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Methods (1) The influence on the rats with non-bacterial prostatitis of 1.5% carrageenin. Rats were divided randomly into the normal control group, the model control group, the Qianliean low-dose group (1.5 g/kg), mid-dose group (3.0 g/kg), high-dose group (6.0 g/kg), with 10 rats in each group. All groups were treated continuously for 7 days, once a day. The model control group was given distilled water, 30mins after the last medication, injects 1.5% carrageenin 0.05ml in each rat's prostate, after 24hs, behead execute the rats and record the white blood cell number and Lecithin density.(2) the influence on the swelling ears of rats.

方法(1)对1.5%角叉菜胶致大鼠非细菌性前列腺炎的影响:将大鼠随机分为正常对照组、模型对照组、前列安颗粒小剂量组(1.5 g/kg)、前列安颗粒中剂量组(3.0 g/kg)、前列安颗粒大剂量组(6.0 g/kg)及阳性药前列舒乐颗粒组(2.4 g/kg)6组,每组10只,各给药组大鼠连续灌胃给药7日,每日1次,模型对照组给予等容量蒸馏水,末次给药后30 min,在每鼠前列腺内注入1.5%角叉菜胶0.05 mL,24 h后断头处死大鼠,取致炎前列腺组织,镜下记录白细胞数和卵磷脂小体密度。

Methods Thirty SD rats and 60 Wistar rats were randomly divided into isograft group as control (donors and recipients were both Wistar rats) and allograft group (the SD rats as donors, Wistar rats as recipients).

将SD大鼠和Wistar大鼠随机分为同种同基因组和同种异基因移植组。

Furthermore, in the CTA rats, compared with water stimulability, FLI neurons of SON and DMV induced by sucrose stimulability had had much more expressions.6 When the same sucrose stimulability was given, FLI neurons expressions of SON, DMV and LH in the CTA rats were much lowwer than that in the control rats.Conclusions:1 CTA had an inhibitory effect on small intestine peristalsis, indicate taste preference has an effect on small intestine peristalsis, and inhibitory effect induced by CTA is corresponded with US, this effect may have relations with vagus efferent never and humoral regulation.2 In the electrophysiology experiment, discharges of vagus efferent never in the CTA rats are much more than that in the control rats, indicates taste and taste preference may regulate small intestine peristalsis via vagus nerve, and dicharge can continude 1 hour, indicate humoral regulation also exists in the regulation.

结论1建立味觉厌恶对小肠运动有抑制作用,提示味觉嗜好性对小肠运动有影响,而且味觉厌恶引起抑制作用是与条件刺激成对应关系的,味觉刺激引起的小肠蠕动的抑制作用可能与迷走神经传出神经及体液调节有关。2在电生理实验中,CTA大鼠迷走神经传出放电高于对照组的大鼠,提示味觉及味觉嗜好性可能是通过迷走神经对小肠运动进行调节的,放电至能持续60min,表明味觉及味觉对小肠运动的调节中还有体液调节的参与。

30 Wistar rats were fed by fat milk of 1ml/100g. After three weeks adipositas Wistar rats with high levels of TC, TG and LDL, and low level of insulin sensitivity index were selected from 30 Wistar rats. T2DM model of these rats were established by vena caudalis injection of STZ, 30 mg/kg. Rats model with large vessel injury of obese T2MD were confirmed by observation of pathological change of aorta thoracica arcual.

雄性Wistar大鼠30只,每日用自制的脂肪乳1 mL/100 g灌胃,3周后挑选总胆固醇、甘油三酯、低密度脂蛋白增高,胰岛素敏感指数下降的肥胖大鼠,空腹6 h,尾静脉快速注射链脲佐菌素30 mg/kg,1周后血糖值高于16.7 mmol/L的大鼠作为T2DM模型,于成模后3周及6周观察胸主动脉弓的病理改变,证实T2DM大血管损伤模型复制成功。

The results are: 1 the stricture of the capillaries of stria vascularis was observed in most cochleae of rickety rats and, segmental deletions of the outer hair cells on the first turn of cochlea were found in a small number of rickety rats; 2 the perilymphatic ionized calcium concentration significantly re- duced and the threshold of CAP (Compound Action Poten- tials of the eighth nerve) significantly rose in rickety rats in comparison with those of normal control; 3 gentamicin results in an increase of the perilymphatic ionized calcium concentra- tion in rickety rats; 4 the cochleae of the rickety rats appeared to be less vulnerable to the ototoxicity of gentamicin than the normal one.

