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Methods The rats were given with Huanggui enema by enemata and the paw swelling and pain threshold of rats were observed; the rabbits were given with Huanggui enema by enemata and the fever reaction of rabbits was observed.

用黄桂灌肠剂给大鼠灌肠,观察其对角叉菜胶所致大鼠足跖肿胀、大鼠痛阈值的影响。用黄桂灌肠剂给家兔灌肠,观察其对家兔发热的影响。

MethodsSixty Wistar rats were divided into 2 groups randomly: normol group(n=12), and model group(n=48).The model rats were fed with high fat-sugar diet for 6 weeks, then fed with adenine(100 mg·kg-1·d-1) and ethambutol(250 mg·kg-1·d-1) for 2 weeks to induce the IR and hyperuricemia model.

方法选用 60只成年Wistar雄性大鼠,随机分成正常对照组(12只)和模型组(48只),模型组给予高脂高糖饲料餵养6周,6周后再用腺嘌呤〔100 mg/kg·d)〕加乙胺丁醇〔250 mg/〕灌胃2周,造成胰岛素抵抗并高尿酸血症的大鼠模型。

MethodsSixty Wistar rats were divided into 2 groups randomly: normol group(n=12), and model group(n=48).The model rats were fed with high fat-sugar diet for 6 weeks, then fed with adenine(100 mg.kg-1.d-1) and ethambutol(250 mg.kg-1.d-1) for 2 weeks to induce the IR and hyperuricemia model.

方法选用 60只成年Wistar雄性大鼠,随机分成正常对照组(12只)和模型组(48只),模型组给予高脂高糖饲料喂养6周,6周后再用腺嘌呤〔100 mg/kg·d)〕加乙胺丁醇〔250 mg/〕灌胃2周,造成胰岛素抵抗并高尿酸血症的大鼠模型。

For evaluating anti-osteoporosis effect of Gukang oral liquid in eunuchized rats, sixty rats were randomly allocated to six groups:normal group,model group, three Gukang groups (with high, moderate and low dosages respectively) and tridin group.

通过切除大鼠睾丸骨质疏松模型,观察了骨康口服液不同剂量对骨质疏松大鼠的骨密度、骨矿含量及股骨骨生物力学的影响,并与特乐定作阳性对照。

The left common carotid artery to external jugular vein shunt operations were performed on experimental rats to establish left to right shunt animal models. The common carotid artery and external carotid artery of the control group rats were isolated without connection.

将实验组(n=9)大鼠的左侧颈总动脉与颈外静脉用套管进行连接,对照组大鼠仅切开颈部皮肤分别分离颈总动脉和颈外静脉后缝合皮肤,不进行血管连接术。

Methods: Twenty-four male Wistar rats were randomly divided into 2 groups: control group and model (high fat-fed) group. These rats were sacrificed at the end of 8, 12 weeks.

24只Wistar大鼠随机分为模型组和对照组(各12只),通过高脂饮食建立NAFLD大鼠模型,并在造模第8、12周末分批处死大鼠,同期设正常饮食组作为对照组。

Methods Forty-five Wistar male rats aged 5-6 weeks were randomly divided into control group, high fat-fed group and n-3 PUFA group. The rats were sacrificed after 11 weeks.

45只 Wistar雄性大鼠随机分为对照组、高脂饲养组和HF+n-3脂肪酸干预组。

Methods Thirty male rats were divided into 3 groups:control, high-fat fed, swimming group.The control rats were fed with common diet for 24 weeks.The high fat-fed group and swimming group were fed with high fat diet containing 55% saturated free fatty acid for 24 weeks . The swimming group began swimming for 50-60 minutes from 17th week to 24th week .The change of insulin sensitivity was valued by euglycomic-hyperinsulin clamp.

通过长期高脂高热量饮食喂养使大鼠具有胰岛素抵抗的特征,进行游泳干预治疗8周,高胰岛素正葡萄糖钳夹技术评价大鼠外周胰岛素抵抗程度,用RT-PCR检测大鼠骨骼肌肌肉素和GLUT4 mRNA表达的变化以及肌肉甘油三酯沉积度、胰岛素、血脂等代谢指标的差异。

An animal model of DM was established byinjecting a little dosage ofSTZ in high fat-fed rats. When the model was establishedsuccessfully, corresponding medicine were supplied for 12 weeks and then the ratsweight、biochemical criterions, blood glucose, GSP and the content of NO, ET, hs-CRP,AR, IL-6, TNF-a in rats serum were mensurated.

给药12周后,观察冬连胶囊对大鼠生长状态、体重、生化指标、血糖、糖化血清蛋白、血浆一氧化氮、内皮素、血清高敏C—反应蛋白、醛糖还原酶、白细胞介素—6(IL-6)、肿瘤坏死因子的影响,及大鼠视网膜微血管形态学、病理改变。

Methods40 rats were administrated intra-abdominally swine serum for 8 weeks to induce immune liver fibroses model.After 6 weeks treatment group were poured into gastra with Qinongtang and the serum were examined in rats.

方法采用猪血清注射法复制大鼠肝纤维化动物模型,利用大、小剂量芪蚣汤灌胃治疗6周,检测血清学指标。

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