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Methods Wistar rats of 6 months old were randomly divided into normal control groupand IR group. Each group had eight rats. Euglycemic insulin clamp technique was used to determine IR and glycose infusion rate was used to IR. Cardiocyte apoptosis was evaluated by TUNEL. Heart weight and body weight were measured to calculate HW/BW. Fine structure of heart and ultramicrostructure of cardiocyte were observed.

6月龄Wistar大鼠,分为正常对照组和IR组,正常血糖胰岛素钳夹技术测定各组大鼠IR,葡萄糖输注速率表示IR情况;测量大鼠心脏重量和体重并计算心脏重量与体重之比;原位末端酶标记法检测各组大鼠心肌细胞凋亡情况;观察心脏微细结构和心肌细胞超微结构;免疫组化检测心脏间质Ⅰ、Ⅲ型胶原水平。

Rats of pancephalic ischemia and reperfusion were establ- ished with gyral vessel closing method by pulsinelli. SOD and MDA in cerebral tissue, transmitter content of catecholamine in hippocampal gyrus. striatum and neocortex, and patho- morphism of cerebral tissue of experimental animals were stu- died by piercing Baihui to Qubin of rats with filiform needle.

本课题采用Pulsinelli四血管关闭方法建立大鼠全脑缺血再灌注模型,对比观察了毫针透刺大鼠百会至曲鬓穴区对实验动物脑组织中SOD、MDA,海马、纹状体、新皮层中的儿茶酚胺递质含量及脑病理组织形态等方面进行研究。

Methods: Thirty male SpragueDawley rats were randomly divided into 5 groups, group A 3 days after L5 VRT, group B 7 days, group C 14 days, group D 21 days and group E of sham operation, whose left spine cords were exposed by hemilaminectomy. Rats in each group were respectively perfused with paraformaldehyde and materials were taken from L5 dosal root ganglions and the changes of expression of P2X3 receptor were observed with immunofluorescence staining.

雄性SD大鼠30只,随机分为5组(n=6),A组(L5 VRT术后3 d)、B组(L5 VRT术后7 d)、C组(L5 VRT术后14 d)、D组(L5 VRT术后21 d)模型组和E组,E组仅行半椎板切除术暴露左侧脊髓,分别在各自的时间点灌注取材L5背根神经节,用免疫荧光染色方法观察P2X3受体表达的变化。

Experiments employing ovarietomised rats treated or untreated with hexoestrol dipropionate also showed that uteri from rats in artificial ...

讨论了雌性激素处理过的大白鼠应用于脑垂体后叶检定的可能性,和可能影响检定结果的因素。

Results:Compared with normal rats,both hexosamine and phospholipids in gastric mucosa of rats under celiac seawaterimmersing trauma are progressively decreased(P0.05),especially in stress 3h group.

结果:与正常组大鼠相比,腹腔浸泡伤组大鼠胃黏膜氨基己糖和磷脂随着浸泡时间的延长而进行性减低(P<0.05),并在3h时达最低。

Methods:Thirtytwo rats were randomly divided into four groups(normal control group,celiac seawaterimmersing trauma stress 1,2,3h groups).The amount of hexosamine and phospholipids in gastric mucosa of rats were detected by both chemochromometric and modified chemical methods.

32只SD大鼠随机分成正常对照组和腹腔浸泡伤1h、2h、3h 4组,分别取相应大鼠的胃黏膜,采用化学比色法和改良抗坏血酸法测定胃黏膜中氨基己糖和磷脂含量。

Results:Compared with normal rats,both hexosamine and phospholipids in gastric mucosa of rats under celiac seawaterimmersing trauma are progressively decreased(P0.05),especially in stress 3h group.

海水浸泡伤是一损伤性因素,通过减低胃黏膜中氨基己糖和磷脂含量而损害腹腔浸泡伤的大鼠胃黏膜屏障。

Results CsA clearly decreased creatinine clearance and increased urinary excretion of N-acetyl-β-D-glucosaminidase in rats as compared with those in the vehicle group. Morphologic changes consisted of vacuolization of tubular cell, expansion of the interstitium and interstitial fibrosis, hyalinization of afferent arterioles. Severity of the injury was related to the dosage of CsA. Striped interstitial fibrosis and arteriolopathy were more severe in the rats treated with CsA and low-salt diet than with CsA and normal diet.

结果 用CsA的大鼠出现尿量增多、内生肌酐清除率下降、尿N-乙酰-β-D-氨基葡萄糖苷酶排泄增多等;病理上表现为不同程度的细胞浊肿、空泡变性及灶性分布的间质纤维化和小动脉病变,随CsA剂量的增加,病变呈加重趋势;结合低钠饮食,CsA慢性肾毒性病变明显加重。

VDR protein expression is higher in GHS rats than in normocalciuriccontrol rats ,which may contribute to the intestinal calcium hyperabsorption.

结论遗传性高钙尿性结石大鼠十二指肠粘膜维生素D受体蛋白的表达增强,这可能与GHS鼠十二指肠对钙的高吸收密切相关。

The hyperalgesic effect induced by intrathecal injection of atosiban might be more profound in rats with ligation than in rats with inflammation. The results revealed that the roles of endogenous and exogenous oxytocin are different in different pain models.

不同痛觉模型间催产素镇痛作用的比较鞘内注射催产素所引起的镇痛效应从弱到强的顺序是:正常大鼠、炎症痛大鼠、神经损伤性痛大鼠。

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