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Methods: The levels of serum sex hormones in diabetic rats, normal rats and streptozotocin rats were detected by radioimmunoassay and their sexual glands were collected and weighed and the histomorphology of testes, prostate glands and epididymides was observed under a microscope.

用放射免疫法检测糖尿病大鼠,正常大鼠和STZ大鼠血清性激素含量,同时称取性腺重量,镜检睾丸、前列腺及附睾的组织形态学改变。

Methods The contrast group was the normal adult rats and the ovariectomized rats injected by plant oil,the experiment group was the rats extirpated ovaries who were injected VE in its′ abdomen antrum:5 mg/kg,15 mg/kg,60 mg/kg VE was injected to the experiment group for continuous 9 weeks.

正常成年大鼠和注射植物油的去卵巢大鼠为对照组;腹腔注射VE的去卵巢大鼠为实验组,分别为:5 mg/kg、15 mg/kg(中剂量组、60 mg/kg,连续注射9周。

Materials and Methods: 40 Sprague-Dawley Rats were divided into five groups at random. 8 rats served as normal control group. The remaining rats were given 5/6 subtotal nephrectomies to establish the model of CRF.

目的:观测慢性肾功能衰竭(Chronic Renal Failure, CRF)肾功能、肾脏病理和血浆丙二醛、超氧化物歧化酶,以及肾、心、小肠线粒体的改变,初步探讨CRF&肾小管高代谢学说&和&尿毒症毒素致病学说&的深层机理。

Study of peripheral nerve lesions and the effects of the recipe of supplementing Qi and activating blood circulation on it in streptozotocin-induced diabetic rats: It was showed that the weight, MNCV and SNCV were significantly reduced, H reflex were significantly prolongated, the level of blood sugar were significantly increased in diabetic rats compared to normal rats at 1 week, 3 week and 5 week after STZ injection (p.05), some changes of the sciatic nerve structure were occurred after 5 weeks of the diabetic progress.

STZ大鼠周围神经功能变化及益气活血方对其影响的实验研究:STZ诱发的糖尿病大鼠,成模1W后体重减轻、血糖升高、SNCV、MNCV减慢、SNCVamp减小、SNCVlat及H反射延迟,以上各项指标与对照组相比差异显著(P均。05):成模5W后上述改变更为明显。成模5W后大鼠坐骨神经纤维出现髓鞘变性、融合、部分神经纤维变性等形态改变。

The number of BrdU labeling in the nucleus was remarked increasing onbFGF-treated pancreatitis rats than pancreatitis rats without bFGF treatment. And there was a significant difference.(P.01)ConclusionThe result of the study has demonstrated the effective therapeutic effects on acute edematous pancreatitis rats, which induces proliferation of immature acinar cells, facilitates the repair of damaged pancreatic tissues and reconstitutes tissue integrity.

兔疫组化结果显示bFGF治疗组大鼠具有BrdU标记的细胞核胰腺细胞数明显多于非治疗对照组大鼠,两者在统计学上具有显著性差异Oeq.of人结论实验结果表明bFGF对急性水肿性胰腺炎大鼠具有明显的治疗作用,它的治疗作用具体表现在诱导非成熟的胰腺细胞分化增殖,促进受损胰腺组织修复,重建组织完整性。

Every group rats were divided into two parts with the same rats. At last the rats were redivided ,then them were killed and their brains were excluded after one hour.4 hours or one week.Results PO2 and cerebral blood flow of E-selectin 2mg/kg group were higher than that of saline and lower than that of l0mg/kggroup(p.01).The volume of cerebral infarct and blood speed of E-selectin 2mg/kg group was smaller than that of saline and larger than that of l0mg/kg group(p.01).At the same time PCh.speeds.flows and the volume of infarct were related with the time (p.01).Conclusion E-selectin can effectively increase PC2 and rCBF after ischemia and reperfusion .reducing infarct volumes and speeds of blood at the same time . Artificial synthetic E-selectin can effectively reduce the reperfusion injury following cerebral ischemia.

结果 生理盐水组,2mg/kg组,10mg/kg组PO_2值依次提高(p<0.01),脑皮质血流量依次提高(p<0.01);脑血流速度依次减低;脑梗死体积依次减少(p<0.01);同时在测定的时间段里PO_2和脑组织血流量值与时间成正相关(p<0.01);脑梗死体积和脑组织血流速度值与时间成正相关(p<0.01)。E一选择素在脑缺血再灌注损伤中表达的实验研究中文摘要结论E一选择素能增加脑缺血再灌注损伤的脑组织氧饱和度,脑血流量,减低脑血流速度;减少脑损伤体积;从而保护了脑缺血再灌注损伤的脑组织。

Objective To investigate the expression of NCAM in the optic nerve regeneration model of the adult rats.Methods 64 SD rats were randomly divided into two groups.The right optic nerve of all rats were transected.

目的 检测神经细胞黏附分子在成年大鼠不同视神经再生模型中的表达,探讨NCAM分布情况与其在视神经再生中的作用。

MethodsThe 61 male Wistar rats were randomly divided into 2 groups: 11 rats were in the normal control group, the rest 50 rats were in another group, which were all induced into diabetes mellitus by injecting STZ into abdomens once.

在61只健康雄性的Wistar大白鼠中随机选取11只作为正常对照组,其余50只按50mg/kg体重一次性腹腔注射STZ,72小时后测空腹血糖,以血糖≥16.7mmol/L的大鼠作为糖尿病成功的动物模型。

The rats in the normal control group were fed with basic feed. The rats in the high-lipid model group were fed with highlipid feed. Rats in the TF group and clofibrate group were fed synchronously with high-lipid feed and total flavonoids or clofibrate for consecutive 30 days.

正常对照组饲喂基础饲料,高脂模型组饲喂高脂饲料,总黄酮大、中、小剂量组和氯苯丁酯组,在喂高脂饲料的同时给予相应剂量的药物。

Results Clofibrate normalized plasma free fatty acid and cholesterol and reduced plasma triglyceride and insulin in obese rats. However, clofibrate led to accumulation of heart TG and increased myocardial long-chain unsaturated and monounsaturated fatty acids in obese rats. Conclusion Clofibrate aggravates myocardial triglyceride accumulation in female obese Zucker rats.

结果 氯苯丁酯可使肥胖大鼠血浆游离脂肪酸和胆固醇浓度恢复正常并可降低血浆甘油三酯和胰岛素浓度,可增加肥胖大鼠心肌甘油三酯的积聚,且心肌长链不饱和脂肪酸和单不饱和脂肪酸含量也相应增加。

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