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The rats in group C were raised without any special interposal as control group. On the 14th day of the experiment, all rats in 3 groups received esophageal acid perfusion with 0.1 mol/L HCl, the drops was kept at 37℃ and 10 mL/h, the total duration lasted 50 min.

实验第14天,对A、B、C组动物分别进行食管酸灌注,使用0.1 mol/L盐酸滴注,滴注液保持37℃,速度10 mL/h,共50 min。

Experimental models were built on the rats in experimental group.And then,these rats were divided into model group,AQP4 intervenor group,HO-1 intervenor group randomly.

对实验组的大鼠尾状核注射HB 50ul建立实验模型,确认后又随即机分为模型组、AQP4干预组和HO-1干预组,每组均为50只。

3Synaptic ultrastructure:3 rats of each group in 15 groups were chosen at random 1hour,1day,3days,1week and 3weeks.The rats were fixed by intracardial perfusing.

假手术组、模型组和电针组三组大鼠于1h、1d、3d、1周、3周五个时间段组取材进行HE染色观察大脑皮质缺血区病理学改变。

The EAE rats were induced by injecting subcutaneously an emulsion of GPSCH and CFA. In addition, each rat received an intracutaneous injection of pertussis. Albumin in serum and CSF samples was examined on the days of 4,6,8,10,12,14,16,18 and 20 p.i.. The integrity of BBB was assessed by caculating CSF to serum albumin quotient. At the same time the brains, spinal cords, thymus and inguinal lymph nodes were removed for paraffin sections cutting. These sections were used for HE staining and ICAM-1 semiquantitative immunohistochemical staining. The results showed as follows:1. None of EAE rats on days 4,6 and 8 p.i. showed clinical signs whichbecame apparent on day 10 p.i.(2.33±0.76; n=6). On days 12 and 14 p.i.

检测p.i。第4天、6天、8天、10天、12天、14天、16天、18天、20天血清和CSF中ALB含量,其CSF/S ALB比值作为评价BBB损害的指标;同时段取动物脑、脊髓、胸腺和腹股沟淋巴结制成石蜡切片行HE染色和ICAM-1半定量免疫组化分析,结果显示如下: 1、EAE大鼠p.i.4-8天无任何临床表现;p.i.10天症状开始明显,症状评分为2.33±0.76(n=6);p.i.12-14天为发病高峰期,症状评分为3.75±0.54(n=12),病情由最初的活动减少,体重减轻逐渐发展为肢体无力、瘫痪,共济失调,甚至濒死状态;p.i.16天大部分动物症状开始缓解,评分为2.08±0.66(n=6);p.i.20天疾病症状完全消失。

Enlargement of the intramammary lymph nodes with prominent MAST cells was observed in NMU-treated COP rats, but not in NMU-treated BUF rats.

NMU处理的COP大鼠乳腺组织的增大淋巴结中有大量MAST细胞聚集,BUF组无MAST细胞的聚集。

Methods: Diabetic rats were induced by an intraperitoneal injection of STZ in SD rats.

雄性SD大鼠30只,随机分为3组:正常对照组、糖尿病组和糖尿病吡格列酮治疗组。

First, we made a model of exhaustive exercise in rats, and used sucessfully the model in this study. We studied the effects of exhaustive exercise on adhesive behaviour of leukocytes in mesenteric venules by using an intravital microscope video system Its results indicated that the adhesiveness of circulating leukocytes to mesenteric venules enhanced after exhaustive exercise in rats.

首先,本文以游泳方法建立了大鼠模拟运动力竭模型,并成功地将此模型运用到本研究中;设计制作了肠系膜固定有机玻璃板,组成了一套活体显微观察实验系统;研究了大鼠运动力竭前后肠系膜微循环中白细胞粘附行为,结果表明:大鼠运动力竭后肠系膜微循环血流流态发生了明显的改变,大鼠运动力竭后肠系膜微循环中白细胞粘附性增强、白细胞滚动速率降低、在体白细胞变形性减小,将影响微循环正常的灌注,是导致微循环障碍发生发展的一个重要原因,进而最终表现为机体运动能力和运动质量下降。

Then , two groups of male rats copulated with female rats philtred in advance . Indexes of sexual function such as mount latency ,mount frequency and intromission latency were observed and recorded .

在对雌鼠给予药物催情的情况下,分两组进行交配,观察两组雄鼠爬高潜伏期,爬高总次数,插入潜伏期等性功能相关指标,并进行统计学分析。

The results showed: taurine has no significant effects on the numbers of erection, mounting, intromission and ejaculation, the latent periods of erection and catching in young rats, but can significantly increase the numbers of erection, mounting and ejaculation, obviously decrease the latent periods of erection and catching in old rats.

结果证明:牛磺酸对青年大鼠勃起次数、勃起潜伏期、乘骑次数、插入次数、射精次数、捕捉潜伏期没有影响,但可显著提高老年大鼠勃起次数、乘骑次数、射精次数,明显缩短勃起潜伏期和捕捉潜伏期。

Methods: the animal model was produced by means of putting special moulds on the male rats being bred in cages separately. Using CHAIHUSHUGAN POWDER as trial drug to smooth the circulation of liver-Qi, the targets such as oltaction-licking latency % intromission latency, intromission frequency, ejaculation latency,ejaculation frequency, post-ejaculation interval had been observed. Fluorospectrophotometry had been used to measure the content of 5-HT in respective specimen which had been produced by separating plasm, fluid of broken platelets from rats venous blood and homogenating the hypothalami.

通过带模具单笼饲养法造模,以柴胡疏肝散作为疏肝理气试验用药,观察大鼠的嗅舔潜伏期、插入潜伏期、插入次数、射精潜伏期、射精次数、射精后不应期;取大鼠静脉血和下丘脑,制备血浆、血小板破碎液和下丘脑匀浆,运用荧光分光光度法检测各标本5-HT的含量。

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