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Methods 60 ANP rats induced by injection of sodium taurocholate into the pancreatic duct were divided into 3 groups: untreated group, TII treated group, and oliver oil control group. Another 6 normal rats were used as contral group.

将60只牛磺胆酸钠诱导的ANP大鼠分成不治疗组、雷公藤多甙组和橄榄油对照组共3组,另取6只正常大鼠作为对照组。

Male weanling Wistar rats were fed with either a basal selenium deficient diet (a Torula yeast based semisynthetic diet, containing Se 0.01 mg/kg) or a selenium sufficient diet supplemented with Se as Na\-2SeO\-3 (containing Se 0.5mg/kg). Rats were killed after different weeks(0,1,2,4,8,12,15,17,19,20 and 24 respectively).

以低硒酵母配制的低硒基础饲料(含硒量为0.01mg/kg)和在此基础上加亚硒酸钠配成硒水平为0.50mg/kg的足硒饲料来喂养雄性Wistar断乳大鼠。

Sixty SD rats were assigned randomly to the transplantation group (n=30) and the control (n=30). All animals were subjected to focal brain contusion following the Feeney's method. Then the neural stem cells derived from newborn Wistar rats were transplanted into the traumatically injured brains.

60只SD大鼠随机分配到实验组(n=30)和对照组(n=30),制作脑损伤模型,实验组将Wistar大鼠来源的神经干细胞移植到损伤灶,对照组注射等量生理盐水。

Methods Male NIH rats were treated with water containing 0.1% lead acetatic trihydrate for establishing an experimental lead poisoning rats model.

随着现代工业与交通的迅猛发展,环境中的铅污染日趋严重,特别是铅作业场所和城市空气中的铅含量已达到对人体产生严重危害的程度。

Methods Male NIH rats were treated with water containing 0.1% lead acetatic trihydrate for establishing an experimental lead poisoning rats model.

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Methods Male NIH rats were treated with water containing 0.1% lead acetatic trihydrate for establishing an experimental lead poisoning rats model.

方法取小鼠,饮水给予。1%三水合乙酸铅水溶液建立小鼠预防性铅目的评价QQL排铅口服液的促进排铅功能。

Methods Male NIH rats were treated with water containing 0.1% lead acetatic trihydrate for establishing an experimental lead poisoning rats model.

取小鼠,饮水给予0.1%三水合乙酸铅水溶液建立小鼠预防性铅中毒模型,同时灌胃给予不同浓度的受试物,喂养30天后测定血、肝脏和股骨中的铅含量。

Methods Fifty healthy SD rats were fed for twentytwo months in order to build the model of aging rats, the histology of femoral bone, tibial bone and lumbal vertebra was used to observe, then we evaluated the indexes which reflect the degeneration of intervertebral disc including the quantity of collagen type Ⅱ,Ⅹ of intervertebral disc by the immunohistochemistry methods, the relative area of vascular bud, the thickness of calcified layer and uncalcified layer on cartilage endplate and the indexes which reflect the osteoporosis including the thickness ratio of cortical bone, the relative area of bone trabecula, the bone density, the max stress and straining of bone.

50只健康纯种SD大鼠,喂养22个月,建立老龄大鼠模型,进行股骨、胫骨、腰椎等组织学观察,并评价椎间盘退变的相关指标(椎间盘软骨Ⅱ型和Ⅹ型胶原表达、软骨终板血管芽相对面积、软骨终板钙化层/非钙化层厚度)与骨质疏松的相关指标(骨皮质厚度指数、骨小梁相对面积、骨密度、骨最大应力和应变)的相关性。

Rats in the treatment group were injected with 10 μL of human insulin of rapid gene synthesis (1 ×10%5 U/L)immediately after unclamped the bulldog clamp and reperfusion, while rats in the sham-operation group and control group were injected with normal saline at the same volume.

分别于全脑缺血再灌注1,3,5d,假手术组(1只/时相点)、缺血对照组(6只/时相点)、胰岛素治疗组(6只/时相点)大鼠断头取脑,行免疫组化染色,光镜下观察海马CA1区神经元酪氨酸羟化酶和多巴胺-β-羟化酶表达的变化。

This implies that DNA methylation of promoter exon 1_7 may not underly the mechanism of GR up-regulation in GLP-1 -programmed rats.5 Hippocampal expression of GLP-1R and NGFI-A mRNAHippocampal GLP-1R (p =.009) and NGFI-A (p =.001) gene mRNA expression were significantly up-regulated in GP group as compared to VP group.Taken together, neonatal intramuscular injection of plasmid DNA encoding GLP-1 affects behavior and hippocampal GR expression in adolescent rats.

提示GR exon 1_7启动子区域DNA甲基化可能不参与GLP-1导致的GR转录上调。6海马GLP-1R和NGFI-A mRNA表达GP组大鼠GLP-lR(P=。009)和NGFI-A(P=。001)表达均显著高于VP组,表明肌肉注射GLP-1可能通过作用于其海马受体提高NGFI-A表达,进而调控GR表达。

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