研究包括两个方面,其一是&佝偻病的感觉神经性耳聋及其对庆大霉素耳毒性作用的耐受性&,系用大白鼠建立维生素D缺乏性佝偻病动物模型,发现:(1)佝偻病大白鼠耳蜗血管纹毛细血管狭窄,少数动物耳蜗底回外毛细胞有节段性缺失;(2)佝偻病大白鼠的耳蜗鼓阶外淋巴钙离子浓度降低,CAP(听神经复合动作电位,以下简称CAP)听阈提高;(3)庆大霉素可使佝偻病大白鼠耳蜗外淋巴钙离子浓度上升;(4)佝偻病大白鼠耳蜗在功能和形态上都比正常者更能耐受庆大霉素的耳毒性损害。

Methods 24 SD rats were randomly divided into normal group,model group,aminophylline treatment group(35 mg/kg), 8 rats in each group. The bronchial asthma model in rats was built by egg protein sensibilization and longterm inhalation provocation. The rats in treatment group were lavaged each day from the first time of provocation.After 4week treatment, the rats were killed to obtain lung tissue for staining with HE.

24只SD大鼠随机分为正常组、模型组、治疗组,每组8只,除正常组外以卵蛋白致敏并吸入激发法制备大鼠哮喘模型,治疗组、模型组从第1次哮喘激发开始(造模第3周)分别给予氨茶碱、0.9%氯化钠溶液灌胃给药,1次/d,用药4周处死大鼠,取肺组织HE染色,用彩色图像分析仪测量支气管壁面积、支气管平滑肌面积,用ELISA双抗体夹心法测定肺组织MMP9和TIMP1含量。

Methods40 adult male SD rats were used in this study and divided into 4 groups at random: normal group, aging model group, TNY treatment group, and negative control group, each group had 10 rats. The subacutely aging rats were made by injecting Dgal into the rats' abdominal cavity continuosly. The learning and memory ability of rats in each group were detected with Morris water maze. The monoamine transmitter contents in hypothalamus and hippocampus were detected with HPLCECD.

方法选用成年雄性SD大鼠40只,随机分为4组,每组10只:正常组、衰老模型组、TNY用药组、阴性对照组。D半乳糖连续腹腔注射制作亚急性衰老的大鼠模型,采用Morris水迷宫检测各组大鼠的空间学习记忆能力及采用高效液相色谱电化学法检测各组大鼠下丘脑、海马NE,DA,5HT的含量。

Fourteen weeks later all the rats were sacrificed underwent serological test and immunohistochemical stain of liver. Results Serum level of γ-Glutamyltransferase, alkaline phosphatase, bile acid were significantly higher in DEN exposure rats than those in normal rats, and radiated rats were lower than unradiated rats, but has no significant difference.

结果诱导的肝癌大鼠,血清中γ-谷氨酰转肽酶、碱性磷酸酶、胆汁酸较正常大鼠组明显升高,毫米波照射肝癌大鼠γ-GT、AKP、BA与肿瘤对照组相比略下降,统计学上各组间无明显差异。

Methods:All the 40 Winstar rats were divided into four groups:group A:the rats were fed with normal diet,group B:the rats were fed with only high|cholesterol diet(no vitamin D3),group C:the rats were treated with one intramuscularly injection of vitamin D3(300 000 U/kg) and were denudated of endothelium,followed by high|cholesterol diet,group D:the rats were treated with 5% chitosan added into the diet besides treatment as group C.Ninety days later,the formation of atherosclerosis plaques and the activities of nitric oxide synthase in aortas in the four group rats were investigated.

40只Wistar大鼠均分为:A组;B组:饲以高脂饲料(不含维生素D3);C组:一次性给予大鼠维生素D3(30万U/kg体重)肌肉注射,以球囊损伤主动脉内皮和饲以含维生素D3(1.25×106U/kg)的高脂饲料;D组在C组的基础上饲料中加入5%壳聚糖。90 d后检测主动脉动脉粥样硬化斑块形成及NOS的活性。

Methods Twenty four female Zucker rats were divided into four groups: lean rats + vehicle, lean rats + clofibrate, obese rats + vehicle, obese rats + clofibrate. Daily intraperitoneal injection of clofibrate (300 mg/kg) or vehicle (olive oil, 1 mL/kg) was given to the rats for two weeks.

选择瘦型和肥胖型Zucker大鼠24只,分为:瘦大鼠+赋形剂组,瘦大鼠+氯苯丁酯组,肥胖大鼠+赋形剂组和肥胖大鼠+氯苯丁酯组,分别给予腹腔内注射抓苯丁酯(300mg/kg)或赋形剂(橄榄油,1mL/kg)2周。

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The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应,而且减少跟风的可能性。

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