查询词典 receptor site

The holding potential was -70mV.(2) By whole-cell voltage-clamp technique, after slices were preincubated with glycine receptor competitive antagonist alone or with GABA〓 receptor competitive antagonist alone or with GABA〓 receptor incompetitive antagonist alone or with GABA〓 receptor and glycine receptor competitive antagonists collaterally or with GABA〓 receptor incompetitive antagonist and glycine receptor competitive antagonist collaterally, the effects of 100μM propofol on EPSCs of the CA1 neurons of the rat hippocampus were investigated. The holding potential was -70mV.

2应用全细胞膜片钳技术，观察100M丙泊酚对单纯用甘氨酸受体竞争性拮抗剂预孵、单纯用GABA〓受体竞争性拮抗剂预孵、单纯用GABA〓受体非竞争性拮抗剂预孵、合用GABA〓受体和甘氨酸受体竞争性拮抗剂预孵以及合用GABA〓受体非竞争性拮抗剂和甘氨酸受体竞争性拮抗剂预孵的大鼠海马脑片CA1区电刺激诱发的EPSC的影响。

The anatomical localizations indicate that Al receptor and Dl receptor coexist in strionigro-strioentopeduncular neurons, and A2a receptor and D2 receptor coexist in striopallidals neurons. The heteromeric complexes of Al/D1、A2a/D2 receptor provided the molecular basis for the functional interactions of Al/Di and A2a/D2 receptor.

腺苷A1受体和多巴胺D1受体以及腺苷A2a受体和多巴胺D2受体分别共存於基底神经节中纹状体向黑质和脚内核投射的神经元以及纹状体向苍白球投射的神经元内。A1/D1、A2a/D2受体形成受体异聚复合体构成了受体一受体之间相互作用的分子基础。

Glycine receptor competitive antagonist partially reversed the effects of propofol. When slices were preincubated with GABA〓 receptor and glycine receptor competitive antagonists collaterally or preincubated with GABA〓 receptor incompetitive antagonist and glycine receptor competitive antagonist collaterally, 100μM propofol still decreased the amplitude of EPSCs.

2在膜钳制电压为-70mV条件下，100M丙泊酚明显降低合用GABA〓受体和甘氨酸受体竞争性拮抗剂预孵的大鼠海马脑片CA1区电刺激诱发的EPSC幅值，下降程度小于单纯甘氨酸受体竞争性拮抗剂预孵组，大于单纯GABA〓受体竞争性拮抗剂预孵组；而且，100M丙泊酚更是明显降低合用GABA〓受体非竞争性拮抗剂和甘氨酸受体竞争性拮抗剂预孵的大鼠海马脑片CA1区电刺激诱发的EPSC幅值，下降程度甚至大于单纯甘氨酸受体竞争性拮抗剂预孵组。

Although the intact-receptor based biosensors of the maxillary palp of cockroach Periplaneta Americana are not yet practical analytical devices at present. Yet, sensitive and selective responses to biomolecules involving amino acids and protein, as well as some simple substance such as salts and sugars have been firstly obtained. It is already evident that receptor based biosensors are enormously superior to isolated receptor biosensors in terms of response time and recovery times, thus, the intact receptor biosensor worth of further investigation and development.

总而言之，本论文首次从电生理信号上对美洲蜚蠊下颚须的化学响应进行研究，初步探讨了基于美洲蜚蠊下颚须的整合受体生物传感器的特性；发现了美洲蜚蠊下颚须能够整合其密集的感觉毛阵列对化学刺激的响应；得到了蜚蠊对氨基酸和蛋白质等生物分子以及简单物质如盐和糖等的敏感而具有选择性的响应信号，并发现了糖和蛋白质的特殊响应信号；表明了美洲蜚蠊下颚须是一种新型整合受体生物传感器的敏感材料，进一步深入地研究信号波形及其整合原理、探寻糖和蛋白质的特殊受体细胞等，对这一类型整合受体传感器的研究发展是很有意义的。

TGF-βbinds to a heteromeric complex of type I and type II receptors. The constitutively active type II receptor phosphorylates and activates the type I receptor which phosphorylates Smad2 and Smad3 (receptor-associated Smads). Receptor-associated Smads bind the common mediator Smad4 and are translocated to the nucleus, where they associate with DNA-binding cofactors to modulategene transcription.

TGF-β与其效应细胞表面的Ⅱ型受体TβRⅡ和Ⅰ型受体TβRⅠ形成的异源二聚体结合，相继激活TβRⅡ和TβRⅠ，活化的TβRⅠ再进一步活化Smad2和Smad3，磷酸化的Smad2/3必须与Smad4结合形成复合物，才能进入细胞核，调节靶基因的转录[6]。

Erve growth factor can combine with its" receptor (one of tyrosine protein kinase receptor coded by proto - oncogene tyrosine kinase, TrkA), Causing the molecule of receptors to gather on the cell surface, and the tyrosine protein in cytoplasmic domain may be activated, three tyrosine base in the kinase domain of its" receptor and two tyrosine base at other domain be phosphated, thus, phosphated tyrosine receptor kinase became the bracket which absorb all kinds of connective proteins and kinases.

