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RESULTS: Forty rats were divided into four groups with 10 rats in each and all entered the result analysis.

结果:大鼠40只,每组10只均进入结果分析。

At all stages, the epithelial cell height of efferent ducts in the control ratswas higher than that in the tats in DES-treated rats. The epithelial cell height of efferent ducts in DES-treated rats was reduced 45% at age 10 days, 41% at age 18 days, 37% at age 25 days, 71% at age 35 days and 69% at age 60 days .

各个年龄阶段与对照组相比均有明显的下降,具有统计学意义。10天组平均高度下降了45%,18天组平均高度下降了41%,25天组平均高度下降了37%,35天组平均高度下降了71%,60天组平均高度下降了69%。

Endometriosis was surgically induced in 80 SD rats, The growth of the transplant and rats' estrus cycle was observed in different times after the implantation operation. The endometrum of the uninjured side and the ectopic endometrum were taken for observing by microscope and electroscope.

采用外科诱导法对80只大鼠行建模手术,在术后的第3周、第5周、第7周和第12周动态观察病灶的生长情况和大鼠的动情周期变化,取健侧子宫角中段的在位内膜、异位内膜行组织学研究。

But in SD rats, cardiac muscle fibers were fractured seriouly , contracted to wavilness obviously, then muscle fibers fracture were contracted like entasia by the hypoxia time increased , injury intensify , all the changes refered SD rats compensatory mechanism can not be transferred in this hypoxia degree. 3. Exposed to 4% oxygen concentration, the cardiac muscle ultrastructure of Gansu zokors had serious injury after hypoxia 2h.

在4%氧浓度的低氧耐受实验中,甘肃鼢鼠在低氧2,4h后,心肌纤维收缩明显呈波浪状,低氧时间延长至6,8和10h后,心肌显微波浪状收缩由强逐渐变弱,并逐渐恢复至正常状态,说明鼢鼠心肌在6h以后对严重缺氧环境开始代偿性适应;SD大鼠2h组心肌纤维断裂严重,收缩加强成明显的波浪状,随着低氧时间得增加,4h组呈严重成挛状收缩,损伤加剧,提示SD大鼠在这一氧浓度下已经无法正常调动其代偿机制。3。

METHODS: Sixty Sprague-Dawley male rats were randomly divided into four groups(n = 15), four methods were designed on rats models of sciatic nerve compression. There were simple decompression as group A, internal neurolysis after decompression as group B, lemithason(0.5 mg/kg) injected in the epineurium after decompression as group C, and lemithason(0.5 mg/kg) injected around the epineurium after decompression and internal neurolysis as group D.

在大鼠坐骨神经卡压模型基础上,将60只SD成年雄性大鼠随机等分为四组。A组:仅去除卡压;B组:去除卡压后切开神经外膜;C组:去除卡压后神经外膜下周围注射利美达松(0.5mg/kg);D组:去除卡压后切开神经外膜,然后在神经周围注射利美达松(0.5mg/kg)。

Methods Atherosclerotic model was developed by feeding the rats with high-cholesterol-fat diet for nine weeks and Equisetum extract and the rest of the extract were administrated to the rats at the same time.

选用雄性SD大鼠,复制食饵性动脉粥样硬化早期模型,用木贼提取物、提取剩余物分别预防性给药,以吉非罗齐为阳性药对照。

This indicates that exercise may promote bone formation and inhibit bone resorption in OVX rats to certain degree, and it confirms the success of building up a model of osteoporotic rats.

研究认为运动干预的效应主要在于抑制了OVX大鼠高转换型骨质疏松的骨吸收过程。

METHODS: Forty rats were randomly into endocrine and exocrine groups, and rats in the two groups were sub-grouped into control and experimental groups with 10 in each group.

随机将40只大鼠均分至内分泌和外分泌2个平行实验中,各分为对照组10只和实验组10只。

Objective: The purpose of our studies are gaining a better insight into the effect of genistein on mesangial cell"s phenotype change and ECM expression plus degradation under DN circumstances.We add genistein with different concentrations in high glucose cultured rat mesangial cells;feed DM rats with the single concentration genistein for different days;to explore the expression of SMemb,the mark of mesangial cell"s hypertrophy phenotype change;to examine the synthesis of Fn as well as the change of the balance between MMP-2 and TIMP-l;to comprehend its effect on renal pathological changes of DM rats and some related factors;trying toexplore the possible mechanisms.Through these studies,we will have some information about the experimental value of genistein in DN field.

目的:为了研究金雀异黄素对DN环境下大鼠MC肥大表型转换标志物SMemb和ECM分泌及降解的影响,我们拟在细胞水平以不同浓度的金雀异黄素作用于高糖培养下大鼠MC,在动物水平以同一浓度的金雀异黄素作用于DM大鼠不同时间,观察细胞表型转换标志物SMemb、ECM主要成分Fn、ECM降解酶系统基质金属蛋白酶—2(MMP-2)/基质金属蛋白酶抑制剂—1(TIMP-1)表达的变化,同时观察金雀异黄素对DM大鼠肾脏病理及影响肾脏病进展的糖脂代谢紊乱的影响,并进一步探讨金雀异黄素发挥作用的可能机制;为明确金雀异黄素在DN治疗中的地位及意义提供实验依据。

Methods 50 nude rats were submitted to intraperitoneal injection of HO-8910 cells.After 14 days,these rats was distributed according to different procedures:(1)Control group.(2)Midline laparotomy(ML,consisting in bowel exteriorization on a mesh for 1 hour following xyphopubic laparotomy).(3)Gasless laparoscopy(GL,consisting in abodominal wall expansion by a NO.14 Forley catheter for 1 hour).(4)CO2 laparoscopy(CO2 L,pneumoperitoneum with CO2 at a pressure of 2 mm Hg for 1 hour).(5)He laparoscopy(HeL,the same as CO2L except for inhalation with He).

50只裸鼠腹腔内注射卵巢癌HO-8910细胞,于14天后按不同手术要求分组如下:(1)对照组;(2)开腹组(ML,耻骨联合上正中切口长约2 cm进腹,将肠管等脏器取出搁置在无菌盐纱上,手术持续1 h);(3)气囊组(GL,腹腔内置14号Forley导尿管1根,充气后持续膨腹1 h);(4)CO2气腹组(CO2L,剑突下气腹针穿刺进腹充入CO2,压力维持在2 mm Hg,持续注入1 h);(5)He气腹组(HeL,手术步骤均同CO2气腹,仅注入气体为He)。

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