查询词典 receptors

Objective To investigate the expression of muscarinic acetylcholine receptors and GABAB receptors in lamina Ⅱ neurons in spinal cord.

目的观察M胆碱能受体亚型M2和B型γ-氨基丁酸受体在脊髓Ⅱ板层神经元的表达情况。

In addition, the compound of the invention having the antagonism to both receptors showed a better pharmacological action compared to the case where an antagonist selective to one of the receptors was solely used.

此外，对两种受体具有拮抗活性的本发明化合物显示出比单独使用对其中一种受体具有选择性的拮抗药的情况更好的药理作用。

The gamete is greatly specialized in the structure and function, and there are many kinds of agglutinin receptors in the plasma membrane, former studies indicated that the receptors may be associated with their roles in ovum recognition and fusion.

动物的精子和卵子是两类结构和功能均十分特化的细胞，其膜表面存在着多种凝集素受体，它们在精卵识别与融合中起着重要作用。

Such receptors are nerve cells that specialize in different senses. Thus there are receptors that detect heat, cold, itch, pain, taste, hunger, thirst, muscle ache, visceral sensations and so-called air hunger, the need to breathe.

这些感受器特异于某一种感觉，包括冷热感、痒、痛、味觉、饥饿、口渴、肌肉疼痛、内脏感觉以及空气感觉。

There was an obvious increase of insulin receptor gene and protein in the cerebral ischemia reperfusion tissues in rats. The positive cells such as neuron, neuroglia cells, vascular endothelium cells possibly participated in regulating the processes of energy metabolism of cells and neovascularization. It implied that the high expressions of insulin receptors in vascular endothelium cells in ischemic zones possibly participated in regulating the pathophysiological changes of the blood vessels in ischemic zones; The higher expressions of insulin receptors in different cells were possibly one of the self-protective machanisms in which the ischemic tissues confront the anoxemia injury.

脑缺血再灌注大鼠脑组织胰岛素受体基因和蛋白水平表达增加；半暗带区神经元、部分神经胶质细胞及血管内皮细胞等阳染细胞可能参与脑缺血后组织细胞的能量代谢、促新生细胞形成等病理生理调节过程；胰岛素受体在缺血区血管内皮细胞高表达提示其可能在缺血区血管的病理生理变化中起某种调节作用；胰岛素受体在不同细胞中表达增高可能是缺血脑组织对抗缺血缺氧损伤的自身保护机制之一。

Methods: We treated the experimental oral precancerous lesion in hamster's cheek pouch using 1023 Recipe (consisting of Radix Astragali, Gynostemma Pentaphyllum, Rhizoma Chuanxiong and selenium-rich green tea) for 6 weeks, and observed its effect in blocking cancer transformation, detected 2 kinds of agglutinin receptors (receptors of wheat germ agglutinin and Ricinus communis agglutinin) in the mucosa of the hamster's cheek pouch.

用1023中药合剂（由黄芪、绞股蓝、川芎、富硒绿茶组成），对仓鼠颊囊实验性口腔癌前损害进行为期6周的治疗，观察其对癌变过程的阻断作用，并对1023中药合剂用药组的活检组织进行2种凝集素（麦胚凝集素和蓖麻凝集素）受体的测定。

The affected chicks acquired the morphine conditioned place preference more quickly, and maintained it much longer. Experiment 3 showed that during E5-8, injecting delta receptor antagonist naltrindole reversed the learning and memory impairment caused by morphine while delta receptor agonist DPDPE impaired learning and partial memory function. On the other hand, mu opioid receptors had little effect. As for E17-20, given naloxonazine can reverse the increases of susceptibility to morphine, and the mu receptor agonist DAGO cause the increases of susceptibility to morphine. Delta receptors have no effect.

