查询词典 receptors

TGF-βbinds to a heteromeric complex of type I and type II receptors. The constitutively active type II receptor phosphorylates and activates the type I receptor which phosphorylates Smad2 and Smad3 (receptor-associated Smads). Receptor-associated Smads bind the common mediator Smad4 and are translocated to the nucleus, where they associate with DNA-binding cofactors to modulategene transcription.

TGF-β与其效应细胞表面的Ⅱ型受体TβRⅡ和Ⅰ型受体TβRⅠ形成的异源二聚体结合，相继激活TβRⅡ和TβRⅠ，活化的TβRⅠ再进一步活化Smad2和Smad3，磷酸化的Smad2/3必须与Smad4结合形成复合物，才能进入细胞核，调节靶基因的转录[6]。

Hexanedione; Schwann cells ;nerve growth factor; receptors, p75 neurotrophin

2，5-己二酮雪旺细胞神经生长因子受体，p75神经营养素

In present study, levels of dopamine 〓 and 〓 receptors and expression of the protein mRNAs in striatum were exarmined by the methods of immuno- histochemistry and in situ hybridization, respectively. It was found that mice treated by paraquat taken orally for four months displayed a marked hypoactive behavior.

本研究以口服给予小鼠百草枯的PD模型，采用免疫组织化学、原位杂交结合计算机图像处理分析技术，观察百草枯对纹状体区多巴胺〓受体、多巴胺〓受体蛋白含量和基因表达的影响。

Covers cells and tissues of the immune system, lymphocyte development, the structure and function of antigen receptors, the cell biology of antigen processing and presentation including molecular structure and assembly of MHC molecules, the biology of cytokines, leukocyte-endothelial interactions, and the pathogenesis of immunologically mediated diseases.

课程涵盖免疫系统的细胞和组织，淋巴球的发育过程，抗原受体的结构和功能，抗原反应过程的细胞生物学以及抗原的呈现，其中包括MHC分子的结构与组合，细胞激素的生物学，白血球和内皮组织的互动关系，以及免疫相关疾病的致病机转。

At present, the research about Heregulin-αand itsreceptors ErbB2 and ErbB3 was only the expression of them in mRNA and the impact ofHeregulin-αon the proliferation of mammary epithelial cells and milk proteins expression inculture. There were no results about the expression of Heregulin-αand its receptors in protein andthe impacts of Heregulin-αon the development, lactation and involution of mammary gland. It wasalso not clear about the signal transduction pathway of Heregulin-αin mammary gland.

目前对于乳腺中Heregulin-α及其受体ErbB2和ErbB3的研究仅限于其mRNA水平的表达以及Heregulin-α对培养的乳腺上皮细胞增殖和乳蛋白表达的影响，尚缺乏对乳腺中Heregulin-α及其受体在蛋白质水平上的表达变化规律以及Heregulin-α对乳腺发育、泌乳及退化的作用研究，正常乳腺中Heregulin-α的信号转导途径也不完全清楚。

It encodes a putative zinc finger transcription factor, and is a transcriptional corepressor for thyroid hormone receptors. Hairless gene plays a critical role in maintaining the delicate balance between cell proliferation, differentiation, and apoptosis in the hair follicle as well as in the interfollicular epidermis, and is concerned with the control of hair growth cycling.

无毛基因是与皮肤和被毛结构有重要关联的核受体基因，编码一个锌指结构转录因子，是甲状腺激素受体的转录辅阻遏物，并参与毛发生长周期的调控，在维持毛囊及毛囊间上皮的增殖、分化、调亡的精致平衡中扮演重要角色。

Two classes of renal sensory receptors have been identified neurophysiologically: renal mechanoreceptors responding to increases in intrarenal pressure and renal chemoreceptors responding to renal ischemia and/or changes in the chemical environment of the renal interstitium.

在电生理的研究下，有两类的肾脏感觉受体被发现，分别为：感应肾脏内压力的肾压力性受体；及感应肾脏缺血及肾内化学环境改变的肾化学性受体。

In conclusion, a catechol moiety is presumably to be essential for its activity and substitution of the p-hydroxybenzyl group at C-1 position with correct stereochemistry in the isoquinoline molecule makes a great contribution to the activation of beta adrenergic receptors.

本实验初步结果发现，对於去甲基乌药碱分子之药效，catechol基是必备无疑；而异喹啉环的碳－1位置上取代的p-hydroxybenzyl基对於药效有非常大的影响；至於其立体化学的配位是有立体选择性的。

In recent years,studies have revealed important roles of BAFF and its receptors in immune regulation of antibody isotype switching,germinal center maintenance,and T cell co-stimulation,that may provide new drugs in the future for the treatment of autoimmune disorders,lymphoma and B cell immunodeficiencies.

近几年来的研究表明，BAFF及其受体在抗体类型转换、生发中心维持、T细胞共刺激等方面发挥着重要的免疫调节作用，对自身免疫疾病、淋巴瘤和B细胞免疫缺陷的治疗具有潜在的应用前景。

This indicates that jawed and jawless vertebrates have developed antigen receptors independently.

综上所述，无颌类和有颌类脊椎动物应用不同的抗原识别系统完成适应性免疫反应。

I am accused of being overreligious," she said in her quiet, frank manner,"but that does not prevent me thinking the children very cruel who obstinately commit such suicide.""

客人们在卡罗利娜·埃凯家里，举止就文雅一些，因为卡罗利娜的母亲治家很严厉。

Designed by French fashion house Herm è s, this elegant uniform was manufactured in our home, Hong Kong, and was the first without a hat.

由著名品牌 Herm è s 设计，这件高贵的制服是香港本土制造，是我们第一套不配帽子的制服。