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We speculate that this is due to the highly specific bindingof sufentanil to spinal and supraspinal receptors.

我们推测这是由于苏芬太尼与脊髓和脊髓上受体的高亲和力。

These results, combined with the additional findings in decerebraterats, suggest that supraspinal effects (perhaps on -aminobutyricacid type A receptors) may have a supraspinal facilitatory effecton nociception for HFB.

上述结果结合在去大脑大鼠中的发现提示 HFB 的脊髓上效应（可能作用於γ－氨基丁酸 A 型受体）可能对伤害性感受有易化作用。

These findings suggest that NC (13-17) may play important roles in pain modulation at supraspinal level in mice and elicits these effects through a novel mechanism independent of the NC receptor and the traditional opioid receptors The bioactivity study of NC related peptide-NST showed that: NST could dose-dependently reverse the effects of NC in antagonizing EMs-induced analgesia; NST itself could increase the MAP and HVBR of rat, and the tension of rabbit isolated aorta muscle strips.

对孤啡肽相关肽—NST的生理活性研究发现，NST可以剂量依赖的拮抗NC对抗内吗啡肽-1和内吗啡肽-2的镇痛作用；NST对NC的降低大鼠平均动脉压作用无显著影响，但其本身可以升高大鼠的平均动脉压，后肢灌流压和离体血管条的张力，在心血管系统方面是一个新的生物活性肽。

Our observation indicates that capsaicin as a nociceptive chemical irritant can selectively activate primary afferent C-fibers to release SP and Glu from their central terminals in the superficial dorsal horn. It seems that the release of SP and Glu acting on NK-1 and NMDA receptors results secondarily in the activation of dorsal horn neurons, transmitting nociceptive information to supraspinal structures.

以上结果表明辣椒素作为一种伤害性的刺激源，可选择性兴奋C类传入纤维，引起其分布于脊髓背角浅层内的末梢大量释放SP和Glu，通过相应受体兴奋背角伤害性感受神经元，包括上行脊-丘束投射神经元，将痛觉信息传递至脑。

Many chemists focus on the design and syntheses of small molecular ligands of biological receptors.

用于研究生物受体的有机小分子配体的分子设计和合成已成为许多化学家研究的焦点。

It required spiking of postsynaptic tectal cells as well as activation of NMDA receptors, and effectively occluded long-term potentiation of retinotectal synapses induced by direct electrical stimulation of retinal ganglion cells.

这需要突触后顶盖细胞的脉冲和NMDA受体活化，并有效闭塞连接视网膜和中脑顶盖神经纤维的突触长期的增强，这是由视网膜活动中心细胞的直接电激诱发的。

As the first attempt, it was designed to reveal the general pattern of lectin receptor distribution on the surface of female cells, namely egg cells, central cells and synergids of Torenia fournieri and, especially, toensure the possible effects of cell isolation procedure on the distribution of lectin receptors by four different systems.

在烟草活体的中央细胞及卵细胞表面发现了伴刀豆凝集素受体的极性分布或者称之为&镶嵌性分布&。在大部分的中央细胞膜表面，该凝集素受体主要分布在靠近核的部位，而在相对侧的荧光要弱或缺失。

Therefore, fluorescein isothiocyanate conjugated lectins, namely concanavalin agglutinin, wheat germ agglutinin and soybean agglutinin, were used to localize lectin receptors on plasma membrane of male and female gametes and other relevant sexual cells, as well as embryos of various developmental stages of Nicotiana tabacum and Torenia fournieri by cooled charge coupled device and Confocal Laser Scanning Microscope.

从而证实：在本实验中用的几种酶组合对凝集素受体的影响并不大，即由酶解及解剖得到的雌性细胞的荧光在分布形式及强度上没有明显的差异；对比原位酶解与离体酶解得到的雌性细胞的荧光，证实机械操作对荧光的分布形式及强度也没有明显的影响。

In contrast, mutant and extracellular domain IL-1 receptors did not translocate to sites of cell adhesion and were unaffected by IL-1 stimulation.

突变型IL-1RI和细胞外段IL-1RI的融合蛋白表达后散布于细胞质内，对IL-1的剌激不产生反应。

Histoehemistry method was used to study the distribution of ulex europaeus agglutinin-l（UEA-1） receptors in rabbit uterus during the estrus cycle and early pregnancy.

采用组织化学方法对荆豆凝集素-1（ulexeuropaeusagglutinin-1，UEA-1）受体在兔发情周期及早期妊娠子宫内的分布以及激素调节进行了研究。

I am accused of being overreligious," she said in her quiet, frank manner,"but that does not prevent me thinking the children very cruel who obstinately commit such suicide.""

客人们在卡罗利娜·埃凯家里，举止就文雅一些，因为卡罗利娜的母亲治家很严厉。

Designed by French fashion house Herm è s, this elegant uniform was manufactured in our home, Hong Kong, and was the first without a hat.

由著名品牌 Herm è s 设计，这件高贵的制服是香港本土制造，是我们第一套不配帽子的制服。