研究结果发现：经过对鸡胚发育不同时间段的吗啡给药，胚胎期发育E5-8阶段给予吗啡的小鸡学习记忆受损最为严重，表现为学习和记忆功能的严重下降；而E17-20时段吗啡给药的小鸡更容易获得吗啡CPP且保持时间更长。E5-8阶段给予delta受体拮抗剂natrindole能够翻转吗啡对学习和记忆的损害作用，并且给予delta受体激动剂DPDPE也损害学习和部分记忆功能，mu受体作用不大。E17-20阶段拮抗mu受体能够抑制成瘾易感性的增加，激动mu受体可以增加小鸡的成瘾易感性，delta受体没有明显作用。

Results: 1 The capacity of engulfment of A549 cells started enhancing at the 1h of preincubation with dexamethasone, reached the highest at the 4h of preincubation,At the 8h、24h of preincubation the capacity of engulfment evidently reduced. 2 Glucocorticoid cytosolic receptors antagonist RU38486 inhibited the improved engulfment ability by dexamethasone. 3Phagocytosing apoptotic eosinophils did not change the release of IL-6 and IL-8,but can inhibited the release of IL-6 and IL-8 from A549 cells stimulated by lipopolysaccharide. 4Increasely uptaking by dexamethasone also did not agitate the release of IL-6 and IL-8 from A549 cells. Conclusion: 1Dexamethasome improve the phagocyte capacity for apoptotic eosinophils of A549 cells by glucocorticoid cytosolic receptors, and the effect presents time-dependently. 2Phagocytosis of apoptotic eosinphils can degrade inflammatory reflection, so it is likely to be critical in the control of asthma inflammation.

结果： 1 A549细胞在地塞米松诱导后1小时吞噬能力开始升高，4小时吞噬能力达最高峰，8小时、24小时吞噬能力明显下降 2加入RU38486后抑制了地塞米松所增强的吞噬能力 3凋亡嗜酸粒细胞的吞噬并不能改变A549细胞释放IL-6和IL-8，但能抑制脂多糖刺激A549细胞后IL-6、IL-8的分泌 4地塞米松增加的吞噬也不激发A549细胞释放IL-6和IL-8 结论： 1地塞米松促进A549细胞吞噬凋亡的嗜酸粒细胞是通过A549细胞糖皮质激素胞浆受体发挥作用的，并且具有时间依赖性 2 A549细胞吞噬凋亡的嗜酸粒细胞能降低炎症反应，对哮喘炎症的控制具有重要意义

In others with double-armed receptors, the probes 4-(N,N-bisacetoxyethylaminomethyl)-7-methoxycoumarin.(B3) and 4-N,N- bis(diethylaminodithiocarboxyethyl aminomethyl-7-methoxycoumarin (B4) with pronounced fluorescence enhancement response to special heavy and transition metal ions were proposed as PET mechanism; for those with double-armed receptors following ICT mechanism, their performances are influenced by not only the structure of the receptors but also the attaching position of it.

双臂香豆素类荧光分子探针体系中，我们研究了含有不同杂原子的识别基团对PET型荧光探针识别性能的影响，优化了探针的选择性，得到了可以选择性识别某种过渡金属和重金属离子的荧光增强型分子探针4--7-甲氧基香豆素(B3)和4--7-甲氧基香豆素B4而在ICT型荧光探针的研究中，我们发现具有不同杂原子的识别基团可以对识别性能产生影响的同时，连接位置的改变也对识别能力有很大的影响。

Some stimulators, including viruses, tumor cells and hot shock, could promote the expression of NKG2 receptors and their ligands via activating certain transcription factors which are capable of up-regulating NKG2 promoters' activity. Meanwhile, epigenetic mechanisms including DNA methylation and histone posttranslational modifications are also critical to expression of NKG2 receptors and their ligands and may control the clonally distribution of some NK cell receptors.

病毒、肿瘤和热休克等刺激可以通过激活相应的转录调节因子，提高启动子活性而上调NKG2家族受体及其配体的表达，而启动子区DNA的甲基化状态、组蛋白的乙酰化和甲基化等表观遗传调控，在NK细胞受体及其配体的表达方面亦起重要作用，并决定NK细胞受体的克隆性分布。

It has been put forward that there exists single Ball point and double Ball points on the symmetrical connecting-rod curves of equilateral mechanisms.

从鲍尔点的形成原理出发，分析对称连杆曲线上鲍尔点的产生条件，提出等边机构的对称连杆曲线上有单鲍尔点和双鲍尔点。

The factory affiliated to the Group primarily manufactures multiple-purpose pincers, baking kits, knives, scissors, kitchenware, gardening tools and beauty care kits as well as other hardware tools, the annual production value of which reaches US$ 30 million dollars.

集团所属工厂主要生产多用钳、烤具、刀具、剪刀、厨具、花园工具、美容套等五金产品，年生产总值3000万美元，产品价廉物美、选料上乘、质量保证，深受国内外客户的青睐