查询词典 rats

By doing oophorectomy operations on 40 rats, fake operations on 10 rats, and non-operation on the rest of them as a normal group, the rats were randomly classified into four groups, 10 rats in each group.

将其中40只摘除双侧卵巢进行造模，10只行假手术，另10只不做处理作为正常对照组。

Methods The cognitive impairment rat model was induced by hypodermic D-galactose injection and half fat feeder (6 weeks), the Morris water maze was used to screen the model rats, which were divided randomly into 4 groups (12 rats in each group): the model group, the hydrochloricdonepezil group (0.4 mg/kg, weight, sic passim), the low-dose Huannao Yicong Fang group (7 g crude drug/kg), the high-dose Huannao Yicong Fang group (14 g crude drug/kg), they were treated respectively by intragastric administration. Besides, a control group of 12 rats was set up, they were given tales doses of distilled water. After 4 weeks, the behavior of the rats was detected, the contents of plasma P-selectin and PAI-1 were measured by ELISA, also the hemorrheology was measured.

采用皮下注射D-半乳糖及喂饲半高脂饲料（6周）的方法造成大鼠认知功能障碍，Morris水迷宫行为学测试确定模型成功的动物，随机分成四组（每组12只：模型对照组给予等量水，盐酸多奈哌齐组（0.4mg/kg，体质量，下同），还脑益聪方低剂量组（7g生药／kg），还脑益聪方高剂量组（14g生药／kg），同时灌胃给药，并设立正常对照组，给予等量水。4周后，对大鼠行为学检测，应用酶联免疫法检测大鼠血浆P-选择素及PAI-1含量和血液流变学各项指标。

Results:(1)Among 40 rats, 36 rats were successfully established and the rate of success is 90 percent;(2)All the successfully established models demonstrated polydipsia, polyuria and the body weight was not increased. 6 rats suffered cataract after 3 months, and 4 rats died in 6 months;(3)There was an approximately 61% loss of retinal ganglion cells in the central retina and the thickness of retina thinner under microscope ( P 0.01 ).(4) Electroscope changes include the thinner of retina, disorganization of the membranous disc of the rod cells and the thickness of basal membrane of vessal.(5)In normal group, 1 month dibetes mellitus and 1 month treatmen group, there was no expression of ERK1/ERK2 on the retina tissues. In 3 month diabetes mellitus group, the expression of ERK1/ERK2 was positive.

结果：①40只建模大鼠中36只建模成功，建模成功率为90%；②建模成功的大鼠都表现出多饮、多尿、消瘦、体重不增的表现，有6只大鼠在3个月后出现白内障，有4只大鼠在喂养接近至6个月时死亡；③HE染色光镜下6个月大鼠后极部视网膜节细胞层细胞数明显减少，减少约61%(P.01)，后极部视网膜明显变薄(P.01)；④电镜观察，视网膜变薄，视杆细胞膜盘紊乱，血管基底膜增厚等表现；⑤正常组、糖尿病组和治疗组1个月大鼠视网膜中未见ERK1/ERK2的表达，糖尿病组视网膜组织中3个月时可见少量表达，ERK1/ERK2表达部位为神经节细胞层和内核层；6个月时表达强阳性，部位表达不仅见于内核层、神经节细胞层，色素上皮层也见表达。

Methods A total of 45 rats were divided into three groups: control group, 15 rats, which consisted of normal controls; non-pinealectomy; sham operation; bipedal-rat pinealectomy group; a pinealectomy was performed in 20 bipedal rats; quadrupedalrat pinealectomy group: a pinealectomy was performed in 10 quadrupedal rats.

方法同时期出生后刚断乳的小白鼠45只，分成3组：对照组15只，其中包括正常对照组5只；非松果体切除双足鼠组5只：即单纯制作双足鼠，而不行松果体切除术；假手术组5只：即5只双足鼠除不切除松果体外其他与松果体切除术完全一致。

But whether the compound composed of them has suppressive effect on absence - like seizures of genetic tremor rats hasnt been reported. Furthermore, the animal models of investigating antiepileptic drugs were mostly induced by chemoconvulant or electrical stimulation. Since genetic factor is more primary in clinical epileptic patients, we used tremor rats fetched in from Japan as experimental animal models. We implanted electrodes in cortical and hippocampus of tremor rats and then recorded the electroencephalograms to observe effects of the traditional Chinese medicinal compound composed of Scolopendra, Bombyx Batryticatus, Uncaria and Arisacma Consanguineum on absence - like seizures in tremor rats.

而且以往多以化学致痫剂或电刺激等方法造模进行抗癫痫药物的研究，但在临床的癫痫患者中遗传因素占有相当大的比例，所以本实验应用了从日本引进的具有遗传性癫痫小发作的震颤大鼠作为实验动物模型，通过在震颤大鼠脑皮质和海马慢性安插电极后进行脑电图的记录，观察以蜈蚣、僵蚕、钩藤、制南星四味药为主的复方中药制剂对震颤大鼠癫痫小发作的抑制作用。

In order to inquire the causes of occurrence of lipoid pneumonia in rat that were raised in standard SPF animal reproductive area, we used self-reproducing standard SPF rats, male 50 and female 50. All of the rats were divided into 10 groups, raised in standard Barrier system, and fed the standard diets imported from U.S.A.. All animals were divided into 4 stages to sacrifice. Autopsy, histopathological and blood biochemical examination were made at each stage. The results reveal that no lipoid pneumonia were found to occur in the 5, 10 and 26-week-old groups of male and female rats. 40% of male and 60% of female were found to occur slight focal lipoid pneumonia in the 52-week-old groups of rats.

