查询词典 receptors

In addition, oxidoreduction potential of medium was regulated by addition of electron receptors or controlling the ratio of air to nitrogen. By optimizing the fermentation conditions of DA-1HB, 70 g.l-1 1,3-PD was produced and the molar yield of 1,3-PD from glycerol reached 69.9%.

4以1，3-PD合成性能占优的重组菌DA-1HB为工作菌株，调控培养基氧化还原态势，优化发酵工艺，以甘油为唯一碳源时，1，3-丙二醇合成浓度和摩尔得率分别达到70 g.l-1和69.9%。

Chronicity maybe result from many factors with complex mechanism.HCV may evade the host immune surveillance due to the hypermutation of HCV gene; HCV has the nature of pantropic,the tissues outside liver can provide virus for repeatedly infection of liver; The HCV receptors,such as CD81,LDL receptor,scavenger receptor B type I,L-SIGN,DC-SIGN and so on,may influence organism humoral immunity and the cellular immunity function in different degrees; HCV infection also may cause the reduction of quantity of organism immune cell or functional defect,low response of humoral immune response,tolerance of cellular immunity,then,the host finally transforms into chronic infection condition.

其慢性化的机制非常复杂，是由多个因素造成的，HCV因其基因高变性可以逃避宿主的免疫监视；HCV具有泛嗜性，肝外组织又可为肝组织的反复感染提供病毒来源；CD81、LDL受体、清道夫受体B类Ⅰ型及L-SIGN、DC-SIGN等HCV受体又可不同程度地影响机体的体液免疫和细胞免疫功能；HCV感染亦可直接导致机体免疫细胞数量减少或功能缺陷，体液免疫应答水平低下、细胞免疫耐受，宿主最终转变为慢性感染状态。

Objective To study the relationship between analgesic effect of total alkaloids in Papaver nudicaule and prostaglandins with opium receptors.

目的 研究野罂粟总生物碱的镇痛作用与前列腺素、阿片受体的关系。

The receptors of taste are embedded in the papillae and are sensitive to four basic flavours: sweet, salty, sour, and bitter.

这些味觉受器位于乳头中，对四种基本味觉敏感︰甜、咸、酸、苦。

There are four kind of isoforms of endothelin in human and other mammals named ET-1, ET-2, ET-3 and ET-β, which are slightly different in construction and pharmacological effect. In human beings, ET-1 is the dominative subtypes. ET-1 remains in blood at a low level about 5ng per liter on physical state. It is synthesized, stored, released and metabolized locally. The half-life of ET-1 is about 1 hour. ET-1 is the most potent vasoconstrictive factor till now, and it is more functional in vein than in artery. In vascular bed, there are two kind of ET receptors. Type A mainly located in smooth muscle cells, whereas type B in endothelial cells. The latter can stimulate intimal hyperplasia via a parasecretion way and activate some oncogenes such as c-fos and c-myc and then enhance their expression. These alterations result in constriction of blood vessels, thus the SMC steps into proliferate state from silent state.

人及哺乳动物体内有四种结构及药理学性质略有差异的异物体，分别为ET-1、ET-2、ET-3、ET-β，而在人主要是ET-1，在生理条件下，ET-1在血浆中含量较低，约为5ng〓，故ET-1不是一个循环激素，而是局部合成释放，局部起作用的活性物质，半衰期约1小时，ET-1是目前已知的最强的血管收缩剂，对静脉的作用比动脉强，在血管床，ET受体有A、B两型，A型主要分布在平滑肌细胞，B型主要分布在内皮细胞，它可以通过旁分泌途径刺激内膜增生，具有有丝分裂原效应，可以激活某些癌基因如C-fos、C-myc使其表达增强引起血管收缩，使静止期SMC进入增殖期，还可以通过信号传导途径，与bFGF、GTF-β、PDGF等生长因子协同作用，起共有丝分裂原作用。

The receptors of Periplaneta Americana compared with those ofAnomotaenia amaurornisus

苦恶鸟异带绦虫和美洲大蠊感受器形态比较

Working with global clients, Selexis offers contract development and maintenance of high-performance mammalian cell lines used in the expression of pharmaceutically relevant proteins (i.e. membrane receptors, MAbs, plasma proteins, rProteins in general).

与全球客户，提供合同Selexis发展和维护高性能的哺乳动物细胞系中使用的表达pharmaceutically相关的蛋白质（即膜受体，单克隆抗体，血浆蛋白， rProteins一般）。

To facilitate the applications of biologically functional protein in drug design, it is necessary to have a thorough understanding of their conformations and their interactions with the receptors. NMR spectroscopy has the unique ability to retrieve information about 3D structures of proteins and their interactions with the target proteins in solution. Many NMR techniques have been used to study a number of pharmaceutically important proteins and characterize their interactions with the targets. In this review, we will introduce these NMR methods and show how to utilize them for protein drug design.

为了设计具有生物功能性的蛋白质来当作药物，我们必须对其蛋白质结构与其受体在结合时的作用有完整清楚的了解，而核磁共振光谱具有独特的能力，可以获得溶液状态下蛋白质结构以及蛋白质与标的蛋白质交互作用间的资讯，目前已有许多核磁共振光谱技术运用到蛋白质药物的研究，并确认它们与其标的蛋白质间的作用模式，笔者将在本文中介绍这些技术，以及如何运用它们来获取重要资讯，俾设计蛋白质药物。

These assays can be easily adapted to other pharmacologically relevant receptors .

这些测定可以被简单的应用到药理学有关的方面。

Specific binding is found in tissues where muscarinic receptors are demonstrable pharmacologically .

在药理学方法证明有毒蕈碱样受体的组织中发现了特异的结合作用。

I am accused of being overreligious," she said in her quiet, frank manner,"but that does not prevent me thinking the children very cruel who obstinately commit such suicide.""

客人们在卡罗利娜·埃凯家里，举止就文雅一些，因为卡罗利娜的母亲治家很严厉。

Designed by French fashion house Herm è s, this elegant uniform was manufactured in our home, Hong Kong, and was the first without a hat.

由著名品牌 Herm è s 设计，这件高贵的制服是香港本土制造，是我们第一套不配帽子的制服。