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Methods: 45 Wistar male rats were randomly divided into fornix transection 0, 4, 7, 10 d groups and corresponding sham-operated groups and the normal group with 5 rats in each group.

成年健康雄性Wistar大鼠45只,随机分为穹窿切断0,4,7,10 d组及相应的假手术组和正常组,每组5只。

Set rats fornix transection models. The changes of expression and concentration of AVP in PVN of rats were detected by immunohistochemistry and analysis of images in each group.

建立大鼠穹窿切断模型,采用免疫组织化学和图像分析技术检测各组下丘脑PVN内AVP的表达变化和分布规律。

The AD model rats were made by cutting unilaterally the fibria fornix of male rats.

有的学者想通过神经移植来恢复 AD患者胆碱能系统的功能。

Aim:Effect of Naochuangning on memory and endothelin content in rats with open cerebral laceration was studied.Methods:The methods of opening skull and free falling body was used to cause open cerebral laceration in rats.

目的 :研究脑创宁对开放性脑挫裂伤大鼠记忆力和血清中的ET含量的影响;方法:采用开颅和自由落体法相结合,造成开放性脑挫裂伤大鼠模型。

Methods Free falling body injury method was used to establish brain contusion model in 60 SD rats. The rats in group A was given injection of 50% dextrose through jugular vein, and the those in group B were injected normal saline.

将60只健康雄性SD大鼠随机分成对照组和实验组,以自由落体法制造大鼠脑挫裂伤模型后,颈静脉置管输入50%葡萄糖溶液建立高血糖动物模型,对照组以相同方法输入等量生理盐水溶液。

Met hod: Hypertrophy of prostate model rat was established by injecting t estosterone to gelding male rats. After being treated with Qianlie Huichun ig 30 days, the rats were killed and prostate glands were resected for examination. The Fas expressio n was examined by immunobistochemical SABC.

采用大鼠去势后注射丙酸睾酮引起前列腺增生法造模,灌胃给药 30d后,处死大鼠取前列腺组织并称湿重,用免疫组化方法检测前列腺组织中Fas阳性细胞的表达率,用流式细胞术检测细胞凋亡率和观察细胞凋亡峰。

This paper is mainly comprised of two components:preparation of models of rats suffering from deficiency of spleen Yang;comparison of the pharmacodynamics impacts of different Lizhong Pills formulations made up by dried ginger or its different components in Lizhong Pills to the different groups of the models.1 Establish the model of deficiency of spleen YANG induced by " cypsum fibrosum and anemarrhenae " with complex factors1.1 ObjectivesWith using heat-clearing and fire-purging drug cypsum fibrosum and anemarrhenae,insteading of the common usage of rhubarb and folium sennae,accompanied with irregular diet and overstrained,the model of deficiency of spleen-YANG is to be established,which is much close to the pathopoiesis theory of " frigidity and chilly damaging yang,irregular diet injuring qi,overstrain impairing the spleen" in TCM.1.2 MethodsModel rats is fully fed every other day,given the molding drug of cypsum fibrosum -anemarrhenae(concentration 4:1) with 3 different frequency,and arranged to swim everyday in 25℃water until exhausted(performing as spitting bubble 3 times continuously or sinking unable to float by itself).

全文共分为脾阳虚模型的制备和干姜及其成分对理中丸药效学影响的比较两大部分。1"石膏-知母"复合法脾阳虚模型的制备1.1目的以清热泻火药石膏-知母代替常用的大黄、番泻叶类苦寒泻下药,并结合饥饱失常、劳倦过度的方法进行造模,以期建立更符合中医"寒凉伤阳、饥饱伤气和劳倦伤脾"致病思路的中医脾阳虚证候模型。1.2方法模型动物隔日足量喂食,每日在25℃水中游泳,直至大鼠连续三次吐泡下沉,或沉入水底,3秒内不能自行浮出水面,并以三种不同给药频率灌胃给予石膏一知母煎液,比较石膏-知母不同给药方法对制备脾阳虚模型的影响。

Methods Fifty one male GK rats and fifteen age- and sex-matched Wistar rats were studied.

方法采用51只雄性GK大鼠及15只年龄性别匹配的Wistar大鼠作为研究对象。

The rat model for NAFLD can be established sucessfully by feeding high fat diet, changes in glycolipid metabolism, oxidative stress and inflammatory reaction of NAFLD rats are similar to human beings, so NAFLD rats are ideal models to study human NAFLD.

2通过高脂饮食可以成功建立大鼠NAFLD模型,该模型存在着糖脂代谢紊乱及氧化应激和炎性反应,与人类NAFLD的病变相似,是研究人类NAFLD的理想模型。

MATERIAL: Thirty-six adult Sprague-Dawley rats were randomly divided into experimental group and control group, eighteen rats in each goup.

材料:健康成年SD大白鼠36只,随机分为壳聚糖组和对照组,每组18只。

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