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The study showed that self-blood injection could improve the IFN-γin asthmatic rats and restrain expression of IL-4. That meaned it could correct the disproportionality of Thl and Th2 in asthmatic rats and it could be one of the important mechanisms of the treatment of self-blood injection.

研究结论经络注血疗法能提高哮喘大鼠IFN-γ含量,抑制IL-4的表达,即对卵蛋白所致哮喘大鼠Th1/Th2的比例失调有纠正作用,是经络注血疗法治疗哮喘的重要机理之一。

Objective: The aim of the study was to observe the change of the IFN-γand IL-4 in the asthmatic rats blood after self-blood injection so that to explore the influence of disproportionality of Th1 and Th2 in asthmatic rats, and hoped it could provide an experimental evidence so that to guide the treatment of self-blood injection with the asthma patients.

研究目的通过观察哮喘大鼠自血肺俞穴注射治疗后外周血IFN-γ和IL-4的变化,探讨经络注血疗法对哮喘大鼠Th1/Th2细胞失衡的影响,探讨经络注血疗法对哮喘大鼠症状的改善,为经络注血疗法治疗哮喘提供实验依据。

Results Qidan Granules could relieve the pain caused by glacial acetic acid and heat stimuli; significantly inhibit the oxytocin-induced dysmenorrheal in mice; It also showed obvious inhibitory effects on the increased capillary permeability induced by glacial acetic acid, carrageen-induced toe edema in rats and dimethylbenzene-induced ear swelling in mice, and cotton pellet-induced granuloma formation in rats. It could also significantly inhibit oxytocin-induced dysmenorrhea in mice.

结果 奇丹颗粒能明显抑制乙酸和热刺激所致的小鼠疼痛反应;对缩宫素所致实验性痛经小鼠具有良好的镇痛作用,对乙酸所致小鼠腹腔毛细血管通透性增高以及大鼠角叉菜胶足趾肿胀、二甲苯所致小鼠耳廓肿胀、大鼠棉球肉芽肿等急慢性炎症模型均有明显抑制作用。

Improvement for the dysmnesia of memory due to chronic blood deficiency in brain of rats induced by ligating the carotid arteries of two sides were observed. Results FBD can improve the dysmnesia of mice induced by scopolamine, NaNO2, and 45% ethanol significantly, also dysmnesia due to chronic blood deficiency in brain of rats induced by ligating the carotid arteries.

结果 FBD对由东莨菪碱所致的小鼠记忆获得障碍、亚硝酸钠所致的小鼠记忆巩固不良和45%乙醇所致的小鼠记忆再现障碍均有明显的改善作用;并可改善大鼠双侧颈总动脉结扎所致的慢性脑部供血不足而产生的记忆障碍。

Objective To explore into the probable mechanism of Alzheimer's diseaseby the acupuncture treatment combined with DGSYS of TCM.Methods Three kinds of model rats with dysmnesia which were made by injected into drug of scopolamine or NaNo 2 in the abdomen separately and injured at the hippocampal CA 1 in brian by drug of quinolinic acid treated by single acupuncture or acupuncture combined with DGSYS of TCM or DGSYS of TCM were observed separately,to compare different influence on dysfunctions of acuquisition and consoli-dation of memory induced by drugs and injure with nimodipineor the normal rats.

通过腹腔注射药物东莨菪碱或亚硝酸钠,或者用奎宁酸损毁大脑海马CA 1 区诱发大鼠发生记忆力障碍,造成不同类型的大鼠&痴呆&模型,对照性观察针刺、针刺加DGSYS、DGSYS及NM对记忆障碍功能的影响和与记忆相关实验指标参数的变化。

Li Zhongren,Shen Meihong,Mu Yanyun,et al.Nanjing University of TCM,Jiangsu210029. Objective To explore into the probable mechanism of Alzheimer's diseaseby the acupuncture treatment combined with DGSYS of TCM.Methods Three kinds of model rats with dysmnesia which were made by injected into drug of scopolamine or NaNo 2 in the abdomen separately and injured at the hippocampal CA 1 in brian by drug of quinolinic acid treated by single acupuncture or acupuncture combined with DGSYS of TCM or DGSYS of TCM were observed separately,to compare different influence on dysfunctions of acuquisition and consoli-dation of memory induced by drugs and injure with nimodipineor the normal rats.

目的 探索临床针刺加当归芍药散治疗阿尔采默氏症的可能机理方法通过腹腔注射药物东莨菪碱或亚硝酸钠,或者用奎宁酸损毁脑海马CA 1 区诱发大鼠发生记忆力障碍,造成不同类型的大鼠&痴呆&模型,对照性观察针刺、针刺加DGSYS、DGSYS及NM对记忆障碍功能的影响和与记忆相关实验指标参的变化。

Transplanted NSCs can survive for long time and differentiate into neurons in the chitosan porous scaffold within the cerebral cortex lesion of rats with TBI, which can improve the cognitive function of rats. Ectogenic NGF can accelerate all these changes.

大鼠TBI后移植的外源性NSCs可以在脑损伤区壳聚糖载体中长期存活并向神经元分化,可以改善大鼠的认知功能;NGF对其具有促进作用。

Methods Sixty rats with Walker 256 hepatoma were divided into 3 groups randomly at the 14th day after the tumors were implanted. Lipiodol 0 5 mL, lipiodol 0 5 mL plus 5 Fu 20 mg·kg -1 and routine saline 0 5 mL were injected in different groups via hepatic artery to embolize tumor of rats.

6 0只大鼠肝肿瘤模型在种植后第1 4天随机分成3组,分别经肝动脉注入超液态碘油0 。5 m L、超液态碘油0 。5 m L加5 - Fu 2 0 m g·kg- 1和生理盐水0 。5 m L。

This study chose the Lewis, a new strain rats to have successfully established the model of regional cerebral infarction using the thread to embolize and fasten the internal carotid artery where located distantly to the bifurcation of the pterygopalatine artery and ICA, and the results had been compaired with that of SD rats.

本研究采用线栓并环扎颈内动脉与翼颚动脉分叉处远端的ICA,并在一种新品系Lewis大鼠上成功地建立了局灶脑缺血模型,并与SD大鼠进行了对比。

To investigate the effects of moderate intensity endurance training (55%—75%VO 2max )on biochemical responses of diphragm,gastrocnemius and heart in normal and emphysematous rats, SD rats were randomly divided into two groups first.

在末次运动锻炼结束后 48~ 72小时处死大鼠,用组织化学方法染色,光密度分析测定膈肌肋部、腓肠肌和心肌纤维琥珀酸脱氢酶和乳酸脱氢酶活性,评价相应肌组织的氧化代谢能力。

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