利用成大医学院实验动物中心生产的标准无特定病原大白鼠雌、雄各50只分成10组，在屏障系统中进行实验，使用美国进口的标准实验动物饲料餵食，在一年中分四期剖检，并做病理组织学及血液生化学观察，分析比较结果显示5，10及26周龄的雌、雄大鼠皆未发生类脂质性肺炎。52周龄雌大鼠有60%，雄大鼠有40%观察到患有轻度局部性类脂质性肺炎。

Compared with quinine stimulability, discharges of vagus efferent never in both CTA rats and control rats had no difference when sucrose stimulability was was given. 5 When the same sucrose stimulability was given, FLI neurons of SON and DMV in the CTA rats had much more expressions than that in the control rats.

5给予蔗糖刺激后，CTA组大鼠在SON和DMV内FLI神经元的表达较多，且表达远高于正常组大鼠；而且味觉厌恶建立后，蔗糖刺激和水刺激引起的SON核和DMV内FLI神经元的表达也有差异，蔗糖刺激引起的FLI神经元的表达要高于后者。

Methods Twenty-two adolescent SD female rats were selected. All rats were killed by dislocation of cervical vertebra, the eyeballs were in paraffin imbedding and made to a series of sections, using immunohistochemical method; ERα and ERβ distribution were investigated in uvea tissue of rats; and quantitied by Tanaka scores analytical method. The uteri of rats was used as positive control and PBS as negative control.

选择青春期SD雌性大鼠22只，采用颈椎脱臼处死大鼠，取眼球作常规石蜡包埋，连续切片， SP免疫组织化学方法显示ERα、ERβ在葡萄膜组织的表达；采用Tanaka记分法对ERα、ERβ进行定量分析，并设正常大鼠子宫作阳性对照；PBS代替一抗作阴性对照。

Methods Using Western ligand blot technique, the authors measured plasma levels of IGFBP-1-4 in uremic acidotic rats and uremic but without acidotic rats, in the non-uremic acidotic and pair-fed rats and also delermined liver mRNA in UA and UB rats.

采用Western ligand blot等方法，对随意进食组、尿毒症酸中毒组及其对照组尿毒症未合并酸中毒组、非尿毒症酸中毒组及其对照组无酸中毒组的大白鼠进行了血清IGFBP-1-4的测定，对UA、UB组肝脏IGFBPs mRNA进行了测定。

The purpose of this study was to investigate the effect of different doses o f dietary fiber of Tremella fuciformis Berk on lipid metabolism and inte stinal physiology in rats fed diets containing 1% cholesterol and 0.2% cholica cid. Forty-two male Wistar rats were randomly divided into six groups in a 2× 3 factorial design and were fed diets containing different doses (0%、5% or 10 %) of dietary fiber of TFB, with and without antibiotics 0.7g/100g of Nebaci tin (bacitracin: neomycin sulfate = 2:1,w/w) for 4 weeks. The parameters analyz ed included liver and serum lipid concentration , serum and caecal content of short chain fatty acids ,fecal neutral steroids and total bile acids content.T he results showed that rats fed the diet with antibiotics had lower levels ofs hort chain fatty acids in serum and caecal content than rats fed diet withouta ntibiotics.

中文摘要本研究乃欲探讨在有高胆固醇饮食条件下，摄取不同量的白木耳膳食纤维及添加抗生素对大白鼠脂质代谢及肠道生理的影响。42只 Wistar 品系雄鼠(重约260g)，随机分为六组，每组饲料中均添加 1%胆固醇及 0.2%胆酸，并以添加或不添加抗生素[ 0.7g Nebacitin(bacitracin：neomycin sulfate=2：1，w/w)/100g dry matter] 、白木耳膳食纤维量(0%、5%或 10%)作 2×3 factorial 之实验设计，实验期四周，分析血清及肝脏中脂质浓度，血清及盲肠内容物短链脂肪酸浓度，以及粪便中总中性固醇，总胆酸的含量。

According to the clear water experiment, aeration performance of the new equipment is good with high total oxygen transfer coefficient and oxygen utilization ratio.

曝气设备的动力效率在叶轮转速为120rpm～150rpm时取得最大值，此时氧利用率和充氧能力也具有较高值。

The environmental stability of that world - including its crushing pressures and icy darkness - means that some of its most famous inhabitants have survived for eons as evolutionary throwbacks, their bodies undergoing little change.

稳定的海底环境─包括能把人压扁的压力和冰冷的黑暗─意谓海底某些最知名的栖居生物已以演化返祖的样态活了万世，形体几无变化。