GF与其酪氨酸受体激酶受体(由原癌基因trk编码的一种酪氨酸蛋白激酶受体，TrkA)相结合，引起受体分子在细胞表面发生二聚体化，然后受体细胞内结构上酪氨酸活性被激活，使受体自身结构中位于激酶结构域的三个酪氨酸残基及在此结构域外的两个酪氨酸残基发生自身磷酸化，这样，磷酸化的酪氨酸受体激酶A便成为吸收各种连接蛋白质和酶的支架。

It is included that 4-5 types of active sites exist in the catalytic system and the active site produced polymer with low molecular weight is easy to be activiated while TEA is used as the cocatalyst. While TIBA, the active site produced polymer with high molecular weight and seldom active site produced polymer with low one is prone to be activiated. MAO tends to activiate the active site produced polymer with middle-level molecular weight. In TEA-TIBA catalytic system, TEA and TIBA activiate the corresponding active site and the weight of every active site gradationally varied with the change of the ratio of the two cocatalysts. And the activity of the active site produced polymer with high molecular weight is proportion to the concentration of TIBA.

发现：TEA作为助催化剂时产生低分子量产物的活性中心易于活化，且体系中具有活性的活性中心有4～5种；TIBA易于活化产生高分子量的活性中心，基本上不能活化产生低分子量产物的活性中心；MAO对产生中等分子量产物的活性中心活化能力较强；在TEA-TIBA混合物体系中，TEA和TIBA各自对活性中心的作用表现为明显的互补现象，各活性中心的相对强度随着两种助催化剂之间的比例改变呈现渐次变化，其中产生高分子量产物的活性中心的相对活性(来源：c5AB3fC论文网www.abclunwen.com)与TIBA的浓度有明显的正相关性。

Visa, science and technology development Co, LTD Customer manager upervisor October 2006 to March 2008 Working location: xian Job responsibilities and performance: Customer manager marketing 6 number subordinates Mainly responsible for yahoo search for promotion and web hosting, domain name registration, suppositional mainframe, Responsible for employee training, orientation, regional sales team in the audience of the product sales plan and customers, Meeting with the marketing process design and implementation, Sales: Shaanxi worker international travel service website construction site construction and the domain name registration of space Poly million rosefinch international website construction site construction and multiplex domain registration of space Xian yuan and magnetic power limited company yahoo search for Xian fujian Lin sports Co, LTD, yahoo search for Xian Orient enterprise yahoo search for Xian metal Co, LTD is explained.the long website construction and yahoo search for Xian hualong chemical Co, LTD. Yahoo search for Xian han hospital website construction site construction and the domain name registration of space Xian made mountain hospital website construction site construction and the domain name registration of space Xian of technology Co, LTD BaoLin plant construction site construction site and the domain name registration of space Xian whoa outdoor shop website construction site construction and the domain name registration of space Beijing phoenix 42 ° hot yoga website construction and the domain name registration of space ... Education background Renmin university of China 2008 - today gaduate business administration management Airline worker xian university September 2004 - July 2007 E-commerce of management science and engineering college | xian in shaanxi Professional description: Management of electronic Commerce Department Training and experience Product marketing channels June 2008 Training: guanghua school age Training: The methods and channels of product marketing techniques The outstation of Beijing staff Network product sales skills August 2007 Training duration: two months City: xian Training institutions: yahoo's headquarters Training: Network product sales skills and yahoo's search for sales skills and case analysis Yahoo offices all sales.

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Majority of polymorphic sites and informative sites of Cyt b 433bp sequences of mirid bugs are located on the 3〓 site of triplet code, average 69. 09% of total polymorphic sites. The second number on the 1〓 site, averages 23. 64%. The 3〓 site is the most conservative one. The polymorphic site on this site averages only 7. 27%. Distrabution of the informative site is also under the same rule. Informative sites on the 3〓, 1〓 and 2〓 site of the triplet code average respectively 62. 85%, 22. 86% and 14. 29% of the informative sites.

盲蝽科昆虫Cyt b 432bp序列的多态性位点和信号位点大多数位于三联体密码子的第三位点，平均占总变异位点数的69.09％，其次是在第一位点，平均占总变异位点数的23.64％，第二位点最为保守，平均只占总变异位点数的7.27％，信号位点的分布规律也是如此，第三、第一、第二位点上信号位点所占平均比例分别为62.85％，22.86％和14.29％。

The properties of several rhodopsin sequences were analyzed by comparing withα2A-adrenergic receptor, and a great similarity was found between bovine rhodopsin andα2A-adrenergic receptor. Therefore transmembrane helices ofα2A-adrenergic receptor were constructed homologically based on the bovine rhodopsin.In the newly constructed structure, a 0.090 nm3 active-site, which was enclosed by several reported active residues, was found.

通过对比多个与α2A-肾上腺素受体同属G-蛋白偶联受体的视紫红质蛋白序列，选择以相似性最大的牛视紫红质蛋白为模板，同源模建了α2A-肾上腺素受体的跨膜结构，并在结构中找到了体积为0.090 nm3，已被报导的活性残基包围的活性位点。

"Bird Man's Diary, Butting on the Love Island", Changsha, China

2008年"鸟人日记，顶在爱情岛"，中国长沙

As long as they were in the service of a family of wizards, their magic would remain dormant.

只要他们一天为家庭服务，他们的法力就潜藏不动。