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receptor site相关的网络例句

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与 receptor site 相关的网络例句 [注:此内容来源于网络,仅供参考]

Objective To explore the relationship between transforming growth factor-β1 and estrogen receptor with the occurrence of stress urinary incontinencethrough analysis on transforming growth factorβ1(TGF-β1) and estrogen receptor in paries anterior vaginase.

目的探讨绝经后压力性尿失禁患者盆底支持结构转化生长因子β1(TGF-β1)、雌激素受体与SUI发生的关系。

This dissertation for Ph. D. degree focuses on the design, synthesis and biological evaluation of novel active compounds against three important anti-metabolic drug targets, dipepetidyl peptidase IV, peroxisome proliferator-activated receptor γ, and farnesoid X receptor.

中文摘要本论文在综合运用传统药物设计理论、计算机虚拟筛选方法和现代有机合成技术的基础上,针对三个代谢类疾病的靶标进行药物设计、化合物合成与活性评价等研究工作。

The receptor binding experiment agreed to the result of Pettit's experiment, which suggested that Asp〓 and Gln〓were essential to receptor binding.

上述结果表明这二株突变体均保留了与受体结合的活性,这与Pettit等分析Asp〓、Gln〓对受体结合很重要的结论是一致的。

Protease treatment of the plasma membranes could abolish the binding but NaIO_4 and glycosidase could not, indicating that nsLTP144 bound to plasma membranes protein without carbohydrate moiety. Using the homobifunctional cross-linking regent bissuberate (BS~3) and rice plasma membranes incubated with ~(125)I-Trx-nsLTP144, we identified, after SDS-polyacrylamide gel electrophoresis and autoradiography, a putative protein receptor on the rice plasma membranes with the molecular mass around 60 kDa. NsLTP144 can not trigger extracelluar alkalization in arabidopsis, but can abolish the extracellular alkalization effect of phytopathogen elicitor cryptogein, suggesting that cryptogein and nsLTP144 may bind to the same membrane protein. In vitro pull-down assay showed that nsLTP144 interacted with OsCaM1, a possible extracellular calmodulin, implying that nsLTP144 and OsCaM1 could function in the same signal transduction pathway. These results shed light on revealing the roles of nsLTP in vivo and make it promising to finally characterize the plasma membranes receptor of nsLTP.

发现~(125)I-Trx-nsLTP144、~(125)I-Trx-nsLTP110与水稻细胞质膜均具有特异性结合,而且结合是饱和性的、可被竞争的,符合配体-受体结合的典型特征,同时用于对照实验的蛋白质~(125)I-Thioredoxin没有此特性,表明水稻细胞质膜上存在nsLTP的受体;利用可氧化糖基的NaIO_4和水解糖基的N\'-糖苷酶F处理水稻细胞质膜,再进行结合实验,结合活性几乎不受影响;而利用胰蛋白酶处理细胞膜则使得结合能力几乎完全丧失,表明其受体为没有经过糖基化修饰的蛋白质;利用交联剂BS~3交联配体一受体后,再进行SDS-PAGE分离和放射自显影,结果显示水稻细胞质膜上的nsLTP受体中有一个60kDa的蛋白质可以与nsLTP144发生特异性的结合,可能是其受体;细胞外碱化实验表明,nsLTP144不能促使拟南芥原生质体细胞培养液的细胞外碱化反应,却能猝灭来自植物病原菌的激发子Cryptogein刺激拟南芥原生质体产生的细胞外碱化反应,表明nsLTP和Cryptogein结合细胞膜上相同的位点,保护了植物细胞免受Cryptogein导致的细胞程序性死亡,并诱导系统获得性抗性的产生;体外Pull-down实验表明,nsLTP144和水稻的OsCaM1具有相互作用,暗示了nsLTP144和OsCaM1可能同在一个信号通路上起作用。

Considering together with our previous report about HSS regulation on EGF receptor, these results strongly suggest that the proliferatory effect of HSS on hepatic carcinoma cells is presumedly related with EGF receptor-mediated signal transduction.

鉴于我们已报道HSS上调EGF受体蛋白和基因表达这一事实,本实验结果进一步说明, HSS促人肝癌肝细胞增殖与其调节EGF受体介导的信号分子传导过程相关。

Objective It is to investigate the clinical significance of the expression of estrogen receptor and progesterone receptor in Endometrioid carcinoma.

目的研究雌激素受体、孕激素受体在子宫内膜样癌组织中的表达及临床意义。

The characteristics of quinazoline epidermal growth factor receptor inhibitors were briefly described in this paper, and the mechanism of receptor-tyrosine kinase inhibitor was also introduced. The synthesis of this kind of new compound was studied, and the synthetic route was redesigned and the method was modified.

本论文简述了受体酪氨酸激酶小分子抑制剂的发展概况,详细介绍了新型喹唑啉类表皮生长因子受体抑制剂,着重研究了该类化合物的合成,设计并打通了合成路线,同时又合成了25个新化合物。

Adrenergic receptor and rhodopsin have served as models for characterization of the mechanism of G protein coupled receptor desensitization.

2-肾上腺素受体和视紫红质受体作为模型的。

Methods NPE models of rabbits were made and H1 receptor antagonist (chlorpheniramine, H1 group), H2 receptor antagonist (Cimetidine, H2 group) or normal sodium were injected into PVN of rabbits utilizing the technique of stereotaxis. The degree of pulmonary edema was observed, the content of histamine in PVN was measured by high performance liquid chromatogram, and the ration of lung-water and A/P value were calculated.

制作家兔NPE模型;座用中枢立体定位技术,在家兔PVN微量注射组胺H1受体拮抗剂(扑尔敏,H1组)、H2受体拮抗剂(西米替丁,H2组)及生理盐水,现察肺水肿程度,高效液相法检测各组家兔PVN内组胺含量,测定肺水比、肺水肿液中蛋白含量与血浆蛋白含量的比值。

The authors demonstrate that signaling via the nuclear receptor liver X receptor couples sterol metabolism to proliferation of T cells.

这些结果表明LXR信号转导参与调节细胞增殖和免疫的代谢关卡。

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