查询词典 receptors

Objectives To study the effects of mifepristone on estrogen receptors and progestin receptors in human uterine leiomyoma and myometrium.

摘 要：目的了解米非司酮对子宫肌瘤及子宫肌层组织中雌激素受体、孕激素受体的影响。

According to senior author Howard Rockman, MD, also from Duke, the physical linkage of the receptors could allow physicians more flexibility in heart failure treatment. Because angiotensin blockers are better tolerated, they could be given alone to patients too sick to take beta-blockers. A single, potent drug targeting both receptors could reduce the need for multiple medications with increased potential for drug interactions and adverse events.

Howard Rockman指出，这些药物在治疗心脏衰竭的成效可以归因于它们并非以单一受体作为目标，这些研究结果也可以为心脏衰竭的患者订作药物疗法，不同受体的补体在不同患者及不同的疾病严重性之间有所差异，所以辨识患者单一性受体组成的血液试验，将可以让内科医生指定最适当药物治疗。

Results: VIP receptors and secretin receptors were demonstrated in tumor-free colon and colon tumors.

结果：无肿瘤结肠、结肠腺瘤、结肠癌、结肠癌肝转移灶组织均表达了VIP和胰泌素受体。

This thesis conclude 4 parts: 1 、 The change and effecting factors of plasma adiponectin level in old subjects with abnormal glucose tolerance; 2、 The distribution of adiponectin receptors in Wistar rat; 3、 The effect of fat-fed and pioglitazone on mRNA expression of adiponectin with its receptors...

本研究共包括以下四部分内容：1、老年糖耐量异常人群中脂联素的改变及其影响因素；2、脂联素受体mRNA在Wistar大鼠体内的分布；3、高脂饲养以及吡格列酮对大鼠脂肪组织脂联素及其受体表达的影响；4、吡格列酮对不同浓度脂肪酸培养的HepG2细胞脂联素受体mRNA表达的影响。

In addition, because these receptors have more binding points, they have better binding properties for anions than the molecular tweezer receptors based on thiourea we reported last time.

与以前我们报道的受体化合物相比，由于此类分子钳受体化合物具有更多的阴离子识别位点，因此具有更好地阴离子识别性能。

So far, the cancerogenic mechanism of lung cancer is not well elucidated. Some growth factors and growth factor receptors have been identified to participate in cancerogenic processes, but the downstream pathways regulated by those growth factor receptors are uncleared.

目前已知的癌症发病机理多是生长因子和生长因子的表面受体发生异常所致，因此，进一步阐明受体下游的调控基因对于阐明癌症的发生机理和进一步设计药物靶位点都是十分有意义的。forkhead box P4(FoxP4)就是本文作者在利用生物信息学方法筛选人类心脏发育候选基因的过程中发现的一个人类新基因，目前发现三种转录本。

It has been well established that agmatine is an endogenous agonist at imidazoline receptors and noncatecholamine ligand at alpha - 2 adrenergic receptors (α2- AR).

业已证明，胍丁胺是一种内源性的咪唑啉受体激动剂和α2-肾上腺素能受体（α2-AR）的非儿茶酚胺配基。

E. , ACTH antagonizes the analgesia mediated byμand δ opioid receptors, but notκreceptor;(2) The antagonizing effect of ACTH on opioid analgesia is proposed to be mediated by ACTH receptors, although the latter has not been characterized;(3) A contradictory interaction on intracellular cAMP content may constitute one of the postreceptor mechanisms underlying ACTH antagonism of opioid analgesia;(4) Another proposed mechanism of the anti-opioid effect of ACTH is that ACTH can modulate opioid-induced suppression of calcium influx;(5) ACTH has been shown to induce Fos protein expression in selected areas of the rat brain including the nuclei involved in pain regulation as well as the ependyma of the third ventricle and the aqueduct.

根据以上实验结果，本论文首次提出以下论点：（1）ACTH在脊髓水平对抗阿片镇痛具有受体选择性，即ACTH可对抗μ受体和δ受体介导的镇痛，不对抗κ受体所介导的镇痛；（2）由于ACTH与阿片μ受体的肽类配体的结合位点仅有很低的亲和力，与μ受体的非肽类配体的结合位点以及δ受体无亲和力，推测ACTH是通过中枢内的ACTH受体介导发挥抗阿片效应的；（3）ACTH抗阿片作用的受体后作用机制之一是在cAMP信使通路水平与阿片发生相互作用；（4）ACTH抗阿片作用的另一受体后机制是在〓水平影响阿片的效应；（5）通过Fos蛋白的诱导揭示：ACTH可以作用于脑内多个核团，其中包括许多与痛觉调制有关的核团，推测ACTH可能通过激活这些核团的神经元而发挥其中枢效应。

Recently we have focused on glutamate receptors, the major excitatory receptors in the brain.

而最近，该实验室又聚焦到大脑中一种最主要的兴奋性受体的研究——谷氨酸受体。

NMDA receptors are a subclass of excitatory amino acid receptors which play an important role in brain development, learning and memory processes.

NMDA受体是一种兴奋性氨基酸受体，在脑的发育、学习与记忆、脑缺血等机制中起重要作用。

It has been put forward that there exists single Ball point and double Ball points on the symmetrical connecting-rod curves of equilateral mechanisms.

从鲍尔点的形成原理出发，分析对称连杆曲线上鲍尔点的产生条件，提出等边机构的对称连杆曲线上有单鲍尔点和双鲍尔点。

The factory affiliated to the Group primarily manufactures multiple-purpose pincers, baking kits, knives, scissors, kitchenware, gardening tools and beauty care kits as well as other hardware tools, the annual production value of which reaches US$ 30 million dollars.

集团所属工厂主要生产多用钳、烤具、刀具、剪刀、厨具、花园工具、美容套等五金产品，年生产总值3000万美元，产品价廉物美、选料上乘、质量保证，深受国内外客户的青睐