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Water content and AQP4 of cephalophyma periphery 3h ICH group rats show no visible change, those of 6h ICH group rats and 24h ICH group rats change remarkably, those of 72h ICH group rats showes most significant different.

在3h组,脑组织含水量和AQP4升高不明显,脑出血6h后脑组织含水量和AQP4表达均明显增加,且在72h达最高,表明AQP4参与脑出血后脑水肿形成过程。

In that, the density of NMDA rece ptor of rats born to dam rats received morphine treatment were significantly l ess than the control rats on postnatal day 14 (PND 14). It suggested that rat s born to chronic morphine addicted dam rats could induce the neuronal NMDA re ceptor downregulation.

在过去本实验室已经证实,长期投与吗啡的母鼠所生的幼鼠脑中,N-me thyl-D-aspartate receptor (NMDA receptor,一种兴奋性胺基酸的接受体之一)的密度在出生后第十四天比起控制组有明显的下降。

Sixty male Wistar rats were randomly divided into the scalp clustery acupuncture group (25 rats), the model group (25 rats) and the sham group (10 rats).

将雄性Wistar大鼠60只随机分为模型组、头穴丛刺组各25只,假手术组10只,右颈内动脉插入线栓法建立大鼠大脑中动脉闭塞模型。

A total of 90 healthy male Sprague Dawley rats were selected for this study. Twelve rats were used for the sham operation group. Left anterior descending coronary artery of the remaining rats was deligated to establish models of myocardial infarction. After 24 hours of deligation, 36 rats were randomly divided into the control group and experimental group, 18 rat in each group.

目的:检测人胰岛素样生长因子Ⅰ基因修饰的鼠骨骼肌成肌细胞移植后,心肌梗死大鼠血浆及心肌组织内胰岛素样生长因子Ⅰ蛋白浓度的变化,以及心肌细胞内胰岛素样生长因子Ⅰ和端粒酶反转录酶mRNA水平的表达。

Of inward 〓 and outward 〓 were 2μmol·〓 and 3μmol·〓 respectively in normal rats, 10μmol·〓 and 14μmol·〓 respectively in hypertrophied rats.〓 of normal rats were larger than that of hypertrophied rats.

对正常大鼠内向电流及外向电流的〓分别为2μmo1·〓和3μmol·〓,对高血压肥厚大鼠内向电流和外向电流的〓分别为10μmol·〓和14μmol·〓,明显大于正常心肌。

Results Bro (0.5mg/kg, sc) reduced the PRL level and induced the dysplasia of mammary gland in lactational rats. Bro also caused the retardation of the weight growing in newly-born rats. l-tetrahydropalmatine 6 and 18mg/kg ip remarkably increased the prolactin level and promoted the development of mammary gland in lactational rats models and promoted the weight growing in newly-horn rats.

结果 sc Bro 0.5 mg/kg可显著降低哺乳期大鼠血清PRL水平,其仔鼠体重增长缓慢,并且母鼠乳腺组织发育不良。ip l-THP 6mg/kg及18mg/kg可显著提高用Bro造模的哺乳期大鼠血清PRL水平,促进其仔鼠体重增长,并且母鼠乳腺组织发育良好。

RESULTS: Totally 57 rats enrolled in this study, all animals completed Hot pain allergic symptom could not be observed on rats in experimental group during the whole experimental process, but continuously appeared in discharge percentage of nerve fibers at the central end of experimental rat sciatic nerve was remarkably lower than that of the control group 6.79%Sympathetic postganglion nerve fiber budding was not obvious in the slices of entire L4-5 dorsal root neuroganglion of injury side in 6 experimental rats,and basket-shaped cell could not be observed, but sympathetic postganglion nerve fiber budding was obvious in 2 rats in control groups with altogether 41 basket-shaped cells observed.

电生理实验:实验组大鼠坐骨神经中枢端的神经纤维自发放电百分数显著低于对照组(6.79%,46 7%)。③背根神经节切片荧光染色结果:实验组6只大鼠损伤侧L4-5的全部背根神经节切片中看不到明显的交感节后神经纤维芽生,没找到篮状细胞,而在对照组2只大鼠损伤侧L4-5的全部背根神经节切片中可看到明显的交感节后神经纤维芽生,共找到篮状细胞41只。

Then transplantation of the sciatic nerve from donor rats to the recipient rats in two groups were progressed.7 days after nerve transplantation,the contents of cd4 and cd8 in peripheral plasma of recipient rats were detected by flow cytometry.8 weeks after nerve transplantation,transplanted nerve were observed under light microscope.results:compared with nonirradiated group,the percentage of cd4 and the ratio of cd4 to cd8 in uvb irradiated group were significantly decreased(p<0.05,p<0.01),cd8 percentage was significantly increased(p<0.01).conclusion:uvb-irradiated donor splenocytes were injected in the recipient rats through caudal veil,which could induce immunological tolerance to allogeneic transplantation.

未照射组注射未经紫外线照射的供体脾细胞,照射组注射经紫外线照射的脾细胞,7 d后移植供体神经。术后7 d行外周血t淋巴细胞亚群检查,术后8 w行移植神经组织学检查。结果:照射组cd4+百分率、cd4+/cd8+比值较非照射组明显降低(p.01,p.05),cd8+百分率较非照射组明显升高(p.01)。组织学检查显示,照射组的再生神经较非照射组多。结论:尾静脉内注射经紫外线照射的异基因脾细胞可诱导对异体神经移植的特异性免疫耐受。紫外线;脾细胞;免疫耐受;坐骨神经

METHODS: Six rats were selected randomly for sham-operated from seventy-eight adult SD rats. The rest rats were divided randomly into two groups: LP-treated group, and NS-treated group. These rats were injured with Allen's weight-dropping model after seven-day peroral administration.

从78只成年SD大鼠中随机抽取6只作为假手术组,其余大鼠采用抽签法随机分成应用阿伐他汀的治疗组和应用生理盐水的对照组。

Fifty rats in the model group underwent ovariectomy, while the other 20 rats in the control group had sham operations. Three months later, 10 rats in the model group and 10 rats in the control group were selected randomly to detect their body weight, uterus weight, BMD of the left femur and lumbar vertebra, biomechanical characteristics of the left femur, levels of serum Ca2 +, Cr, ALP, SOD, MDA and GSH-Px and serumal resistance to OH(superscript -).

4个月龄雌性SD大鼠70只,随机取50只行双侧卵巢切除术,20只行假手术。3个月后随机从手术组和假手术组各取10只大鼠检测体质量、子宫湿重、左侧股骨及腰椎骨密度、生物力学特性和血清生化指标Ca(上标 2+)、肌肝、碱性磷酸酶水平,以确定骨质疏松模型建立成功。

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