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Results The results show that with duodenum or intragastric administration methods, cevadine has the obvious effects of reducing the blood pressure and slowing down the heart rate on normal cats, SHR rats and renal hypertension rats.

结果 十二指肠或灌胃给药,藜芦碱对正常猫、SHR大鼠和肾性高血压大鼠均有明显的降压和减慢心率作用,且其降压作用与剂量成正相关。

Methods The Wistar rats with streptozotocin-induced diabetes were treated with styela clava extraction and serum glucose and endothelin-1 (ET-1) of the rats were detected.

用链尿菌素建立大鼠糖尿病模型,给予海鞘提取物干预,检测血糖和血浆内皮素-1(endothelin-1, ET-1)含量。

Methods The Wistar rats with streptozotocininduced diabetes were treated with styela clava extraction and serum glucose and endothelin1(ET1) of the rats were detected.

用链尿菌素建立大鼠糖尿病模型,给予海鞘提取物干预,检测血糖和血浆内皮素-1(endothelin-1,ET-1)含量。

All ARM rats were affected by persistent cloaca or rectourethral fistula. Some experts found during the anorectal development in human beings, URS never fused with cloacal membrane, however, we thought in ETU treated rats the failure of fusion of URS with the cloacal membrane was the immediate reason of the ARM.

虽然有学者研究发现在人类正常肛门直肠发育的过程中,尿直肠隔始终没有与泄殖腔膜融合,但我们认为尿直肠隔未与泄殖腔膜融合是ETU诱导的大鼠肛门直肠畸形发生的直接原因。

The rats in the fasting group and early nutrition group were given intraperitoneal injection of balance liquid and gastric clysis of nourishment product respectively, 30 ml every 6 h within 48 h after burn injury. Subsequently, the rats were allowed access to food ad libitum until 7 th day and the mortalities of the three groups were calculated.

禁食组和早期营养组于烧伤后48 h内分别给予腹腔注射平衡液和胃灌注营养制剂,均为30 ml/,每6 h 一次;其后自由进食至实验后第7天。

Methods The procedure used autologous disc of the rats from the coccygeal intervertebral discs to impose direct pressure to the L5 dorsal root to induce an animal model of lumbar disc herniation. After the epidural tube was inserted, early prophylactic therapy and late remedial dexamethasone therapy were conducted to observed the PWMT of both hind paws of the rats.

取大鼠自体尾部椎间盘组织置于L5神经根下,建立椎间盘突出动物模型,然后硬膜外置管,采用早期预防性给药及晚期治疗性给药方法,观察地塞米松对大鼠后足底机械刺激疼痛阈值的影响。

The total RNA from brain tissue of substantia nigra of PD rats is extracted at the 1st, 2nd, 4th and 8th week and comparison is made between it and that from normal rats. The total RNA, after RNA formaldehyde degenerated sepharose electrophoresis and separation and Northern transfer, is adsorbed unto colloxylin membrane. Then ECL labeled Selenoprotein P and an unknown gene fragment are used as probes to hybridize with the RNA on the colloxylin membrane. And the hybridized result is obtained with enzyme-linked immunosorbent assay. Finally, analysis of OD is made using ONE-Dscan software.

分别提取1周、2周、1月、2月的帕金森大鼠(各8只)黑质区脑组织总RNA,并取相对应时间的正常大鼠的脑组织总RNA作为对照,经RNA甲醛变性琼脂糖凝胶电泳分离后,通过Northern转移,将其吸附在硝酸纤维素膜上,然后利用ECL标记的Selenoprotein P和一段未知基因为探针,与硝酸纤维素膜上的RNA分子进行杂交,再通过显影取得杂交的结果,应用ONE-Dscan软件进行光密度值分析。

Methods: Coloclysis the rats with 10% acetic acid solution to create acute colonitis model, after 24 hours, inject 2.5% Evan blue saline solution into the tail veins of the rats. Then, by detecting the photo-absorption rate of the EB in the tissues of the different zones of forepaws to indirectly examine the changes of blood contents in the different areas.

给予大鼠10%乙酸溶液灌肠复制急性肠损伤模型,24 h后从尾静脉注射2.5% Evans blue生理盐水溶液,通过测量前爪不同区域内EB的吸光度值大小,间接了解左右前爪各区域血含量的变化情况。

Objective To study the changes of behavior and expressions of glial fibrillary acidic protein in dorsal commissural nucleuse and thalamic intralaminar nuclei in formalin induced acute colitis in rats. Methods An animal model of acute colitis in visceralgia rats was used in this study.

目的 探讨因福尔马林引起的大鼠急性结肠炎刺激诱导的行为学变化及骶髓后连合核(dorsal commissural nucleuse, DCN)和丘脑板内核群(thalamic intralaminar nuclei, ILN)胶质原纤维酸性蛋白(glial fibrillary acidic protein, GFAP)的表达及其意义。

Five rats were randomly selected for the check of histopathology before the end of model confirmedly making, and then the model rats were randomly divided into model group and infrared group with 11 in each group.

随机取5只进行胃黏膜病理组织学检查,确认模型成功后,将造模动物随机分成非治疗组及红外线治疗组,每组11只。

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