell membrane and forming nano-/microstructural domains:5 Atomic force microscopy is a rapidly developing tool recently introduced into the evaluation of the age of bloodstains,potentially providing useful information for forensic investigation.

以红细胞为模型，测量了在室温、室外环境及低温等三个条件下，玻璃和云母基底上细胞形态学及膜表面粘附力随时间变化的关系。

Androgen receptors are not the master regulators for male behaviours, but rather, the researchers say, a "gain control mechanism" which amplifies such behaviours—or, when the receptors are absent, dials laddish behaviour down.

雄性激素受体不是雄性行为的主要控制因素，相反，这一行为是由&增益控制机制&加强的，换句话说，当受体减少时，好斗的欲望也会减弱。

Androgen receptors are not the master regulators for male behaviours, but rather, the researchers say, a "gain control mechanism" which amplifies such behaviours—or, when the receptors are absent, dials laddish behaviour down.

研究者说雄激素受体并不是雄性行为的主要调节者，相反的，是一个用来放大这些雄性表现的&获得控制机制&，或者是当雄激素受体不存在的时候，使这些雄性行为的表现减低。

The results of in situ hybridization and fluorescence quantitative PCR showed that the gene expression of dopamine receptors(including D1 and D2) in the prefrontal cortex and DRD1 in lentiform nucleus of SHR from the Kongsheng Zhenzhong Pill group is higher than that in the methylphenidate hydrochloride group and both groups are lower than that in the control group:the gene expression of dopamine receptors D2 in the lentiform nucleus from the methylphenidate hydrochloride group is higher than that in the Kongsheng Zhenzhong Pill group while both groups are lower than that from the control group.

原位杂交和荧光定量PCR表明，SHR大鼠前额叶皮质的多巴胺受体(包括D1和D2)和豆状核受体D1的基因表达，孔圣枕中丹组比盐酸哌甲酯组要高，且两者均低于对照组；豆状核多巴胺受体D2的基因表达，盐酸哌甲酯组要比孔圣枕中丹组高，且均低于对照组。

It has been put forward that there exists single Ball point and double Ball points on the symmetrical connecting-rod curves of equilateral mechanisms.

从鲍尔点的形成原理出发，分析对称连杆曲线上鲍尔点的产生条件，提出等边机构的对称连杆曲线上有单鲍尔点和双鲍尔点。

The factory affiliated to the Group primarily manufactures multiple-purpose pincers, baking kits, knives, scissors, kitchenware, gardening tools and beauty care kits as well as other hardware tools, the annual production value of which reaches US$ 30 million dollars.

集团所属工厂主要生产多用钳、烤具、刀具、剪刀、厨具、花园工具、美容套等五金产品，年生产总值3000万美元，产品价廉物美、选料上乘、质量保证，深受国内外客户的青睐