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To observe pharmacological effects of Zangqingguo Houpian on antibacterial effect in vitro,2,4-dinitrophenol induced fever in rats,the croton oil induced swelling in mouse's ear and carrageen induced WBC movement in rat chest,rat granuloma induced by tampon,acetic-acid-induced twisting test in mouse and prednisolone acetate caused immunosuppressive mice.

采用体外抗菌、对2,4-二硝基苯酚所致大鼠发热、巴豆油所致小鼠耳肿胀及角叉菜胶致大鼠胸腔白细胞游走、棉球致大鼠肉芽组织增生、冰醋酸致小鼠疼痛、醋酸泼尼松龙致免疫低下等模型,观察藏青果喉片的药效学作用。

Effects of natural cow-bezoar,cultured cow-bezoar with different bilirubin content and chicken bile on rat paw edema induced by carrageenin and formaldehyde and the postaglandin E2 (PGE2) content of inflammatory tissues of rat were determined by foot-digitoplantar turgorneter and UV spectrophotometry.

采用大鼠足跖肿胀法和紫外可见分光光度法,研究了天然牛黄、胆红素含量不同的培植牛黄以及鸡胆汁对大鼠角叉菜胶性和甲醛性的足跖肿胀率和炎性组织中PGE2含量的影响。

In this experiment,Xiaochaihu Oral Liquid was found to possess marked functions of inhibition on hydrops of rat articulatio talocruralis(p.05)induced by Carrageenin,of protection on acute liv- er function damage of rat,of depression of SGPT and LDH(p.01) and inhibition of the fever reaction of rabbit.

观察了小柴胡汤口服液的主要药理作用。研究表明,小柴胡汤口服液有显著抑制角叉菜胶诱发的大鼠踝关节水肿(p.05),保护四氯化碳所致的大鼠急性肝功能损害,有极显著降低血清SGPT及LDH的作用(P.01)。对家兔发热反应也有较好的抑制作用。

Results showed that natural cow-bezoar,cultured cow-bezoar,with medium or low bilirubin content and chicken bile(0.5 g/kg ig) could significantly inhibit rat paw edema induced by carrageenin and formaldehyde in rat.

结果表明,天然牛黄,中胆红素培植牛黄、低胆红素培植牛黄和鸡胆汁均能显著地抑制角叉菜胶和甲醛致炎后的大鼠足跖肿胀和炎性组织中的PGE2含量。

Methods Animal inflammatory models were established by injection of dimethylbenzene for mice ear swelling, carrageenin for rat footpad, cotton pellet wool for rat granuloma respectively. The content of prostaglandin E2(PGE2) and leukotriene B4(LTB4) from peritoneal macrophages were measured by RIA and RP-HPLC respectively.

采用二甲苯诱导的小鼠耳肿胀、角叉菜胶诱导的大鼠足肿胀、棉球诱导的大鼠肉芽肿模型观察TFC的抗炎作用;分别采用放射免疫法和反相高效液相色谱法检测TFC对大鼠腹腔巨噬细胞产生前列腺素E2(PGE2)和白三烯B4(LTB4)的影响。

Methods Antipyretic action of CSC was observed on rabbit fever models induced by lipopolysaccharide and rat fever models induced by baker's yeast. Rat models with pedal swelling induced by carrageenin, mouse models with auricle swelling induced by dimethylbenzene and mouse models with celiac capillary hyperpermeability induced by acetic acid were used to observe the anti- inflammatory action of CSC. Its acute toxicity in mice was also evaluated.

方法]采用细菌脂多糖致家兔发热、啤酒酵母致大鼠发热动物模型,观察穿心莲软胶囊的解热作用;采用角叉菜胶致大鼠足肿胀、二甲苯致小鼠耳肿胀和醋酸致小鼠腹腔毛细血管通透性增加的动物模型,观察穿心莲软胶囊的抗炎作用,并对小鼠进行该制剂的急性毒性试验。

Purpose To observe the effects of umbilical cataplasm on rat gastrointestinal motility and gastrointestinal hormones using rat model of gastric operation, and to explore its possible mechanism.

目的 观察敷脐巴布剂对胃手术模型大鼠胃肠运动和胃肠激素的影响,探讨其可能的作用机制。

It is clear from the comparison of the number of AmphiL34 and AmphiS29 genes with that of rat L34 and S29 genes that duplication of L34 and S29 genes occurred in vertebrates like rat. It therefore appears that the housekeeping ribosomal proteins genes such as L34 and S29 also underwent large-scale duplication during the early chordate evolution.

这一结果分别与大鼠7-9个L34拷贝数和14-17个S29拷贝数相比较,证明持家核糖体蛋白基因L34和S29基因在脊椎动物起源与进化过程中发生了大规模扩增,符合两轮基因倍增规律。

DNA fingerprinting of Wistar rat were studied with JL-02 Mulilocus probe and Southern hybridization,and comparing with different individuals of nine groups Wistar rat from six national classical area and different groups.

采用JL-02多位点探针和Southern杂交对Wistar大鼠基因组进行了DNA指纹分析,并对国内最具有典型的6个地区9个Wistar大鼠群体内和群体间进行了DNA指纹分析比较。

The aims of this study were:(1) to find methods to analyze 7-tocopherol and its metabolites;(2) to study the kinetics of 7-tocopherol metabolized in the S9 of male SD-rat liver in vitro;(3) to compare the differences of 7-tocopherol metabolized in the liver S9 of male SD-rat, male Brazil turtle and male cobia, respectively.

研究内容主要是:(1)γ-生育酚代谢物的分析方法;(2)γ-生育酚在雄性SD-大鼠肝S9的体外代谢动力学;(3)比较γ-生育酚在不同代谢水平动物的肝S9中代谢的差异。

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